Patents by Inventor Michael Alexander Brown
Michael Alexander Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240157273Abstract: The invention provides a method for generating a daughter isotope, the method comprising contacting an ion exchange column with parent isotope; allowing the column to equilibrate between the parent and daughter isotopes; eluting the daughter isotope from the column; and repeating the equilibration and elution steps. Also provided is a system for repeatedly generating isotopes from the same support column over time with a single loading of parent isotope, the system comprising a radiation-resistant sorbent column; a parent isotope permanently contained within the column; and a fluid to elute daughter isotope from the column.Type: ApplicationFiled: November 15, 2022Publication date: May 16, 2024Applicant: UCHICAGO ARGONNE, LLCInventor: Michael Alexander Brown
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Patent number: 11217355Abstract: The invention provides a method for generating medical isotopes, the method comprising contacting a primary radiation beam with a converter for a time sufficient to produce a secondary beam of gamma particles, and contacting the beam of gamma particles to a target, where the cross section dimension of the beam of gamma particles is similar to the cross section dimension of the target. Both the converter and target are small in diameter and very closely spaced. Also provided is a system for producing medical isotopes, the device comprising a housing having a first upstream end and a second downstream end, a radiotransparent channel (collimator) with a first upstream end and a downstream end, wherein the upstream end is adapted to receive a radiation beam, a target positioned downstream of the downstream end of the channel and coaxially aligned with the channel, wherein the target has a cross section that is similar to the cross section of the channel.Type: GrantFiled: September 28, 2018Date of Patent: January 4, 2022Assignee: UCHICAGO ARGONNE, LLCInventors: Jerry A. Nolen, Jr., Michael Alexander Brown, David A. Rotsch, Sergey D. Chemerisov, Walter F. Henning, Jeongseog Song
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Patent number: 10704123Abstract: The invention provides a method for isolating medical isotopes, the method having the steps of dissolving titanium nuclear targets to create a solution; contacting the solution with a resin so as to retain the isotopes on the resin and generate an eluent containing titanium; contacting the isotope-containing resin with acid of a first concentration to remove impurities from the resin; and contacting the isotope-containing resin with an acid of a second concentration to remove isotope from the resin.Type: GrantFiled: July 3, 2019Date of Patent: July 7, 2020Assignee: UCHICAGO ARGONNE, LLCInventors: Michael Alexander Brown, Jerry A. Nolen, Jr., David Alan Rotsch
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Publication number: 20200066418Abstract: A system for producing and harvesting radioisotopes is provided, the system having a converter housing defining a first beam window; a converter carrier and cartridge in slidable communication with the converter housing; a target housing positioned downstream from the converter housing, the target housing defining a second beam window; and a target carrier in slidable communication with the target housing.Type: ApplicationFiled: August 27, 2018Publication date: February 27, 2020Applicant: UCHICAGO ARGONNE, LLCInventors: David A. Rotsch, Nicholas A. Smith, David A. Ehst, Sergey A. Chemerisov, Jerry A. Nolen, JR., Michael Alexander Brown, James J. Grudzinski, James L. Bailey, Ronald T. Kmak
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Publication number: 20190338394Abstract: The invention provides a method for isolating medical isotopes, the method having the steps of dissolving titanium nuclear targets to create a solution; contacting the solution with a resin so as to retain the isotopes on the resin and generate an eluent containing titanium; contacting the isotope-containing resin with acid of a first concentration to remove impurities from the resin; and contacting the isotope-containing resin with an acid of a second concentration to remove isotope from the resin.Type: ApplicationFiled: July 3, 2019Publication date: November 7, 2019Applicant: UCHICAGO ARGONNE, LLCInventors: Michael Alexander Brown, Jerry A. Nolen, JR., David Alan Rotsch
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Patent number: 10344355Abstract: The invention provides a method for isolating scandium, the method having the steps of dissolving titanium nuclear targets to create a solution; contacting the solution with a resin so as to retain scandium on the resin and generate an eluent containing titanium; contacting the scandium-containing resin with acid of a first concentration to remove impurities from the resin; and contacting the scandium-containing resin with an acid of a second concentration to remove scandium from the resin.Type: GrantFiled: August 22, 2016Date of Patent: July 9, 2019Assignee: UCHICAGO ARGONNE, LLCInventors: Michael Alexander Brown, David Alan Rotsch, Jerry A. Nolen, Jr.
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Publication number: 20190103198Abstract: The invention provides a method for generating medical isotopes, the method comprising contacting a primary radiation beam with a converter for a time sufficient to produce a secondary beam of gamma particles, and contacting the beam of gamma particles to a target, where the cross section dimension of the beam of gamma particles is similar to the cross section dimension of the target. Both the converter and target are small in diameter and very closely spaced. Also provided is a system for producing medical isotopes, the device comprising a housing having a first upstream end and a second downstream end, a radiotransparent channel (collimator) with a first upstream end and a downstream end, wherein the upstream end is adapted to receive a radiation beam, a target positioned downstream of the downstream end of the channel and coaxially aligned with the channel, wherein the target has a cross section that is similar to the cross section of the channel.Type: ApplicationFiled: September 28, 2018Publication date: April 4, 2019Applicant: UCHICAGO ARGONNE, LLCInventors: Jerry A. Nolen, Jr., Michael Alexander Brown, David A. Rotsch, Sergey D. Chemerisov, Walter F. Henning, Jeongseong Song
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Patent number: 10221466Abstract: The invention provides a method for extracting transition metals, the method comprising supplying a feedstream containing transition metal, mixing the feedstream with nitric acid for a time and at a concentration sufficient to form an aqueous phase containing the transition metal, combining the aqueous phase with organic extractant phase for a time and at a concentration sufficient to cause the transition metal to reside within the organic extractant phase, and combining the transition metal-containing organic extractant phase with an hydroxamic acid-containing aqueous phase at a concentration and for a time sufficient to cause the transition metal to reside in the hydroxamic acid-containing aqueous phase.Type: GrantFiled: August 5, 2015Date of Patent: March 5, 2019Assignee: UCHICAGO ARGONNE, LLCInventors: Artem V. Gelis, Michael Alexander Brown
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Publication number: 20180051359Abstract: The invention provides a method for isolating scandium, the method having the steps of dissolving titanium nuclear targets to create a solution; contacting the solution with a resin so as to retain scandium on the resin and generate an eluent containing titanium; contacting the scandium-containing resin with acid of a first concentration to remove impurities from the resin; and contacting the scandium-containing resin with an acid of a second concentration to remove scandium from the resin.Type: ApplicationFiled: August 22, 2016Publication date: February 22, 2018Applicant: UCHICAGO ARGONNE, LLCInventors: Michael Alexander BROWN, David Alan ROTSCH, Jerry A. NOLEN, JR.
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Publication number: 20170037492Abstract: The invention provides a method for extracting transition metals, the method comprising supplying a feedstream containing transition metal, mixing the feedstream with nitric acid for a time and at a concentration sufficient to form an aqueous phase containing the transition metal, combining the aqueous phase with organic extractant phase for a time and at a concentration sufficient to cause the transition metal to reside within the organic extractant phase, and combining the transition metal-containing organic extractant phase with an hydroxamic acid-containing aqueous phase at a concentration and for a time sufficient to cause the transition metal to reside in the hydroxamic acid-containing aqueous phase.Type: ApplicationFiled: August 5, 2015Publication date: February 9, 2017Applicant: UCHICAGO ARGONNE, LLCInventors: Artem V. Gelis, Michael Alexander Brown