Abstract: In various aspects and embodiments, the invention provides a nucleic acid molecule comprising a nucleotide sequence encoding a 7?-hydroxysteroid dehydrogenase (7?-HSDH) mutant that catalyzes at least the stereospecific enzymatic reduction of a 7-ketosteroid to the corresponding 7-hydroxysteroid, wherein the mutant has, compared to the wildtype 7?-HSDH of SEQ ID NO:2, a decreased substrate inhibition and/or an altered cofactor usage, and the mutant has, in comparison with the wildtype 7?-HSDH of SEQ ID NO:2, 1 to 15 amino acid additions, substitutions, deletions and/or inversions in the sequence motif VMVGRRE corresponding to positions 36 to 42 of SEQ ID NO:2.

Abstract: A tool for installing a door striker pin. The tool includes a latch portion, a pin positioning portion, and a cover. The latch portion includes a striker pin configured to engage with a latch of a door and an abutment surface configured to engage with a frame member of a cab. The pin positioning portion is coupled to the latch portion. The pin positioning portion defines a striker pin slot extending substantially parallel with the striker pin. The striker pin slot is positioned to align with a striker pin interface for the door. The cover is slidably coupled to the pin positioning portion such that the cover is slidably translatable between a first position where the cover extends across the striker pin slot and a second position where the cover does not extend across the striker pin slot.

Abstract: A method of fabricating a multilayer circuit board is provided which includes forming a layer of a the multilayer circuit board with an internal clearance region having a modified voltage-to-ground clearance of conductive material adjacent to an aperture of the multilayer circuit board. The modified voltage-to-ground clearance of conductive material is based on a configuration of a connector pin to be press-fit connected within the aperture of the multilayer circuit board, and the internal clearance region is enlarged in a direction of greatest normal force outward from the aperture with insertion of the connector pin into the aperture.

Abstract: A housing assembly for a fluid sensor assembly includes a housing having a first and second sensing volumes. A fluid port attached to the housing has a porous membrane covering first and second fluid apertures. The first sensing volume included a vertically-oriented waveguide and is fluidly coupled to an exterior of the housing through the first fluid aperture, where the first aperture port has an area smaller than an area of a cross section of the waveguide. The second sensing volume is coupled to the exterior of the housing through the second fluid aperture, the second fluid aperture having an area larger than a cross section of the second sensing volume. While the first sensing volume and the second sensing volume are both in fluid communication with an exterior of the housing, the fluid port and porous membrane internally isolate the first sensing volume from the second sensing volume.

Abstract: Catalyst for the abatement of ammonia from the exhaust of gasoline internal combustion engines The present invention relates to a catalyst comprising a carrier body having a length L extending between a first end face and a second end face, and differently composed material zones A, B and C arranged on the carrier body, wherein material zone A comprises rhodium and/or nickel and/or cerium; material zone B comprises platinum; and material zone C comprises a zeolite which is able to store ammonia and to catalyze the selective catalytic reduction of NOx.

Abstract: Polyolefin (PO) compositions derived from post-consumer recyclate (PCR) PO based materials having well balanced properties with regards to electric conductivity, impact performance, stiffness, and workability.

Abstract: A radar-based environmental detection system for motor vehicles. The system includes at least one radar sensor for providing location data regarding objects in the environment of the motor vehicle, and including a neural network for converting the location data into an environmental model which represents spatio-temporal object data of the objects. The neural network is conditioned to give priority to outputting environmental models in which at least one predetermined physical relationship between the location data and the object data is satisfied.

Abstract: A vehicle includes a frame, a tractive element coupled to the frame, an engine coupled to the frame and configured to drive the tractive element, and a debris shield coupled to the frame. The debris shield at least partially defines at least one of a left side or a right side of an engine compartment containing the engine. The debris shield includes an outer frame coupled to the frame and defining a ventilation aperture, an inner frame coupled to the outer frame, and a screen extending across the ventilation aperture. The screen extends between the outer frame and the inner frame such that the inner frame limits movement of the screen relative to the outer frame.

Abstract: The invention relates to a motor vehicle seat assembly (10), having motor vehicle seat (12) and having at least one accessory (48) that can be fastened releasably to the motor vehicle seat, wherein the motor vehicle seat has a receiving bushing with insertion opening (30) for the releasable fastening of the accessory, and wherein the accessory has plug-in part (42) that can be inserted into the insertion opening of the receiving bushing, wherein the motor vehicle seat has at least one additional receiving bushing that is arranged offset with respect to the receiving bushing and has additional insertion opening (32), and wherein the insertion opening and the additional insertion opening are assigned insertion directions for plug-in part (44) and for the additional plug-in part that are parallel to one another and are directed in the same direction.

Abstract: A tool for installing a door striker pin includes: a latch engagement section having a first surface, a striker pin extending from the first surface, and an abutment surface that extends generally orthogonal to the first surface; and a pin positioning section coupled to the latch engagement section and including a positioning surface with a striker pin slot formed therethrough that extends in parallel with the striker pin. The striker pin slot is positioned in the positioning surface such that the striker pin slot is aligned with a striker pin installation location when the striker pin of the latch engagement section is engaged with a latch of a door and the abutment surface rests against a frame to which the door is pivotably coupled.

