Patents by Inventor Michael Anders Godskesen

Michael Anders Godskesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic encoding methods for efficient synthesis of large libraries
    Patent number: 11702652
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: July 18, 2023
    Assignee: NUEVOLUTION A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Søren Nyboe Jakobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sørensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Sløk, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebæk Jensen, Lene Petersen, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Søren Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgard, Alex Haahr Gouliaev, Henrik Pedersen
  • BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
    Publication number: 20220340893
    Abstract: The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
    Type: Application
    Filed: December 3, 2021
    Publication date: October 27, 2022
    Applicant: Nuevolution A/S
    Inventors: Alex Haahr GOULIAEV, Thomas FRANCH, Michael Anders GODSKESEN, Kim Birkebæk JENSEN
  • Bi-functional complexes and methods for making and using such complexes
    Patent number: 11225655
    Abstract: The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
    Type: Grant
    Filed: April 16, 2011
    Date of Patent: January 18, 2022
    Assignee: NUEVOLUTION A/S
    Inventors: Alex Haahr Gouliaev, Thomas Franch, Michael Anders Godskesen, Kim Birkebæk Jensen
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20200216836
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: January 15, 2020
    Publication date: July 9, 2020
    Applicant: NUEVOLUTION A/S
    Inventors: Thomas FRANCH, Mikkel Dybro LUNDORF, Søren Nyboe JAKOBSEN, Eva Kampmann OLSEN, Anne Lee ANDERSEN, Anette HOLTMANN, Anders Holm HANSEN, Anders Malling SØRENSEN, Anne GOLDBECH, Daen de LEON, Ditte Kievsmose KALDOR, Frank Abildgaard SLØK, Gitte Nystrup HUSEMOEN, Johannes DOLBERG, Kim Birkebæk JENSEN, Lene PETERSEN, Mads NØRREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schrøder GLAD, Søren NEVE, Thomas THISTED, Tine Titilola Akinleminu KRONBORG, Christian Klarner SAMS, Jakob FELDING, Per-Ola FRESKGARD, Alex Haahr GOULIAEV, Henrik PEDERSEN
  • Templated molecules and methods for using such molecules
    Patent number: 10669538
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The invention allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: June 2, 2020
    Assignee: NUEVOLUTION A/S
    Inventors: Henrik Pedersen, Alex Haahr Gouliaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Slok, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Thomas Thisted, Per-Ola Freskgard, Anette Holtmann
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20190330618
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: January 22, 2019
    Publication date: October 31, 2019
    Inventors: Thomas FRANCH, Mikkel Dybro LUNDORF, Søren Nyboe JAKOBSEN, Eva Kampmann OLSEN, Anne Lee ANDERSEN, Anette HOLTMANN, Anders Holm HANSEN, Anders Malling SØRENSEN, Anne GOLDBECH, Daen de LEON, Ditte Kievsmose KALDOR, Frank Abildgaard SLØK, Gitte Nystrup HUSEMOEN, Johannes DOLBERG, Kim Birkebæk JENSEN, Lene PETERSEN, Mads NØRREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schrøder GLAD, Søren NEVE, Thomas THISTED, Tine Titilola Akinleminu KRONBORG, Christian Klarner SAMS, Jakob FELDING, Per-Ola FRESKGARD, Alex GOULIAEV, Henrik PEDERSEN
  • Enzymatic encoding methods for efficient synthesis of large libraries
    Patent number: 10287576
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: May 14, 2019
    Assignee: NUEVOLUTION A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Søren Nyboe Jakobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sørensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Sløk, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebæk Jensen, Lene Petersen, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Søren Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgard, Alex Haahr Gouliaev, Henrik Pedersen
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20170247688
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: December 12, 2016
    Publication date: August 31, 2017
    Applicant: NUEVOLUTION A/S
    Inventors: Thomas FRANCH, Mikkel Dybro LUNDORF, Søren Nyboe JACOBSEN, Eva Kampmann OLSEN, Anne Lee ANDERSEN, Anette HOLTMANN, Anders Holm HANSEN, Anders Malling SØRENSEN, Anne GOLDBECH, Daen de LEON, Ditte Kievsmose KALDOR, Frank Abildgaard SLØK, Gitte Nystrup HUSEMOEN, Johannes DOLBERG, Kim Birkebæk JENSEN, Lene PEDERSEN, Mads NØRREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schrøder GLAD, Søren NEVE, Thomas THISTED, Tine Titilola Akinleminu KRONBORG, Christian Klarner SAMS, Jakob FELDING, Per-Ola FRESKGARD, Alex Haahr GOULIAEV, Henrik PEDERSEN
  • TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES
    Publication number: 20170198283
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The invention allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Application
    Filed: October 13, 2016
    Publication date: July 13, 2017
    Inventors: Henrik PEDERSEN, Alex Haahr GOUILAEV, Thomas FRANCH, Christian Klarner SAMS, Eva Kampmann OLSEN, Frank Abilgaard SLOK, Gitte Nystrup HUSEMOEN, Jakob FELDING, Lene HYLDTOFT, Mads NORREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schroder GLAD, Thomas THISTED, Per-Ola FRESKGARD, Anette HOLTMANN
  • Templated molecules and methods for using such molecules
    Patent number: 9688980
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: June 27, 2017
    Assignee: NUEVOLUTION
