Patents by Inventor Michael Burbridge

Michael Burbridge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION BETWEEN TRIFLURIDINE/TIPIRACIL HYDROCHLORIDE, AN ANTITUMOR PLATINIUM COMPLEX, AND AN IMMUNE CHECKPOINT MODULATOR
    Publication number: 20200009104
    Abstract: A combination comprising: an FTD-TPI drug, an anti-tumor platinum complex, and an immune checkpoint modulator. Medicinal products containing the same which are useful in treating cancer.
    Type: Application
    Filed: March 16, 2018
    Publication date: January 9, 2020
    Inventors: Jean-Pierre ABASTADO, Nadia AMELLAL, Alain BRUNO, Michael BURBRIDGE, Valérie CATTAN, Catherine LEGER
  • PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20180273538
    Abstract: Compounds of formula (I): wherein R1, R2, W3, W4, A1, and A2 are as defined in the description. Medicinal products containing the same which are useful in treating cancer, neurodegenerative disorders and metabolic disorders.
    Type: Application
    Filed: September 30, 2016
    Publication date: September 27, 2018
    Inventors: Andrea FIUMANA, Nicolas FOLOPPE, Stuart RAY, David WALMSLEY, András KOTSCHY, Michael BURBRIDGE, Francisco Humberto CRUZALEGUI
  • IMIDAZO[4,5-b]PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20180273528
    Abstract: Compounds of formula (I): wherein R1, R2, R3, R4, and R5 are as defined in the description. Medicinal products containing the same which are useful in treating cancer, neurodegenerative disorders and metabolic disorders.
    Type: Application
    Filed: September 30, 2016
    Publication date: September 27, 2018
    Inventors: Balázs BÁLINT, András KOTSCHY, Melinda SIPOS, Csaba WÉBER, Nicolas FOLOPPE, David WALMSLEY, Michael BURBRIDGE, Francisco Humberto CRUZALEGUI
  • ASSOCIATION BETWEEN 3-[(3--2-OXO-2,3-DIHYDRO-1H-INDOL-5-YL)METHYL]-1,3-THIAZOLIDINE-2,4-DIONE AND AN EGFR TYR KINASE INHIBITOR
    Publication number: 20170027952
    Abstract: Association between 3-[(3-{[4-(4-morpholinylmethyl)-1H-pyrrol-2-yl]methylene}-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl]-1,3-thiazolidine-2,4-dione of formula (I): or a Z or E isomer thereof and/or an addition salt thereof with a pharmaceutically acceptable acid or base, and a human epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. Medicinal products containing the same which are useful in treating non-small cell lung cancer.
    Type: Application
    Filed: July 26, 2016
    Publication date: February 2, 2017
    Inventors: Michael BURBRIDGE, Valérie CATTAN, Anne JACQUET-BESCOND
  • Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 8133889
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: March 13, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, legal representative, Pauline Lacoste, legal representative, Imre Fejes, Michael Burbridge, John Hickman, Alain Pierre
  • Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them
    Publication number: 20110034460
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Application
    Filed: August 4, 2010
    Publication date: February 10, 2011
    Applicant: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, Pauline Lacoste, Imre Fejes, Michael Burbridge, John Hickman, Alain Pierre
  • Cyclohexane compounds
    Patent number: 5648382
    Abstract: Compounds of formula (I): ##STR1## wherein: R is selected from the radicals: ##STR2## Y is selected from ##STR3## R.sub.1 represents the radical ##STR4## and A, B, C, D, R.sub.2, R.sub.3 and R.sub.4 are as defined in the description, and also the possible geometric isomers and/or diastereoisomers and/or enantiomers thereof in pure form or in the form of a mixture. The compounds of the present invention have a therapeutic use as a result of their angiogenesis-inhibiting activity.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: July 15, 1997
    Assignee: Adir et Compagnie
    Inventors: David Billington, Isabelle Picard, Ghanem Atassi, Alain Pierre, Michael Burbridge, Nicolas Guilbaud
  • Tetrahydropyran compounds
    Patent number: 5595976
    Abstract: A compound selected from those of formula (I): ##STR1## in which: A either represents --OR.sub.6, and B represents --CH.sub.2 --X,or, together with B and the carbon atom carrying them, forms an oxygen-containing heterocycle selected from oxirane, 2,2-dimethyl[1,3]dioxolane and [1,3]dioxolan-2-one,and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and X are as defined in the description.
    Type: Grant
    Filed: August 30, 1995
    Date of Patent: January 21, 1997
    Assignee: Adir et Compagnie
    Inventors: David Billington, Gilbert Dorey, Pascale Leon, Ghanem Atassi, Alain Pierre, Michael Burbridge, Nicolas Guilbaud