Patents by Inventor Michacl Ernest Marino

Michacl Ernest Marino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticle contrast agents for diagnostic imaging
    Patent number: 8574549
    Abstract: Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprises a core, having a core surface essentially free of silica, and a shell attached to the core surface. The shell comprises at least one silane-functionalized zwitterionic moiety.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: November 5, 2013
    Assignee: General Electric Company
    Inventors: Matthew David Butts, Robert Edgar Colborn, Peter John Bonitatibus, Jr., Amit Mohan Kulkarni, Bruce Allan Hay, Andrew Soliz Torres, Brian Christopher Bales, Michacl Ernest Marino
  • NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING
    Publication number: 20100166666
    Abstract: Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprises a core, having a core surface essentially free of silica, and a shell attached to the core surface. The shell comprises at least one silane-functionalized zwitterionic moiety.
    Type: Application
    Filed: December 29, 2008
    Publication date: July 1, 2010
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Matthew David Butts, Robert Edgar Colborn, Peter John Bonitatibus, JR., Amit Mohan Kulkarni, Bruce Allan Hay, Andrew Soliz Torres, Brian Christopher Bales, Michacl Ernest Marino