Patents by Inventor Michael Ambuhl

Michael Ambuhl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20170368001
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 28, 2017
    Inventors: Colleen Ruegger, Michael Ambuhl
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20170151195
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: February 14, 2017
    Publication date: June 1, 2017
    Inventors: Colleen Ruegger, Michael Ambuhl
  • Organic Compounds
    Publication number: 20160338978
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1 Preceptor modulator.
    Type: Application
    Filed: August 4, 2016
    Publication date: November 24, 2016
    Applicant: Novartis AG
    Inventors: Michael AMBUHL, Jutta BEYER, Begona CARRENO-GOMEZ, Colleen RUEGGER, Stephen VALAZZA
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20160296481
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e. g. a compound comprising a group of formula Y.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 13, 2016
    Applicant: Novartis AG
    Inventors: Colleen RUEGGER, Michael AMBUHL
  • Process for making compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
    Patent number: 9399066
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: July 26, 2016
    Assignee: Novartis AG
    Inventors: Colleen Ruegger, Michael Ambuhl
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20150165046
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: February 25, 2015
    Publication date: June 18, 2015
    Applicant: Novartis AG
    Inventors: Colleen Ruegger, Michael AMBUHL
  • ORGANIC COMPOUNDS
    Publication number: 20140227358
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: April 17, 2014
    Publication date: August 14, 2014
    Applicant: NOVARTIS AG
    Inventors: Michael AMBUHL, Jutta BEYER, Begona CARRENO-GOMEZ, Colleen RUEGGER, Stephen VALAZZA
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20140142192
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: Novartis AG
    Inventors: Colleen RUEGGER, Michael AMBUHL
  • Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
    Patent number: 8673918
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: March 18, 2014
    Assignee: Novartis AG
    Inventors: Colleen Ruegger, Michael Ambühl
  • ORGANIC COMPOUNDS
    Publication number: 20120288559
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: July 19, 2012
    Publication date: November 15, 2012
    Inventors: Michael Ambühl, Jutta Beyer, Begona Carreno-Gomez, Colleen Ruegger, Stephen Valazza
  • Manufacture process
    Patent number: 8252310
    Abstract: The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.
    Type: Grant
    Filed: December 10, 2007
    Date of Patent: August 28, 2012
    Assignee: Novartis AG
    Inventors: Michael Ambühl, Corine Gessier-Vial, Christa Hartmann, Daniel Kaufmann, Ernst Küsters, Ulrich Meier, Andreas Meyer, Nabila Sekkat
  • Manufacture Process
    Publication number: 20120126440
    Abstract: The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.
    Type: Application
    Filed: February 3, 2012
    Publication date: May 24, 2012
    Inventors: Michael Ambühl, Corine Gessier-Vial, Christa Hartmann, Daniel Kaufmann, Ernst Küsters, Ulrich Meier, Andreas Meyer, Nabila Sekkat
  • EMULSION PRECONCENTRATES CONTAINING CYCLOSPORIN OR A MACROLIDE
    Publication number: 20110152201
    Abstract: This invention provides an emulsion, e.g., microemulsion, pre-concentrate comprising a difficultly soluble active agent and a carrier medium. The active agent may, e.g., be a cyclosporin or a macrolide.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 23, 2011
    Inventors: Michael Ambühl, Barbara Lückel, Friedrich Richter, Barbara Häberlin, Armin Meinzer
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20100267675
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: October 9, 2008
    Publication date: October 21, 2010
    Inventors: Colleen Ruegger, Michael Ambuhl
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20100215734
    Abstract: The present invention provides a pharmaceutical composition in solid form comprising a poorly water soluble drug, a solubilizing component, and a surfactant which is semisolid or solid. The poorly soluble drug may e.g. be a cyclosporin or a macrolide.
    Type: Application
    Filed: May 5, 2010
    Publication date: August 26, 2010
    Inventors: Michael Ambühl, Barbara Haeberlin, Barbara Lückel, Armin Meinzer, Olivier Lambert, Laurent Marchal
  • ORGANIC COMPOUNDS
    Publication number: 20100040678
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: September 25, 2007
    Publication date: February 18, 2010
    Inventors: Michael Ambuhl, Jutta Beyer, Begona Carreno-Gomez, Colleen Ruegger, Stephen Valazza
  • ORGANIC COMPOUNDS
    Publication number: 20090312441
    Abstract: A solid pharmaceutical composition comprising a poorly water soluble drug, a polymer which is solid at room temperature, and a disintegrant in an amount of less than 10% by weight, wherein the amounts by weight are based on the total weight of the composition.
    Type: Application
    Filed: December 20, 2005
    Publication date: December 17, 2009
    Applicant: NOVARTIS AG
    Inventors: Michael Ambühl, Dieter Becker, Olivier Lambert, Barbara Lückel
  • Manufacture process
    Publication number: 20080145410
    Abstract: The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.
    Type: Application
    Filed: December 10, 2007
    Publication date: June 19, 2008
    Inventors: Michael Ambuhl, Corine Gessier-Vial, Christa Hartmann, Daniel Kaufmann, Ernst Kusters, Ulrich Meier, Andreas Meyer, Nabila Sekkat
  • Spontaneously Dispersible Pharmaceutical Composition
    Publication number: 20080064760
    Abstract: A spontaneously dispersible pharmaceutical composition comprising a poorly soluble drug and a carrier medium comprising (1) a lipophilic component, (2) a surfactant, and optionally (3) a hydrophilic component, wherein at least one of the components (1) to (3) is solid at room temperature. A particularly useful hydrophilic component in the system is a polymer that is solid at room temperature, e.g., solid PEG.
    Type: Application
    Filed: October 27, 2005
    Publication date: March 13, 2008
    Inventors: Ping Li, Madhusudhan Pudipeddi, Alan Royce, Sara Hynes, Abu Serajuddin, Michael Ambuhl, Barbara Luckel
  • Pharmaceutical compositions
    Publication number: 20060134203
    Abstract: The present invention provides a pharmaceutical composition in solid form comprising a poorly water soluble drug, a solubilizing component, and a surfactant which is semisolid or solid. The poorly soluble drug may e.g. be a cyclosporin or a macrolide.
    Type: Application
    Filed: December 14, 2005
    Publication date: June 22, 2006
    Inventors: Michael Ambuhl, Barbara Haeberlin, Barbara Luckel, Armin Meinzer, Olivier Lambert, Laurent Marchal