Abstract: The present disclosure is generally directed to the use of compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured or humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a Sortilin protein, e.g., human Sortilin or mammalian Sortilin, and have improved and/or enhanced functional characteristics, in treating and/or delaying progression of a disease or injury in an individual in need thereof.

Abstract: Audio content coded for a reference speaker configuration is downmixed to downmix audio content coded for a specific speaker configuration. One or more gain adjustments are performed on individual portions of the downmix audio content coded for the specific speaker configuration. Loudness measurements are then performed on the individual portions of the downmix audio content. An audio signal that comprises the audio content coded for the reference speaker configuration and downmix loudness metadata is generated. The downmix loudness metadata is created based at least in part on the loudness measurements on the individual portions of the downmix audio content.

Abstract: Embodiments are disclosed for channel-based audio (CBA) (e.g., 22.2-ch audio) to object-based audio (OBA) conversion. The conversion includes converting CBA metadata to object audio metadata (OAMD) and reordering the CBA channels based on channel shuffle information derived in accordance with channel ordering constraints of the OAMD. The OBA with reordered channels is rendered in a playback device using the OAMD or in a source device, such as a set-top box or audio/video recorder. In an embodiment, the CBA metadata includes signaling that indicates a specific OAMD representation to be used in the conversion of the metadata. In an embodiment, pre-computed OAMD is transmitted in a native audio bitstream (e.g., AAC) for transmission (e.g., over HDMI) or for rendering in a source device. In an embodiment, pre-computed OAMD is transmitted in a transport layer bitstream (e.g., ISO BMFF, MPEG4 audio bitstream) to a playback device or source device.

Abstract: Audio content coded for a reference speaker configuration is downmixed to downmix audio content coded for a specific speaker configuration. One or more gain adjustments are performed on individual portions of the downmix audio content coded for the specific speaker configuration. Loudness measurements are then performed on the individual portions of the downmix audio content. An audio signal that comprises the audio content coded for the reference speaker configuration and downmix loudness metadata is generated. The downmix loudness metadata is created based at least in part on the loudness measurements on the individual portions of the downmix audio content.

Abstract: Audio content coded for a reference speaker configuration is downmixed to downmix audio content coded for a specific speaker configuration. One or more gain adjustments are performed on individual portions of the downmix audio content coded for the specific speaker configuration. Loudness measurements are then performed on the individual portions of the downmix audio content. An audio signal that comprises the audio content coded for the reference speaker configuration and downmix loudness metadata is generated. The downmix loudness metadata is created based at least in part on the loudness measurements on the individual portions of the downmix audio content.

Abstract: At least a first cryptogram and a second cryptogram are transmitted from a payment device reader component to a terminal component. A message including at least the first cryptogram and the second cryptogram is transmitted from the terminal component to an issuer of a payment device presented to the reader component, through a payment network. A message is obtained from the issuer, corresponding to authentication, by the issuer, of the payment device (and optionally the owner of the payment device) presented to the reader component, based at least on the first cryptogram and the second cryptogram. The payment network is configured in accordance with at least one of (i) a standard, and (ii) a specification, which normally employs only a single cryptogram for the message and the authentication. Apparatuses and computer program products are also disclosed.

Abstract: Secure establishment of a key associated with a first facility identifier is facilitated. The key is shared between a device and an operator of a first facility, via a public key management infrastructure of a payment system operating according to the payment standard, during a first transaction, substantially in accordance with the payment standard, between the device and the first facility. Controlling access to a first facility is facilitated, via the device, using the key associated with the first facility identifier, substantially without reference to an issuer of the device and substantially without use of asymmetric keys of the device, during a plurality of subsequent transactions, substantially in accordance with the payment standard, between the device and the first facility.

Abstract: A wagering game system and its operations are described herein. In some embodiments, the operations can include presenting a wagering game on a display device of a wagering game machine. The operations can also include detecting head movements and facial gestures of a player of the wagering game via a video capture device of the wagering game machine, and generating player input data based on the head movements and facial gestures of the player. The operations can further include modifying wagering game content based on the player input data associated with the head movements and facial gestures of the player, and presenting results of the wagering game on the display device of the wagering game machine.

Abstract: Techniques are provided for transaction adjustment. A payment device, having an offline balance, is presented to an offline terminal in connection with a putative transaction. If an irregularity with the putative transaction is detected, the offline balance is adjusted responsive to the detection. In one aspect of the invention, such adjustment can be carried out, via offline-terminal interaction, substantially without the use of a security module and cryptographic keys in the offline terminal.

Abstract: A wagering game system and its operations are described herein. In some embodiments, the operations can include presenting a wagering game on a display device of a wagering game machine. The operations can also include detecting head movements and facial gestures of a player of the wagering game via a video capture device of the wagering game machine, and generating player input data based on the head movements and facial gestures of the player. The operations can further include modifying wagering game content based on the player input data associated with the head movements and facial gestures of the player, and presenting results of the wagering game on the display device of the wagering game machine.

