Abstract: Methods, systems, and devices for providing computer-implemented services are disclosed. To provide the computer-implemented services, hardware components that generate heat may be used. To manage the heat generated by the hardware components, a heat sink assembly may be used. The heat sink assembly may include features for adjusting its shape and/or size to accommodate other nearby components. By accommodating other components, the heat sink assembly may be used in spaces that would otherwise be unusable for thermal dissipation purposes due to the risk of mechanical interference between the heat sink assembly and the other components.

Abstract: Surgical apparatus for performing in pars plana vitrectomy microsurgery including a cannula having an intraocular portion that connects to an infusion tube. The intraocular portion includes fenestrations at its distal end. The intraocular portion receives fluid through the infusion tube and dispenses the fluid through the fenestrations lessening the flow at an infusion site in an eye. The surgical apparatus includes a vitreous cutter having a suction tube at one end and a shaft at another end. The cutting port cuts vitreous into smaller pieces or a laser that liquefies the vitreous. The shaft receives the cut vitreous pieces and the suction tube draws out the cut vitreous pieces from the eye. The surgical apparatus includes a vitreoretinal surgical tool having a vitreoretinal cutter having a scissor-like or forceps-like mechanism. The vitreoretinal cutter holds and/or cuts a membrane in the eye during the microsurgery.

Abstract: A hole saw is disclosed herein. The hole saw can include a cylindrical body having inner and outer cylindrical surfaces concentric to each other about a first axis. The body can also extend along the first axis between first and second opposite ends. The hole saw can also include a plurality of teeth each including a tooth body and a carbide tip positioned on the tooth body and forming a tooth face. Each of the tooth faces can define one or more cutting edges. The teeth can be arranged in an alternating pattern including a first tooth in the form of a chisel tooth, a second tooth immediately behind the first tooth and in the form of an offset grind tooth, and a third tooth immediately behind the second tooth and in the form of a triple chip grind tooth.

Abstract: A latch and lock assembly includes a lever pivotable between a latched and unlatched position. A first actuator selectively moves a locking tab between a locked and unlocked position. In the locked position, the locking tab blocks pivotable movement of the lever from the latched position to the unlatched position. In the unlocked position, the locking tab allows pivotable movement of the lever from the latched position to the unlatched position. A second actuator selectively rotates a door opening tab between a first and second position when the locking tab is in the unlocked position is included. When the door opening tab is in the first position the lever is in a latched position, and when the door opening tab is rotated from the first position to the second position, the door opening tab abuts the lever and urges the lever from the latched position to the unlatched position.

Abstract: The present invention relates to antibodies that specifically bind to one or more of IL-4, IL-13, IL-33, TSLP, and p40. The present invention further relates to antibodies that bind to one of IL-4, IL-13, IL-33, or TSLP. The invention further relates to multispecific antibodies that specifically bind to IL-4 and IL-13, and at least one other target. The present invention relates to multispecific antibodies that bind IL-4, IL-13, and one of IL-33, TSLP, or p40. The present invention also pertains to related molecules, e.g. nucleic acids which encode such antibodies or multispecific antibodies, compositions, and related methods, e.g., methods for producing and purifying such antibodies and multispecific antibodies, and their use in diagnostics and therapeutics.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: Example fluid collection systems and methods of collecting fluid are described. The fluid collection system includes a fluid collection device and one or more straps secured or securable to the fluid collection device. The one or more straps are configured to wrap around the user to secure the fluid collection device adjacent to the urethra of the user.

Abstract: A hole saw is disclosed herein. The hole saw can include a cylindrical body having inner and outer cylindrical surfaces concentric to each other about a first axis. The body can also extend along the first axis between first and second opposite ends. The hole saw can also include a plurality of teeth each including a tooth body and a carbide tip positioned on the tooth body and forming a tooth face. Each of the tooth faces can define one or more cutting edges. The teeth can be arranged in an alternating pattern including a first tooth in the form of a chisel tooth, a second tooth immediately behind the first tooth and in the form of an offset grind tooth, and a third tooth immediately behind the second tooth and in the form of a triple chip grind tooth.

Abstract: Example fluid collection systems and methods of use are described. The fluid collection system includes a garment and a fluid collection device. The garment is configured to be worn on a pelvis of a user, and includes at least a crotch portion having an inner surface and at least one of a strap partially defining a through hole between the strap and the inner surface or a pocket on the inner surface of the crotch portion. The at least one of the strap or the pocket are positioned on the crotch portion of the garment and the fluid collection device is sized to position the opening and the fluid permeable body proximate to a urethra of the user.

