Patents by Inventor Michael A. Ko
Michael A. Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240090890Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that includes an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that includes an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.Type: ApplicationFiled: November 27, 2023Publication date: March 21, 2024Applicant: ConMed CorporationInventors: John P. Greelis, Malcolm Heaven, Michael Ko, Mikxay Sirivong
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Publication number: 20240085363Abstract: In some embodiments, the present disclosure pertains to methods of detecting an analyte in a sample by associating the sample with an electrode that includes a metal-organic framework. After association, the redox properties of the electrode are evaluated. Thereafter, the presence or absence of the analyte in the sample is detected by correlating the redox properties of the electrode to the presence or absence of the analyte. In some embodiments, the present disclosure pertains to electrodes that include a metal-organic framework and an electrode surface. In particular embodiments of the present disclosure, the metal-organic framework is associated with the electrode surface. Additional embodiments of the present disclosure pertain to methods of making the electrodes of the present disclosure by associating a metal-organic framework with an electrode surface. In some embodiments, the methods of the present disclosure also include a step of mixing the metal-organic framework with a polymer.Type: ApplicationFiled: November 8, 2023Publication date: March 14, 2024Applicant: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Lukasz K. Mendecki, Michael Ko, Zheng Meng, Robert M. Stolz, Aileen Eagleton
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Patent number: 11852605Abstract: In some embodiments, the present disclosure pertains to methods of detecting an analyte in a sample by associating the sample with an electrode that includes a metal-organic framework. After association, the redox properties of the electrode are evaluated. Thereafter, the presence or absence of the analyte in the sample is detected by correlating the redox properties of the electrode to the presence or absence of the analyte. In some embodiments, the present disclosure pertains to electrodes that include a metal-organic framework and an electrode surface. In particular embodiments of the present disclosure, the metal-organic framework is associated with the electrode surface. Additional embodiments of the present disclosure pertain to methods of making the electrodes of the present disclosure by associating a metal-organic framework with an electrode surface. In some embodiments, the methods of the present disclosure also include a step of mixing the metal-organic framework with a polymer.Type: GrantFiled: June 21, 2019Date of Patent: December 26, 2023Assignee: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Lukasz K. Mendecki, Michael Ko, Zheng Meng, Robert M. Stolz, Aileen Eagleton
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Patent number: 11826039Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that includes an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that includes an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.Type: GrantFiled: February 17, 2021Date of Patent: November 28, 2023Assignee: Conmed CorporationInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Publication number: 20230285874Abstract: In some embodiments, the present disclosure pertains to a method for capturing alkenes that includes: associating the alkenes with metal-organic frameworks, where the metal-organic frameworks includes one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and oxidizing the metal-organic frameworks, where the oxidizing results in a capturing of the alkenes by the metal-organic frameworks. Additional embodiments of the present disclosure pertain to a system for capturing alkenes that includes: metal-organic frameworks, where the metal-organic frameworks include one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and an alkene feed source associated with the metal-organic frameworks, where the alkene feed source is configured to deliver an alkene feed to the system.Type: ApplicationFiled: January 31, 2023Publication date: September 14, 2023Applicant: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Xiaoping Zhang, Lukasz K. Mendecki, Zheng Meng, Michael Ko
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Patent number: 11596877Abstract: In some embodiments, the present disclosure pertains to a method for capturing alkenes that includes: associating the alkenes with metal-organic frameworks, where the metal-organic frameworks includes one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and oxidizing the metal-organic frameworks, where the oxidizing results in a capturing of the alkenes by the metal-organic frameworks. Additional embodiments of the present disclosure pertain to a system for capturing alkenes that includes: metal-organic frameworks, where the metal-organic frameworks include one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and an alkene feed source associated with the metal-organic frameworks, where the alkene feed source is configured to deliver an alkene feed to the system.Type: GrantFiled: August 9, 2018Date of Patent: March 7, 2023Assignee: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Xiaoping Zhang, Lukasz K. Mendecki, Zheng Meng, Michael Ko
