Patents by Inventor Michael A. Whitney

Michael A. Whitney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9808532
    Abstract: Disclosed herein, in certain embodiments, is a selective transport molecule with increased in vivo circulation. In some embodiments, a selective transport molecule disclosed herein has the formula (A-X-B-C)n-M, wherein C is a cargo moiety; A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutatmates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and M is a macromolecular carrier.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: November 7, 2017
    Assignee: The Regents of the University of California
    Inventors: Roger Tsien, Emilia Olson, Tao Jiang, Quyen Nguyen, Michael Whitney
  • Patent number: 9783417
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: October 10, 2017
    Assignee: ThermoChem Recovery International, Inc.
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20170166446
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Application
    Filed: February 13, 2017
    Publication date: June 15, 2017
    Applicant: ThermoChem Recovery International, Inc.
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20170152140
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Application
    Filed: February 13, 2017
    Publication date: June 1, 2017
    Inventors: RAVI CHANDRAN, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20170152139
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Application
    Filed: February 13, 2017
    Publication date: June 1, 2017
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20170058221
    Abstract: A solids circulation system receives a gas stream containing char or other reacting solids from a first reactor. The solids circulation system includes a cyclone configured to receive the gas stream from the first reactor, a dipleg from the cyclone to a second reactor, and a riser from the second reactor which merges with the gas stream received by the cyclone. The second reactor has a dense fluid bed and converts the received materials to gaseous products. A conveying fluid transports a portion of the bed media from the second reactor through the riser to mix with the gas stream prior to cyclone entry. The bed media helps manipulate the solids that is received by the cyclone to facilitate flow of solids down the dipleg into the second reactor. The second reactor provides additional residence time, mixing and gas-solid contact for efficient conversion of char or reacting solids.
    Type: Application
    Filed: November 9, 2016
    Publication date: March 2, 2017
    Inventors: Ravi CHANDRAN, Jonathan A. ZENE, Dave G. NEWPORT, Hamilton Sean Michael WHITNEY
  • Patent number: 9580315
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: February 28, 2017
    Assignee: ThermoChem Recovery International, Inc.
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20170051217
    Abstract: A solids circulation system receives a gas stream containing char or other reacting solids from a first reactor. The solids circulation system includes a cyclone configured to receive the gas stream from the first reactor, a dipleg from the cyclone to a second reactor, and a riser from the second reactor which merges with the gas stream received by the cyclone. The second reactor has a dense fluid bed and converts the received materials to gaseous products. A conveying fluid transports a portion of the bed media from the second reactor through the riser to mix with the gas stream prior to cyclone entry. The bed media helps manipulate the solids that is received by the cyclone to facilitate flow of solids down the dipleg into the second reactor. The second reactor provides additional residence time, mixing and gas-solid contact for efficient conversion of char or reacting solids.
    Type: Application
    Filed: November 9, 2016
    Publication date: February 23, 2017
    Applicant: Thermochem Recovery International, Inc.
    Inventors: Ravi CHANDRAN, Jonathan A. ZENZ, Dave G. NEWPORT, Hamilton Sean Michael WHITNEY
  • Publication number: 20170029466
    Abstract: A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. X may be cleaved extracellularly or intracellularly. The molecules of the present invention may be linear, cyclic, branched, or have a mixed structure.
    Type: Application
    Filed: June 29, 2015
    Publication date: February 2, 2017
    Inventors: Tao Jiang, Emilia S. Olson, Michael Whitney, Roger Tsien
  • Patent number: 9550950
    Abstract: A solids circulation system receives a gas stream containing char or other reacting solids from a first reactor. The solids circulation system includes a cyclone configured to receive the gas stream from the first reactor, a dipleg from the cyclone to a second reactor, and a riser from the second reactor which merges with the gas stream received by the cyclone. The second reactor has a dense fluid bed and converts the received materials to gaseous products. A conveying fluid transports a portion of the bed media from the second reactor through the riser to mix with the gas stream prior to cyclone entry. The bed media helps manipulate the solids that is received by the cyclone to facilitate flow of solids down the dipleg into the second reactor. The second reactor provides additional residence time, mixing and gas-solid contact for efficient conversion of char or reacting solids.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: January 24, 2017
    Assignee: Thermochem Recovery International, Inc.
    Inventors: Ravi Chandran, Jonathan A. Zenz, Dave G. Newport, Hamilton Sean Michael Whitney
  • Patent number: 9499404
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: November 22, 2016
    Assignee: ThermoChem Recovery International, Inc.
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20160207273
    Abstract: A feeder system for advancing a compressible material has a hydraulic circuit associated with a final compression stage. The hydraulic circuit includes a platen attached to a primary ram configured to travel within a primary cylinder. The platen is operatively connected to a main piston cylinder assembly and at least two ancillary piston cylinder assemblies. In a first mode of operation, the hydraulic circuit forces the ancillary piston cylinder assemblies to advance the platen and ram in a forward compression direction until they reach a first predetermined position between travel extremes, while the main piston cylinder assembly passively travels along in the forward compression direction. Once the first predetermined position is reached, in a second mode of operation, the hydraulic circuit additionally forces the main piston cylinder assembly to compress the compressible material. In a third mode of operation, the hydraulic circuit retracts the platen and primary ram.
