Patents by Inventor Michael C. Griffith

Michael C. Griffith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetracycline compositions
    Patent number: 11944634
    Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: April 2, 2024
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: David C. Griffith, Serge Boyer, Scott Hecker, Michael N. Dudley
  • Triamine derivative melanocortin receptor ligands and methods of using same
    Patent number: 6768024
    Abstract: The invention provides triamine derivative melanocortin receptor ligands of the formula: wherein R1 to R8 and n have the meanings provided herein. The invention further provides methods of using the ligands to alter or regulate the activity of a melanocortin receptor.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: July 27, 2004
    Assignee: Lion Bioscience AG
    Inventors: Karen J. Watson-Straughan, Timothy C. Gahman, Ming Qi, Christa Hamashin, James E. Macdonald, Michael J. Green, Kevin R. Holme, Michael C. Griffith
  • Treatment of erectile dysfunction using isoquinoline compound melanocortin receptor ligands
    Patent number: 6608082
    Abstract: Methods for treating erectile dysfunction using tetrahydroisoquinoline aromatic amines that function as melanocortin receptor ligands.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: August 19, 2003
    Assignee: Lion Bioscience AG
    Inventors: Amaresh Basu, Timothy C. Gahman, Beverly E. Girten, Michael C. Griffith, Curtis C. Hecht, John S. Kiely, Sandra R. Slivka
  • Isoquinoline compound melanocortin receptor ligands and methods of using same
    Patent number: 6127381
    Abstract: The invention relates to melanocortin receptor ligands and methods of using the ligands to alter or regulate the activity of a melanocortin receptor. The invention further relates to tetrahydroisoquinoline aromatic amines that function as melanocortin receptor ligands and as agents for controlling cytokine-regulated physiologic processes and pathologies, and combinatorial libraries thereof.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: October 3, 2000
    Inventors: Amaresh Basu, Timothy C. Gahman, Beverly E. Girten, Michael C. Griffith, Curtis C. Hecht, John S. Kiely, Sandra R. Slivka
  • Isoquinoline derivatives and isoquinoline combinatorial libraries
    Patent number: 5916899
    Abstract: The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.
    Type: Grant
    Filed: October 18, 1996
    Date of Patent: June 29, 1999
    Assignee: Trega Biosciences, Inc.
    Inventors: John S. Kiely, Michael C. Griffith
  • Isoquinoline derivatives and isoquinoline combinatorial libraries
    Patent number: 5874443
    Abstract: The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.
    Type: Grant
    Filed: October 18, 1996
    Date of Patent: February 23, 1999
    Assignee: Trega Biosciences, Inc.
    Inventors: John S. Kiely, Michael C. Griffith