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Publication number: 20220395268Abstract: Methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.Type: ApplicationFiled: August 23, 2022Publication date: December 15, 2022Applicant: Conmed CorporationInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Patent number: 11419597Abstract: Methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.Type: GrantFiled: October 26, 2017Date of Patent: August 23, 2022Assignee: Conmed CorporationInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Publication number: 20210361280Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. Also disclosed is a bone anchor that comprises a base and a top such that suture material may be attached to apertures in the anchor top or else compressed between surfaces on the base and top to secure the suture to the anchor. Also described is an inserter that can be used to insert the bone anchor into bone and move the spreader relative to the anchor body attach suture material. Also described is an inserter that can be used to insert the bone anchor into bone and move the anchor top relative to the anchor body or anchor base to attach to or clamp suture material there between.Type: ApplicationFiled: August 9, 2021Publication date: November 25, 2021Applicant: Conmed CorporationInventors: Malcolm Heaven, Mikxay Sirivong, Rudy Pretti, Michael Ko, John Greelis
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Publication number: 20210262970Abstract: In some embodiments, the present disclosure pertains to methods of detecting an analyte in a sample by associating the sample with an electrode that includes a metal-organic framework. After association, the redox properties of the electrode are evaluated. Thereafter, the presence or absence of the analyte in the sample is detected by correlating the redox properties of the electrode to the presence or absence of the analyte. In some embodiments, the present disclosure pertains to electrodes that include a metal-organic framework and an electrode surface. In particular embodiments of the present disclosure, the metal-organic framework is associated with the electrode surface. Additional embodiments of the present disclosure pertain to methods of making the electrodes of the present disclosure by associating a metal-organic framework with an electrode surface. In some embodiments, the methods of the present disclosure also include a step of mixing the metal-organic framework with a polymer.Type: ApplicationFiled: June 21, 2019Publication date: August 26, 2021Applicant: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Lukasz K. Mendecki, Michael Ko, Zheng Meng, Robert M. Stolz, Aileen Eagleton
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Patent number: 11083448Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. Also disclosed is a bone anchor that comprises a base and a top such that suture material may be attached to apertures in the anchor top or else compressed between surfaces on the base and top to secure the suture to the anchor. Also described is an inserter that can be used to insert the bone anchor into bone and move the spreader relative to the anchor body attach suture material. Also described is an inserter that can be used to insert the bone anchor into bone and move the anchor top relative to the anchor body or anchor base to attach to or clamp suture material there between.Type: GrantFiled: June 2, 2017Date of Patent: August 10, 2021Assignee: Conmed CorporationInventors: Malcolm Heaven, Mikxay Sirivong, Rudy Pretti, Michael Ko, John P. Greelis
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Publication number: 20210230191Abstract: In some embodiments, the present disclosure pertains to a method of forming metalorganic frameworks. In some embodiments, the method includes exposing a plurality of zerooxidation state metal atoms to an oxidizing agent. In some embodiments, the exposing facilitates oxidation of the plurality of zero-oxidation state metal atoms to a plurality of metallic ions. In some embodiments, the plurality of metallic ions react with a plurality of ligands to form the metal-organic frameworks. In some embodiments, the formed metal-organic frameworks comprise one or more metals and one or more ligands coordinated with the one or more metals.Type: ApplicationFiled: June 6, 2019Publication date: July 29, 2021Applicant: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Lukasz K. Mendecki, Michael KO
