Abstract: The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide from an S. pneumoniae serotype conjugated to a carrier protein, wherein the serotypes of S. pneumoniae are as defined herein. Also provided are methods for inducing a protective immune response in a human patient comprising administering the multivalent immunogenic compositions of the invention to the patient. The multivalent immunogenic compositions are useful for providing protection against S. pneumoniae infection and diseases caused by S. pneumoniae. The compositions of the invention are also useful as part of treatment regimes that provide complementary protection for patients that have been vaccinated with a multivalent vaccine indicated for the prevention of pneumococcal disease.

Abstract: A magnetic toy figure includes a torso extending along a torso axis. The torso includes a first torso side, a second torso side opposite the first torso side, a base torso side extending between the first and second torso sides, and a head torso side extending between the first and second torso sides and spaced from the base torso side. The magnetic toy figure also includes a first arm coupled to the first torso side, a second arm coupled to said second torso side, a leg coupled to and extending away from the base torso side, and a head coupled to and extending away from the head torso side along the torso axis. The magnetic toy figure further includes a first magnet coupled to the first arm, a second magnet coupled to the second arm, a leg magnet coupled to the leg, and a head magnet coupled to said head.

Abstract: Polymeric electro spray emitters and related methods are generally described. In some embodiments, an emitter may be made from an ionic electro active polymer. The composition of the electro spray emitters described herein may enable the transport of ions and/or liquid ion sources, such as an ionic liquid or room temperature molten salt, through the bulk of the polymeric emitter. In some embodiments, the described emitters may be fabricated using a mixture of an ionic electroactive polymer, a solvent, and a liquid ion source to at least partially mitigate swelling effects of the polymer emitter that may otherwise occur when the one or more emitters are exposed to the liquid ion source during operation.

Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user.

Abstract: A reinforcing system for a vessel that can contain water is described. The system includes a shell for containing water, the shell having one or more jets extending therethrough from an inside of the shell to an outside of the shell, and a structural support layer on an underside of the shell. The structural support layer can include: an inner layer of rigidizer applied to the underside of the shell, a central low density core, and an outer layer of rigidizer applied to the central low-density core. The structural support layer can extend from a bottom side of the underside of the shell, across at least one sidewall of the underside of the shell, and form at least one rib along the sidewall of the underside of the shell.

Abstract: Provided herein are novel antigen binding domains and antibodies (e.g., heterodimeric antibodies) that bind Prostate Specific Membrane Antigen (PSMA). In exemplary embodiments, the anti-PSMA antibodies also bind CD3. Such antibodies that bind PSMA and CD3 are useful, for example in the treatment of PSMA-related cancer.

Abstract: Described herein is a computer implemented method. The method includes displaying, on a display, a scene timeline including a time-ordered sequence of scene previews, each scene preview corresponding to a scene of a video production and having a display width that provides a visual indication of a duration of that scene. The method further includes displaying a canvas including a first visual element that is associated with the first scene, and in response to detecting selection of the first visual element from the canvas, causing a first visual element timing indicator to be displayed. The first visual element timing indicator is aligned with the scene timeline based on a first visual element start time and a first visual element end time.

Abstract: Techniques for integrating sensor data into a scene or map based on statistical data of captured environmental data are discussed herein. The data may be stored as a multi-resolution voxel space and the techniques may comprise first applying a pre-alignment or localization technique prior to fully integrating the sensor data.

Abstract: This application describes a sprayer assembly that can attach to a variety of different types of pre-filled, fluid containers (e.g., non-pressurized fluid containers) for holding the fluid to be sprayed. For example, the sprayer assembly can include a sprayer-head assembly for attaching to a container of fluid, a canister for holding the container of fluid, or any combination thereof In addition, the sprayer assembly can be connected to a variety of different types of pressurized air sources. The sprayer-head assembly can include a nozzle assembly (e.g., fluid uptake tube, valve, and nozzle head), as well as a trigger for actuating the nozzle assembly.

Abstract: A chair hanger system includes a front plate, a back plate opposing the front plate, and a plate separator defining a gap between the front plate and the back plate. A first and second hook are attached to the back plate, the first hook defining a first opening geometry and the second hook defining a second opening geometry.

Abstract: In various embodiments, an improved flexible-composite material is described that comprises at least one scrim constructed from at least two unidirectional tape layers bonded together and at least one woven fabric, non-woven fabric, or membrane bonded to the scrim. In various embodiments, the unidirectional tape layers comprise a plurality of parallel fiber bundles comprising monofilaments within an adhesive resin. In various embodiments, the fiber bundles are separated by gaps that can be filled in by adhesive or non-adhesive resin.