Abstract: A wagering game system and its operations are described herein. In embodiments, the operations can include presenting a skill-based wagering game on a wagering game machine. The skill-based wagering game can have a limited winnable award amount for the skill-based wagering game. The operations can also include tracking skilled game goals that a player accomplishes during the skill-based wagering game and awarding the player from the limited winnable award amount. The operations can also include determining a surplus amount that was not earned from the limited winnable award amount, and awarding some, or all, of the surplus amount during subsequent activity. In some embodiments, the operations can also include allocating the surplus amount to wagering game pools, distributing the surplus amount as tokens based on triggered activities, and presenting game modifiers that enable players to enhance performance in a skill-based game.

Abstract: Techniques are provided for transaction adjustment. A payment device, having an offline balance, is presented to an offline terminal in connection with a putative transaction. If an irregularity with the putative transaction is detected, the offline balance is adjusted responsive to the detection. In one aspect of the invention, such adjustment can be carried out, via offline-terminal interaction, substantially without the use of a security module and cryptographic keys in the offline terminal.

Abstract: At least a first cryptogram and a second cryptogram are transmitted from a payment device reader component to a terminal component. A message including at least the first cryptogram and the second cryptogram is transmitted from the terminal component to an issuer of a payment device presented to the reader component, through a payment network. A message is obtained from the issuer, corresponding to authentication, by the issuer, of the payment device (and optionally the owner of the payment device) presented to the reader component, based at least on the first cryptogram and the second cryptogram. The payment network is configured in accordance with at least one of (i) a standard, and (ii) a specification, which normally employs only a single cryptogram for the message and the authentication. Apparatuses and computer program products are also disclosed.

Abstract: Techniques are provided for transaction adjustment. A payment device, having an offline balance, is presented to an offline terminal in connection with a putative transaction. If an irregularity with the putative transaction is detected, the offline balance is adjusted responsive to the detection. In one aspect of the invention, such adjustment can be carried out, via offline-terminal interaction, substantially without the use of a security module and cryptographic keys in the offline terminal.

Abstract: A wagering game system and its operations are described herein. In embodiments, the operations can include presenting a skill-based wagering game on a wagering game machine. The skill-based wagering game can have a limited winnable award amount for the skill-based wagering game. The operations can also include tracking skilled game goals that a player accomplishes during the skill-based wagering game and awarding the player from the limited winnable award amount. The operations can also include determining a surplus amount that was not earned from the limited winnable award amount, and awarding some, or all, of the surplus amount during subsequent activity. In some embodiments, the operations can also include allocating the surplus amount to wagering game pools, distributing the surplus amount as tokens based on triggered activities, and presenting game modifiers that enable players to enhance performance in a skill-based game.

Abstract: Secure establishment of a key associated with a first facility identifier is facilitated. The key is shared between a device and an operator of a first facility, via a public key management infrastructure of a payment system operating according to the payment standard, during a first transaction, substantially in accordance with the payment standard, between the device and the first facility. Controlling access to a first facility is facilitated, via the device, using the key associated with the first facility identifier, substantially without reference to an issuer of the device and substantially without use of asymmetric keys of the device, during a plurality of subsequent transactions, substantially in accordance with the payment standard, between the device and the first facility.

Abstract: Techniques are provided for transaction adjustment. A payment device, having an offline balance, is presented to an offline terminal in connection with a putative transaction. If an irregularity with the putative transaction is detected, the offline balance is adjusted responsive to the detection. In one aspect of the invention, such adjustment can be carried out, via offline-terminal interaction, substantially without the use of a security module and cryptographic keys in the offline terminal.

Abstract: A suspension strut having a piston tube containing a floating piston, slidable within a cylinder tube. A collar is fixed to the inner surface of the cylinder tube and contains a tapered wear ring. As the strut expands by extending the piston tube relative to the cylinder tube, the tapered wear band slides over valve orifices in the outer surface of the piston tube, gradually cutting off fluid flow from the annular space between the two tubes into an end cavity of the strut, thus increasing damping and reducing the likelihood of metal to metal contact at full strut extension. This reduces shock loads on the strut for smoother vehicle operation and increased component life.

Abstract: A suspension strut having a piston tube containing a floating piston, slidable within a cylinder tube. A collar is fixed to the inner surface of the cylinder tube and contains a tapered wear ring. As the strut expands by extending the piston tube relative to the cylinder tube, the tapered wear band slides over valve orifices in the outer surface of the piston tube, gradually cutting off fluid flow from the annular space between the two tubes into an end cavity of the strut, thus increasing damping and reducing the likelihood of metal to metal contact at full strut extension. This reduces shock loads on the strut for smoother vehicle operation and increased component life.

Abstract: A method and apparatus for equalizing high frequency video signals is disclosed. A video signal to be equalized is received at an input terminal of a network and an equalized video signal is provided from an output of an operational amplifier to an output terminal of the network. The equalized video signal is fedback to one input of the operational amplifier. The video signal to be equalized is coupled to another input of the operational amplifier and is also coupled to respective ones of a plurality of alterable circuit elements such as varactor diodes, which function to mitigate distortions to the frequency response characteristic of the video signal to be equalized by cancelling the effect thereon by the video signal to be equalized.