Abstract: A progressive compression driven flow cartridge for analyzing liquids is coupled with convenient sampling methods for different applications. A one-step device provides for direct sample collection upon a sample pad annexed to the cartridge. The sample pad can deliver sample to the test strips, while saving a portion of the sample pad for further laboratory confirmation use. If the sample collecting pad is not suitable to collect the sample, such as the case of biological substances inside the human body, such as within the nose or throat, a two-step device can include a long-arm swab applicator and a specialized chamber in which some amount of liquid can dissolve biological substances as specimen. The specimen can then be transferred onto the cartridge, either by application to the sample pad, or into the device through a sample window. Each method provides a qualitative analysis much faster than traditional rapid diagnostic devices.

Abstract: A test device uses driven flow technology in a simplified testing format, such as dip format, to provide a rapid diagnostic test device that shortens the interpretation time of the test result to less than one minute and minimizes manufacturing costs. The test device shortens the distance between the opening on the front side housing and the conjugate pad without squeezing the sample pad and without requiring a separate component, such as a cap, to squeeze the sample pad. The test device utilizes a single, integral housing made from, for example, a flexible transparent material, such as polyethylene terephthalate (PET) that integrates the traditional base and top, or inner and outer tubes, into one to save the manufacturing costs.

Abstract: A progressive compression test cartridge that is adapted with driven flow technology that can be coupled with a digital electronic device to make the test reading result more reliable quantitatively than visual interpretation. The test cartridge can provide test results typically in one minute or less. The test cartridge can accept a sample via a droplet or a stream sampling method. In the stream sampling method, the open end of the test cartridge allows the sample pad of the test strip to be exposed to the stream of fluid. A refracting pad on the base of the test cartridge can refract the original stream vector partially along the sample pad then continue flowing to elute and release the nanoparticles from the conjugate pad onto the membrane which is pre-coated with reactant(s). Collimated compression bars can prevent flooding sample by restricting the top and bottom surface of the conjugated pad.

Abstract: A rapid diagnostic test device uses driven flow technology to significantly expedite the testing time of a sample. The rapid diagnostic test device can be used to analyze liquids, such as some body fluids, by using labeled molecular affinity binding, such as immunochromatography. The test device can detect an analyte, such as an antibody or antigen, which may indicate a particular condition, the presence of a particular drug, or the like. The device includes an inner member that receives the body fluid. Dripping holes in the inner member, or a sloped surface, creates a stream force of the body fluid against the sample pad of the test strip. A portion of the stream force of the body fluid is directed upward toward the conjugate pad to push the antibody/body fluid sample onto the membrane of the test strip.

Abstract: A rapid diagnostic test device uses driven flow technology to significantly expedite the testing time of a sample. The rapid diagnostic test device can be used to analyze liquids, such as some body fluids, by using labeled molecular affinity binding, such as immunochromatography. The test device can detect an analyte, such as an antibody or antigen, which may indicate a particular condition, the presence of a particular drug, or the like. The device includes a cover and base that combine to form an internal cavity for receiving a test strip. Compression bars in the cover and a compression cushion in the base sandwich a conjugate pad of the test strip to accelerate chemical mixtures to flow from the conjugate pad of the test strip toward fixed sites along the strip from which readings are taken.

Abstract: A rapid diagnostic test device uses driven flow technology to significantly expedite the testing time of a sample. The rapid diagnostic test device can be used to analyze liquids, such as some body fluids, by using labeled molecular affinity binding, such as immunochromatography. The test device can detect an analyte, such as an antibody or antigen, which may indicate a particular condition, the presence of a particular drug, or the like. The device includes a top and bottom that combine to form a fluid channel through which a fluid is forced from a fluid collector. A press pad in the device may press against a press pad on a test strip to accelerate chemical mixtures to flow from the conjugate color pad of the test strip toward fixed sites along the strip from which readings are taken.

Abstract: A three-in-one apparatus for analyzing liquids, such as some body fluids, uses labeled molecular affinity binding, such as immunochromatography. The multi-functional diagnostic test device can detect an analyte, such as an antibody or antigen, which may indicate a particular condition. The multi-functional diagnostic test device provides multi-functional formats to apply in multiple different sampling methods, including the “dip”, “cassette” and “collection” formats. The diagnostic test device can accommodate a plurality of test strips, such as 18 test strips for analyzing up to 90 analytes.