Abstract: A method for compressing a volumetric video stream comprising a plurality of frames, each associated with a mesh and a texture, with groups of frames being defined, each comprising a key frame and inter frames having meshes defined with respect to the mesh of the corresponding key frame, the method comprising: a step of compressing information representative of the textures, including, for each frame group, steps of block compressing the information representative of the textures of each of the frames, thus defining blocks of pixels; determining first blocks which can form a composite texture of the key frame and second blocks which can modify this composite texture through iterative substitutions so as to form approximate inter-frame textures; and encoding the inter-frame textures on the basis of the composite texture of the key frame and the second blocks.

Abstract: A system for generating an input signal for a video game includes: a receiving unit configured to receive a video game output signal output by a video game playing device during the playing of a video game; a reasoning model configured to determine an action to take within the video game based on the received video game output signal, the reasoning model being configured to generate a representation of the determined action that is independent of the video game; and an encoding unit configured to translate the representation into an input signal and to provide the input signal to a video game playing device at which the video game is being played, thereby causing the determined action to be performed within the video game.

Abstract: Methods of controlling an in-line heater for an energy storage device are provided. A determination is made that a pump is running. When running, the pump circulates a thermal management fluid through a thermal management conditioning loop, which includes the in-line heater and a heat transfer hardware configured to transfer heat between the thermal management fluid and the energy storage device, wherein the in-line heater is in thermal communication with the thermal management fluid. The in-line heater is turned on in response to the determination that the pump is running and a temperature of the thermal management fluid is below a lower control limit.

Abstract: A thermal management system for an energy storage system, the energy storage system comprising an energy storage device, an energy storage monitoring system including circuitry dedicated and configured to monitor a temperature of the energy storage device. The thermal management system comprises: a thermal management conditioning loop, a pump configured to circulate a thermal management fluid through the thermal management conditioning loop, a heat source, and a heat transfer hardware in thermal communication with the energy storage device. An energy storage controller of the energy storage monitoring system is configured to confirm that a temperature of the thermal management fluid and/or a temperature of the energy storage device is below an upper safety limit, between a lower control limit and an upper control limit, or both, and in response, to send an enable heater request indicating the heat source is to turn on.

Abstract: The present invention relates to a hemostatic elastin-like polypeptide comprising a glutamine embedded in a Q-block sequence and, optionally, a lysine embedded in a K-block sequence. Under physiological setting, the Q-block sequence and the K-block sequence are recognized by human transglutaminase factor XIIIa and crosslinked with fibrin networks. The present invention also relates to the medical use of the polypeptide, to a nucleic acid sequence encoding the polypeptide, to an expression vector comprising the nucleic acid sequence, and to a cell comprising the nucleic acid sequence or the expression vector.

Abstract: A novel maize variety designated X05V409 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X05V409 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X05V409 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X05V409, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X05V409 are provided. Methods for producing maize varieties derived from maize variety X05V409 and methods of using maize variety X05V409 are disclosed.

Abstract: A system and method for reinforcing a spa shell includes a structural support layer on an underside of the spa shell. The structural support layer may include an inner layer of rigidizer, a central foam layer, and an outer layer of rigidizer. The structural support layer may extend from a bottom side of the underside of the spa shell, across at least one sidewall of the underside of the spa shell to a lip of the spa shell, the structural support layer forming at least one rib along the sidewall of the underside of the spa shell.

Abstract: In various embodiments, an improved flexible-composite material is described that comprises at least one scrim constructed from at least two unidirectional tape layers bonded together and at least one woven fabric, non-woven fabric, or membrane bonded to the scrim. In various embodiments, the unidirectional tape layers comprise a plurality of parallel fiber bundles comprising monofilaments within an adhesive resin. In various embodiments, the fiber bundles are separated by gaps that can be filled in by adhesive or non-adhesive resin.

Abstract: A method of preparing a filter for delivery into a body vessel. The filter includes a hub disposed along a longitudinal axis and a plurality of anchor members extending from the hub. Each anchor member includes either a cranial extension or a caudal extension at a distal end thereof. At least one anchor member distal end may be spaced from the hub at each of a first, second, and third distance along the longitudinal axis. The filter also includes a plurality of locator members extending from the hub, the locator members alternatingly interposed between the anchor members.