Abstract: Devices and methods are provided that utilize two adjacent nanopore readers for sequencing of a polymer or a portion thereof.

Abstract: An integrated array of electronic sensing elements outputs a bio-fingerprint of an analyte. System is preferably constructed of as a series of three layers but need not be so arranged. An upper layer defines a fluid volume or analyte chamber; a middle layer contains the sensing elements; and a third layer contains electronic readout elements. The analyte chamber contains an electrolyte and the analyte to be detected. The sensing elements are optimized for maximum detection sensitivity in the minimum response time. The response of each sensing element is read out by a dedicated sensing electrode. Around each electrode is a control ring. The potential of the control ring is set to attract analytes of interest to the sensing elements.

Abstract: A system for measuring a free space electric field includes an ultrahigh impedance antenna positioned in the electric field to generate a signal from the electric field. An amplifier having an input port is provided to amplify the signal. The amplifier generates an input bias current which combines with the signal to create an input potential at the input port. An electrical circuit connects the input port to a ground connection and includes at least one circuit element for controlling the input potential to stabilize the signal at the input port.

Abstract: A system for measuring a free space electric field includes an ultrahigh impedance antenna positioned in the electric field to generate a signal from the electric field. An amplifier having an input port is provided to amplify the signal. The amplifier generates an input bias current which combines with the signal to create an input potential at the input port. An electrical circuit connects the input port to a ground connection and includes at least one circuit element for controlling the input potential to stabilize the signal at the input port.

Abstract: An electronic circuit stabilizes an ultrahigh input impedance amplifier by altering the amplifier's input potential. This input potential includes both the desired input signal and the amplifier's input bias current. With an amplifier having an input port and a guard, both the input port and the guard will have the same input potential. Accordingly, the stabilizing circuit of the present invention provides the input potential at the guard to an electronic device which separates the input signal from the input bias current. This creates a corrective signal. The corrective signal is then used through a feedback path to alter the input potential so that the desired input signal can be fed into the amplifier without adverse consequences from the input bias current.

Abstract: An electronic circuit stabilizes an ultrahigh input impedance amplifier by altering the amplifier's input potential. This input potential includes both the desired input signal and the amplifier's input bias current. With an amplifier having an input port and a guard, both the input port and the guard will have the same input potential. Accordingly, the stabilizing circuit of the present invention provides the input potential at the guard to an electronic device which separates the input signal from the input bias current. This creates a corrective signal. The corrective signal is then used through a feedback path to alter the input potential so that the desired input signal can be fed into the amplifier without adverse consequences from the input bias current.