    Type: Application
    Filed: March 31, 2016
    Publication date: July 21, 2016
    Inventors: MILAN JOHN MARKOVICH, David G. NEWPORT, Hamilton Sean Michael WHITNEY
  • Publication number: 20160068392
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 10, 2016
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20160059176
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 3, 2016
    Inventors: Ravi CHANDRAN, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20160060110
    Abstract: A system and method for processing unconditioned syngas first removes solids and semi-volatile organic compounds (SVOC), then removes volatile organic compounds (VOC), and then removes at least one sulfur containing compound from the syngas. Additional processing may be performed depending on such factors as the source of syngas being processed, the products, byproducts and intermediate products desired to be formed, captured or recycled and environmental considerations.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 3, 2016
    Applicant: ThermoChem Recovery International, Inc.
    Inventors: Ravi Chandran, Daniel Michael Leo, Shawn Robert Freitas, Dave G. Newport, Hamilton Sean Michael Whitney, Daniel A. Burciaga
  • Publication number: 20160030903
    Abstract: A mechanism applies necessary forces for the creation of one or more plugs of compressible material to be supplied to a reactor. The plugs are capable of forming a seal between inlets for the plugs and the reactor. The mechanism includes two double-acting hydraulic piston cylinder assemblies coupled with two single-acting hydraulic piston cylinder assemblies.
    Type: Application
    Filed: April 10, 2013
    Publication date: February 4, 2016
    Inventors: DANIEL MICHAEL LEO, Hamilton Sean Michael WHITNEY
  • Publication number: 20160031177
    Abstract: A feeder system for advancing a compressible material has a hydraulic circuit associated with a final compression stage. The hydraulic circuit includes a platen attached to a primary ram configured to travel within a primary cylinder. The platen is operatively connected to a main piston cylinder assembly and at least two ancillary piston cylinder assemblies. In a first mode of operation, the hydraulic circuit forces the ancillary piston cylinder assemblies to advance the platen and ram in a forward compression direction until they reach a first predetermined position between travel extremes, while the main piston cylinder assembly passively travels along in the forward compression direction. Once the first predetermined position is reached, in a second mode of operation, the hydraulic circuit additionally forces the main piston cylinder assembly to compress the compressible material. In a third mode of operation, the hydraulic circuit retracts the platen and primary ram.
    Type: Application
    Filed: April 8, 2013
    Publication date: February 4, 2016
    Inventors: Milan John MARKOVICH, David G. NEWPORT, Hamilton Sean Michael WHITNEY
  • Patent number: 9188146
    Abstract: A tensioning system for tensioning a stud is provided. The system includes a nut having an external surface, an internal surface engaging the external surface of the stud or puller screw, and at least two bores defined therein. The posts have first and second ends and are disposed in the bores. The first ends engage a stop surface, and the second ends extend outwardly from the bores. A cylinder includes an internal surface engaged with the external surface of the nut, and has a bore defined therein. A locking screw may be threadably positioned within the cylinder bore and engages the nut. A piston is positioned within the cylinder to define a hydraulic chamber and is configured for being engaged with the second ends of the posts. Further, a biasing member is disposed between the nut and piston. A tensioning system safety guard is also provided.
    Type: Grant
    Filed: August 1, 2011
    Date of Patent: November 17, 2015
    Assignee: Riverhawk Company
    Inventors: Timothy J. Trautman, Patrick Shawn Reilly, Richard Joseph Donegan, Robert Michael Whitney
  • Patent number: 9072792
    Abstract: A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. X may be cleaved extracellularly or intracellularly. The molecules of the present invention may be linear, cyclic, branched, or have a mixed structure.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: July 7, 2015
    Assignee: The Regents of the University of California
    Inventors: Tao Jiang, Emilia S. Olson, Michael Whitney, Roger Tsien
  • Publication number: 20150184091
    Abstract: A solids circulation system receives a gas stream containing char or other reacting solids from a first reactor. The solids circulation system includes a cyclone configured to receive the gas stream from the first reactor, a dipleg from the cyclone to a second reactor, and a riser from the second reactor which merges with the gas stream received by the cyclone. The second reactor has a dense fluid bed and converts the received materials to gaseous products. A conveying fluid transports a portion of the bed media from the second reactor through the riser to mix with the gas stream prior to cyclone entry. The bed media helps manipulate the solids that is received by the cyclone to facilitate flow of solids down the dipleg into the second reactor. The second reactor provides additional residence time, mixing and gas-solid contact for efficient conversion of char or reacting solids.
    Type: Application
    Filed: March 13, 2015
    Publication date: July 2, 2015
    Applicant: Thermochem Recovery Intemational, Inc.
    Inventors: Ravi Chandran, Jonathan A. ZENZ, Dave G. NEWPORT, Hamilton Sean Michael WHITNEY