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Publication number: 20210177396Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that includes an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that includes an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.Type: ApplicationFiled: February 17, 2021Publication date: June 17, 2021Applicant: Conmed CorporationInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Publication number: 20210162320Abstract: In some embodiments, the present disclosure pertains to a method for capturing alkenes that includes: associating the alkenes with metal-organic frameworks, where the metal-organic frameworks includes one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and oxidizing the metal-organic frameworks, where the oxidizing results in a capturing of the alkenes by the metal-organic frame-works. Additional embodiments of the present disclosure pertain to a system for capturing alkenes that includes: metal-organic frameworks, where the metal-organic frameworks include one or more metals and one or more ligands coordinated with the one or more metals, and where the metal-organic frameworks are conductive; and an alkene feed source associated with the metal-organic frameworks, where the alkene feed source is configured to deliver an alkene feed to the system.Type: ApplicationFiled: August 9, 2018Publication date: June 3, 2021Applicant: Trustees of Dartmouth CollegeInventors: Katherine A. Mirica, Xiaoping Zhan, Lukasz K. Mendecki, Zheng Meng, Michael Ko
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Patent number: 10874818Abstract: An aerosol delivery system, which includes an aerosol delivery unit, the aerosol delivery unit including: a cartridge receiver, which is configured to receive a cartridge assembly; and an inductor configured to receive the cartridge assembly and heat a liquid formulation within a capillary tube to produce an aerosol by induction heating. The cartridge assembly including an active part of the cartridge assembly including a capillary tube; a susceptor, the susceptor configured to partially surround the capillary tube; and a pair of displaceable covers, which surround at least the capillary tube and the susceptor.Type: GrantFiled: December 26, 2017Date of Patent: December 29, 2020Assignee: Philip Morris USA Inc.Inventors: Eric Hassenpflug, Larry Keith Hooks, Jr., James A. Prescott, Ludwin Mora, Michael Scott Ulrich, Jane O'Loughlin, Steve Wilder, William G. Atterbury, Thomas D. Haubert, Ryan Somogye, Michael Ko, Stephen C. Schmitt, Michael Lorenz, Lawrence A. Weinstein, James Leamon
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Publication number: 20180333153Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that includes an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that includes an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.Type: ApplicationFiled: May 11, 2018Publication date: November 22, 2018Applicant: Conmed CorporationInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Publication number: 20180185604Abstract: An aerosol delivery system is disclosed, the system comprising: an aerosol delivery unit, the aerosol delivery unit comprising: a cartridge receiver, which is configured to receive a cartridge assembly; and an inductor configured to receive the cartridge assembly and heat a liquid formulation within a capillary tube to produce an aerosol by induction heating. The cartridge assembly including an active part of the cartridge assembly including a capillary tube; a susceptor, the susceptor configured to partially surround the capillary tube; and a pair of displaceable covers, which surround at least the capillary tube and the susceptor.Type: ApplicationFiled: December 26, 2017Publication date: July 5, 2018Applicant: Philip Morris USA Inc.Inventors: Eric Hassenpflug, Larry Keith Hooks, JR., James A. Prescott, Ludwin Mora, Michael Scott Ulrich, Jane O'Loughlin, Steve Wilder, William G. Atterbury, Thomas D. Haubert, Ryan Somogye, Michael Ko, Stephen C. Schmitt, Michael Lorenz, Lawrence A. Weinstein, James Leamon
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Patent number: 9968349Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow the use of bone anchors to secure tissue to bone.Type: GrantFiled: April 12, 2012Date of Patent: May 15, 2018Assignee: CONMED CORPORATIONInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Publication number: 20180125473Abstract: Methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.Type: ApplicationFiled: October 26, 2017Publication date: May 10, 2018Applicant: Conmed CorporationInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong
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Patent number: 9826970Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue capture anchor is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and spreader and inside surfaces of a bone hole to secure the tissue within the hole. A bone anchor is described that comprises an anchor body with expandable tines and a spreader that expands the tines into bone. The spreader captures tissue via a suture loop at the distal end of the bone anchor. Also described is an inserter that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that allow use of single bone anchor to secure tissue to bone or also to use more than one bone anchor to provide multiple lengths of suture material to compress a large area of soft tissue against bone.Type: GrantFiled: October 12, 2010Date of Patent: November 28, 2017Assignee: CONMED CORPORATIONInventors: Malcolm Heaven, Michael Ko, John P. Greelis, Mikxay Sirivong