Patents by Inventor Michael A. LaJoie

Michael A. LaJoie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR ENHANCING THE KILLING OF TARGET CELLS BY NK CELLS
    Publication number: 20200109195
    Abstract: The present disclosure provides immunotherapeutic compositions and methods for enhancing an immune response and for treating cancer or inflammatory conditions mediated by autoreactive B cells in a subject. In some aspects, multispecific antigen-binding constructs are provided that recognize at least one tumor antigen or B-lineage cell antigen and NKp30 and/or another activating NK receptor. In some aspects, multispecific antigen-binding constructs are provided that recognize at least two tumor antigens or two antigens expressed by B-lineage cells, NKp30, and another activating NK receptor. The multispecific antigen-binding constructs and methods disclosed herein can be used for the treatment of cancer, even a cancer characterized by a CD16 deficient microenvironment and/or characterized by target cells (e.g., cancer cells) having a low level of expression of the tumor antigen.
    Type: Application
    Filed: May 21, 2019
    Publication date: April 9, 2020
    Applicant: COMPASS THERAPEUTICS LLC
    Inventors: Jennifer Watkins, Michael March Schmidt, Monia Draghi, Amanda Frank Oliphant, Sara Marie Halmos, Thomas Joseph Schuetz, Jason Michael Lajoie, Allison Nelson
  • COMPOSITIONS AND METHODS FOR ENHANCING THE KILLING OF TARGET CELLS BY NK CELLS
    Publication number: 20200079867
    Abstract: The present disclosure provides immunotherapeutic compositions and methods for enhancing an immune response and for treating cancer or inflammatory conditions mediated by autoreactive B cells in a subject. In some aspects, multispecific antigen-binding constructs are provided that recognize at least one tumor antigen or B-lineage cell antigen and NKp30 and/or another activating NK receptor. In some aspects, multispecific antigen-binding constructs are provided that recognize at least two tumor antigens or two antigens expressed by B-lineage cells, NKp30, and another activating NK receptor. The multispecific antigen-binding constructs and methods disclosed herein can be used for the treatment of cancer, even a cancer characterized by a CD16 deficient microenvironment and/or characterized by target cells (e.g., cancer cells) having a low level of expression of the tumor antigen.
    Type: Application
    Filed: September 26, 2019
    Publication date: March 12, 2020
    Applicant: COMPASS THERAPEUTICS LLC
    Inventors: Jennifer Watkins, Michael March Schmidt, Monia Draghi, Amanda Frank Oliphant, Sara Marie Halmos, Thomas Joseph Schuetz, Jason Michael Lajoie, Allison Nelson
  • Display screen with icon
    Patent number: D776157
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: January 10, 2017
    Assignee: Microsoft Corporation
    Inventor: Michael A. LaJoie
  • Display screen with graphical user interface
    Patent number: D778287
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: February 7, 2017
    Assignee: Microsoft Corporation
    Inventors: Andrew M. Pickard, Raymond Alexander Malkiewicz, Michael A. LaJoie
  • Display screen with graphical user interface
    Patent number: D778288
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: February 7, 2017
    Assignee: Microsoft Corporation
    Inventors: Andrew M. Pickard, Raymond Alexander Malkiewicz, Michael A. LaJoie
  • Display screen with icon
    Patent number: D778924
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: February 14, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Michael A. LaJoie
  • Display screen with icon
    Patent number: D779506
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: February 21, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Michael A. LaJoie
  • Display screen with icon
    Patent number: D779507
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: February 21, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Matt Peltier, Michael A. LaJoie
  • Display screen with icon
    Patent number: D779508
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: February 21, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Michael A. LaJoie
  • Display screen with animated graphical user interface
    Patent number: D780193
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: February 28, 2017
    Assignee: Microsoft Corporation
    Inventors: Andrew M. Pickard, Martin Hall, Raymond Alexander Malkiewicz, Michael A. LaJoie, Conroy Williamson, Sergey Kisselev
  • Display screen with icon group and display screen with icon set
    Patent number: D780224
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: February 28, 2017
    Assignee: Microsoft Corporation
    Inventors: Martin Hall, Raymond Alexander Malkiewicz, Michael A. LaJoie
  • Display screen with graphical user interface
    Patent number: D782499
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: March 28, 2017
    Assignee: Microsoft Corporation
    Inventors: Kelly McArthur, Andrew M. Pickard, Raymond Alexander Malkiewicz, Michael A. LaJoie, Evan Amarante Soares, Kristie E. Smith
  • Display screen with icon group and display screen with icon set
    Patent number: D782500
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: March 28, 2017
    Assignee: Microsoft Corporation
    Inventors: Kelly McArthur, Raymond Alexander Malkiewicz, Michael A. LaJoie, Evan Amarante Soares, Kristie E. Smith
  • Display screen with icon
    Patent number: D782501
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: March 28, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Raymond Alexander Malkiewicz, Michael A. LaJoie
  • Display screen with icon
    Patent number: D783677
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: April 11, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Raymond Alexander Malkiewicz, Michael A. LaJoie
  • Display screen with icon
    Patent number: D783678
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: April 11, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Michael A. LaJoie
  • Display screen with icon
    Patent number: D783679
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: April 11, 2017
    Assignee: Microsoft Corporation
    Inventors: Ryan James Vulk, David Hose, Michael A. LaJoie
  • Display screen with graphical user interface
    Patent number: D785005
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: April 25, 2017
    Assignee: Microsoft Corporation
    Inventors: Kelly McArthur, Andrew M. Pickard, Raymond Alexander Malkiewicz, Michael A. LaJoie, Evan Amarante Soares, Kristie E. Smith
  • Display screen with graphical user interface
    Patent number: D787525
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: May 23, 2017
    Assignee: Microsoft Corporation
    Inventors: Kelly McArthur, Andrew M. Pickard, Martin Hall, Michael A. LaJoie, Evan Amarante Soares, Kristie E. Smith
  • Display screen with graphical user interface
    Patent number: D789944
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: June 20, 2017
    Assignee: Microsoft Corporation
    Inventors: Andrew M. Pickard, Raymond Alexander Malkiewicz, Michael A. LaJoie