Abstract: Surgical apparatus for performing a microsurgery including a cannula having an intraocular portion. The intraocular portion connects to an infusion tube. The intraocular portion includes fenestrations at its distal end. The intraocular portion receives fluid through the infusion tube and dispenses the fluid through the fenestrations lessening the flow at an infusion site in an eye. The surgical apparatus includes a vitreous cutter. The vitreous cutter includes a suction tube at one end and a shaft at another end. The cutting port cuts vitreous into smaller pieces or a laser that liquefies the vitreous. The shaft receives the cut vitreous pieces and the suction tube draws out the cut vitreous pieces from the eye. The surgical apparatus includes a vitreoretinal surgical tool having a vitreoretinal cutter. The vitreoretinal cutter has a scissor-like or forceps-like mechanism. The vitreoretinal cutter holds and/or cuts a membrane in the eye during the microsurgery.

Abstract: Systems and methods consistent with the invention may include receiving, by a portal, requests from entities to become members, selectively granting the requests by the portal, receiving information by the portal from a plurality of first members, in response to requests from the first members, creating member files in the database using the received information, the files corresponding to the first members, receiving an information request by the portal from a second member, and selectively supplying by the portal to the second member, information from at least one of the files, the supplied information being selected based on the requests.

Abstract: Described is a particle having a platinum-group catalyst that is fully encapsulated within a thermoplastic polymer. The particle can be used in a curable organopolysiloxane composition that also includes organopolysiloxane components.

Abstract: Surgical apparatus for performing in pars plana vitrectomy microsurgery including a cannula having an intraocular portion that connects to an infusion tube. The intraocular portion includes fenestrations at its distal end. The intraocular portion receives fluid through the infusion tube and dispenses the fluid through the fenestrations lessening the flow at an infusion site in an eye. The surgical apparatus includes a vitreous cutter having a suction tube at one end and a shaft at another end. The cutting port cuts vitreous into smaller pieces or a laser that liquefies the vitreous. The shaft receives the cut vitreous pieces and the suction tube draws out the cut vitreous pieces from the eye. The surgical apparatus includes a vitreoretinal surgical tool having a vitreoretinal cutter having a scissor-like or forceps-like mechanism. The vitreoretinal cutter holds and/or cuts a membrane in the eye during the microsurgery.

Abstract: Systems and methods for producing more accurate, intricate structures via digital light processing additive manufacturing are provided. One or more digital transformations, or filters, are applied to 2D-images used to print the part to help eliminate the effects of scatter. The digital transformations can lead to higher doses of light to be applied to edges and smaller features while limiting an amount of exposure to light of larger features to avoid over-curing of the larger features. This can help keep the integrity of certain designs, such as lattices and other structures that are intended to have some porosity. The digital transformations can also be used in a diagnostic manner to help provide feedback on performance.

Abstract: Methods and systems for designing and manufacturing RF devices is provided. The disclosed methods allow for quick and efficient printing without having to generate a CAD file or the like to generate the build file. This can be achieved by receiving RF inputs, such as inputs generated from an RF simulation, and combining that with geometry design data, such as boundary geometry information that can include an outer geometry and size of the device to be printed. Further, the RF devices that are produced can use triply periodic minimal surface constructs as the base element of the device.

Abstract: A surgical apparatus for performing a microsurgery including a cannula having an intraocular portion. The intraocular portion connects to an infusion tube. The intraocular portion includes fenestrations at its distal end. The intraocular portion receives fluid through the infusion tube and dispenses the fluid through the fenestrations lessening the flow at an infusion site in an eye. The surgical apparatus includes a vitreous cutter. The vitreous cutter includes a suction tube at one end and a shaft at another end. The cutting port cuts vitreous into smaller pieces or a laser that liquefies the vitreous. The shaft receives the cut vitreous pieces and the suction tube draws out the cut vitreous pieces from the eye. The surgical apparatus includes a vitreoretinal surgical tool having a vitreoretinal cutter. The vitreoretinal cutter has a scissor-like or forceps-like mechanism. The vitreoretinal cutter holds and/or cuts a membrane in the eye during the microsurgery.

Abstract: An example fluid collection assembly includes a fluid impermeable barrier defining at least one opening, a chamber in fluid communication with the at least one opening, and at least one fluid outlet. The fluid collection assembly also includes at least one porous material (e.g., at least one wicking material) disposed in the chamber. The fluid collection assembly also includes at least one conduit attached to the fluid outlet. Further, the fluid collection assembly includes one or more leak prevention features.