Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Abstract: The present invention is directed to the creation of macroscopic materials and objects comprising aligned nanotube segments. The invention entails aligning single-wall carbon nanotube (SWNT) segments that are suspended in a fluid medium and then removing the aligned segments from suspension in a way that macroscopic, ordered assemblies of SWNT are formed. The invention is further directed to controlling the natural proclivity of nanotube segments to self assemble into ordered structures by modifying the environment of the nanotubes and the history of that environment prior to and during the process. The materials and objects are “macroscopic” in that they are large enough to be seen without the aid of a microscope or of the dimensions of such objects.

Abstract: A pipe insulation system includes a tubular core of fibrous insulation and a flexible closed cell foam layer overlaying the core and forming an outer surface of the system. The tubular core has a first longitudinal slit extending completely through the wall of the core and a second longitudinal slit in the inner surface of the tubular core, opposite the first slit, that forms a hinge permitting the tubular core to be opened and closed to place the system about a pipe. Preferably, the foam layer has a water vapor permeance rating of 0.02 perms or less and the pipe insulation system includes a seal for sealing the first slit so that an outer surface layer of the sealed system formed by the foam layer and seal has a water vapor permeance rating of 0.02 perms or less.

Abstract: A pipe insulation system includes a tubular core of fibrous insulation that is coated with a pliable polymer. The coated tubular core has a first longitudinal slit extending completely through the wall of the core and a second longitudinal slit in the inner surface of the tubular core that is opposite the first slit and forms a hinge that permits the tubular core to be opened and closed to place the coated tubular core about a pipe. Preferably, the coating has a water vapor permeance rating of 0.02 perms or less and the system includes a seal for sealing the first slit so that an outer surface layer of the sealed coated tubular core formed by the coating and seal has a water vapor permeance rating of 0.02 perms or less for use on cold pipe systems.