    Inventors: Henrik Pedersen, Alex Haahr Gouliaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Slok, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Thomas Thisted, Per-Ola Freskgard, Anette Holtmann
  • Enzymatic encoding methods for efficient synthesis of large libraries
    Patent number: 9574189
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: February 21, 2017
    Assignee: Nuevolution A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Søren Nyboe Jacobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sørensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Sløk, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebæ Jensen, Lene Pedersen, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Søren Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgård, Alex Haahr Gouliaev, Henrik Pedersen
  • TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES
    Publication number: 20150315567
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Application
    Filed: December 16, 2014
    Publication date: November 5, 2015
    Inventors: Henrik PEDERSEN, Alex Haahr GOUILAEV, Thomas FRANCH, Christian Klarner SAMS, Eva Kampmann OLSEN, Frank Abilgaard SLOK, Gitte Nystrup HUSEMOEN, Jakob FELDING, Lene HYLDTOFT, Mads NORREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schroder GLAD, Thomas THISTED, Per-Ola FRESKGARD, Anette HOLTMANN
  • Templated molecules and methods for using such molecules
    Patent number: 8932992
    Abstract: The present invention relates to a method for synthesizing templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: January 13, 2015
    Assignee: Nuevolution A/S
    Inventors: Henrik Pedersen, Alex Haahr Gouilaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Sløk, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Thomas Thisted, Per-Ola Freskgård, Anette Holtmann
  • BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
    Publication number: 20130281324
    Abstract: The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
    Type: Application
    Filed: April 16, 2011
    Publication date: October 24, 2013
    Applicant: Nuevolution A/S
    Inventors: Alex Haahr Gouliaev, Thomas Franch, Michael Anders Godskesen, Kim Birkebæk Jensen
  • IAP BINDING COMPOUNDS
    Publication number: 20110230419
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, solvates or prodrugs thereof, that bind to Inhibitor of Apoptosis Proteins (IAPs). The compounds of the invention may be used as diagnostic and therapeutic agents in the treatment of proliferative diseases, such as cancer, for promoting apoptosis in proliferating cells, and for sensitizing cells to inducers of apoptosis. The present invention furthermore provides a polymeric compound of formulas (VI) or (VII), comprising either at least two monomeric units of compounds of formula (I), or at least one monomeric unit of a compound of formula (I) and an entity E. The present invention further relates to pharmaceutical compositions comprising said compounds of formulas (I), (VI), and (VII) and the use of said compounds in medicine.
    Type: Application
    Filed: June 16, 2009
    Publication date: September 22, 2011
    Applicant: Nuevolution A/S
    Inventors: Mikkel Dybro Lundorf, Kim Birkebaek Jenson, Sanne Schrøder Glad, Alek Haahr Gouliaev, Anette Holtmann, Michael Anders Godskesen
  • Templated molecules and methods for using such molecules
    Patent number: 7727713
    Abstract: The present invention relates to a method for synthesizing templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: June 1, 2010
    Assignee: Nuevolution A/S
    Inventors: Henrik Pedersen, Alex Haahr Gouilaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Sløk, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Thomas Thisted, Per-Ola Freskgård, Anette Holtmann
  • TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES
    Publication number: 20100016177
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Application
    Filed: December 9, 2008
    Publication date: January 21, 2010
    Inventors: Henrik Pedersen, Alex Haahr Gouilaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Slok, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Thomas Thisted, Per-Ola Freskgard, Anette Holtmann
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20090264300
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: December 1, 2006
    Publication date: October 22, 2009
    Applicant: Nuevolution A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Soren Nyboe Jacobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sorensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Slok, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebaek Jensen, Lene Pedersen, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Sore Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgard, Alex Haahr Gouliaev, Henrik Pedersen
  • Templated molecules and methods for using such molecules
    Publication number: 20040049008
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Application
    Filed: June 20, 2002
    Publication date: March 11, 2004
    Applicant: Nuevolution A/S
    Inventors: Henrik Pedersen, Alex Haahr Gouilaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Slok, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Thomas Thisted, Per-Ola Freskgard, Anette Holtmann
  • Nucleoside derivatives for library preparation
    Publication number: 20030143561
    Abstract: Nucleoside derivatives as building blocks for templated libraries are described.
    Type: Application
    Filed: June 20, 2002
    Publication date: July 31, 2003
    Applicant: Nuevolution A/S
    Inventors: Henrik Pedersen, Christian Klarner Sams, Frank Abilgaard Slok, Lene Hyldtoft, Michael Anders Godskesen