Abstract: The instant disclosure generally relates to a multicomponent composition for coating mammalian or synthetic keratin material and textiles, the composition comprising a first and second components and a third component. The first and second components comprise first and second compounds respectively. Any one or more of the first, second and third components may also comprise pigment microparticles. The first, second and third compounds meld together on keratin material and textiles and especially on hair to form a coating that can be formulated to provide temporary coverage or provide permanent coverage. The multicomponent composition formed and set in situ as a solid linked coating ranges from ready removability to substantially permanent lastingness.

Abstract: The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and a partner drug, processes for the preparation thereof, and their use to treat certain diseases.

Abstract: An adapter for a liquid container of a supply system of a wet process module for the treatment of substrates has a container part for fastening to the liquid container and a channel part for fastening to the supply system. The container part has a central opening and a fastening device for fastening the container part to the liquid container. The channel part has a continuous first channel portion and a continuous second channel portion, the first and the second channel portion each opening into the central opening of the container part.

Abstract: The invention relates to a motor vehicle seat assembly (10), having motor vehicle seat (12) and having at least one accessory (48) that can be fastened releasably to the motor vehicle seat, wherein the motor vehicle seat has a receiving bushing with insertion opening (30) for the releasable fastening of the accessory, and wherein the accessory has plug-in part (42) that can be inserted into the insertion opening of the receiving bushing, wherein the motor vehicle seat has at least one additional receiving bushing that is arranged offset with respect to the receiving bushing and has additional insertion opening (32), and wherein the insertion opening and the additional insertion opening are assigned insertion directions for plug-in part (44) and for the additional plug-in part that are parallel to one another and are directed in the same direction.

Abstract: A mounting system (10) for detachably mounting electronic devices in a motor vehicle, comprising a connecting section (12) for connection to the motor vehicle, with a first holder (30) connected to the connecting section, which first holder (30) has a first holding space (48) and first holding sections (42, 46) for holding a first electronic device (50), with a second holder (52) with a second holding space (54) for holding a second electronic device (56), wherein the second holder can be arranged or is arranged in the first holding space and can be detachably fixed or is detachably fixed to the first holding sections.

Abstract: In one embodiment, a system includes a wafer handling system, processing components, a controller, a virtual assistant, and a natural language processing (NLP) engine. The wafer handling system is configured to hold one or more wafers for processing. The processing components is configured to physically treat the one or more wafers. The controller is configured to operate the processing components. The virtual assistant, in communication with the NLP engine, is configured to receive a user query from a user, understand an intent or context of the user query, and provide a context-specific response to the user query.

Abstract: In one embodiment, a system includes a wafer handling system, processing components, a controller, a virtual assistant, a natural language processing (NLP) engine, and a data-analytics engine. The wafer handling system is configured to hold one or more wafers for processing. The processing components is configured to physically treat the one or more wafers. The controller is configured to operate the processing components. The virtual assistant, in communication with the NLP engine, is configured to receive a user query from a user, understand an intent or context of the user query, and provide a context-specific response to the user query. The data-analytics engine is configured to generate and provide analytical data relating to the user query based on data collected from a plurality of data sources via one or more communication protocols.

Abstract: The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and a partner drug, processes for the preparation thereof, and their use to treat certain diseases.

Abstract: The invention relates to a method for producing a hot-rolled strip composed of a bainitic multi-phase steel and having a Zn—Mg—Al coating, comprising the following steps: melting a steel melt containing (in weight percent): C: 0.04-0.11, Si: <=0.7, Mn: 1.4-2.2, Mo: 0.05-0.5, Al: 0.015-0.1, P: up to 0.02, S: up to 0.01, B: up to 0.006, and at least one element from the group Nb, V, Ti in accordance with the following condition: 0.02<=Nb+V+Ti<=0.20, the remainder being iron including unavoidable steel-accompanying elements resulting from the melting process, casting the steel melt into a preliminary material, in particular a slab or a block or a thin slab, hot rolling the preliminary material into a hot-rolled strip having a final rolling temperature in the range of 800 to 950° C., cooling the hot-rolled strip to a winding temperature less than 650° C., winding the hot-rolled strip at a winding temperature less than 650° C.

Abstract: A steel material for a torsionally stressed component, such as a driveshaft, having a minimum tensile strength of 800 MPs, and the microstructure consists of more than 50 vol. % of bainite, having an alloy with the following composition in wt. %: C: 0.02 to 0.3; Si: up to 0.7; Mn: 1.0 to 3.0; P: max. 0.02; S: max. 0.01; N: max. 0.01; Al: up to 0.1; Cu: up to 0.2; Cr: up to 3.0; Ni: up to 0.3; Mo: up to 0.5; Ti: up to 0.2; V: up to 0.2; Nb: up to 0.1; B: up to 0.01; where 0.02?Nb+V+Ti?0.25, residual iron, and smelting impurities. The steel material is inexpensive and has good torsional fatigue strength when used for a torsionally stressed component. The invention also relates to a method for producing a component made of the material and to such a component.