Patents by Inventor Michael Balazy

Michael Balazy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6903135
    Abstract: The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from, thromboembolic stroke.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: June 7, 2005
    Assignees: Board of Regents, The University of Texas System, New York Medical College, The University of Vermont and State Agricultural College
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy
  • Publication number: 20030176509
    Abstract: The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from, thromboembolic stroke.
    Type: Application
    Filed: February 27, 2003
    Publication date: September 18, 2003
    Applicant: University of Vermont and State Agricultural College
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy
  • Patent number: 6562988
    Abstract: The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: May 13, 2003
    Assignees: Univ. Vermont and State Agricultural College, Univ. of Texas System Board of Regents, New York Medical College
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy
  • Publication number: 20020165262
    Abstract: The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke.
    Type: Application
    Filed: November 9, 2001
    Publication date: November 7, 2002
    Applicant: University of Vermont and State Agricultural College
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy
  • Patent number: 6359158
    Abstract: The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: March 19, 2002
    Assignees: University of Vermont and State Agricultural College, The University of Texas System Board of Regents, New York Medical College
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy
  • Patent number: 6140364
    Abstract: The present invention provides methods and products for inhibiting neutrophil adhesion and neutrophil aggregation. The invention includes a method for treating a subject to inhibit neutrophil adhesion and neutrophil aggregation by administering 16-hydroxyeicosatetraenoic acid (16-HETE) to the subject. 16-HETE is an arachidonic acid metabolite. The invention also includes a pharmaceutical preparation of 16-HETE. Methods and products are also provided for treating thromboembolic stroke. The method involves the administration of 16-HETE in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke. Preferably, the 16-HETE is 16(R)-HETE and the thrombolytic agent is tPA. The product is a pharmaceutical preparation of 16-HETE and a thrombolytic agent and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 26, 1999
    Date of Patent: October 31, 2000
    Assignees: The University of Vermont and State Agricultural College, New York Medical College, Board of Regents The University of Texas System
    Inventors: John R. Falck, Martin M. Bednar, Cordell E. Gross, Michael Balazy
  • Patent number: 5753702
    Abstract: The present invention provides methods and products for inhibiting neutrophil adhesion and neutrophil aggregation. The invention includes a method for treating a subject to inhibit neutrophil adhesion and neutrophil aggregation by administering 16-hydroxyeicosatetraenoic acid (16-HETE) to the subject. 16-HETE is an arachidonic acid metabolite. The invention also includes a pharmaceutical preparation of 16-HETE.
    Type: Grant
    Filed: May 22, 1996
    Date of Patent: May 19, 1998
    Assignee: University of Vermont
    Inventors: Martin M. Bednar, Cordell E. Gross, Michael Balazy, John R. Falck