Patents by Inventor Michael Christopher Kuczewski

Michael Christopher Kuczewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL BROTH CLARIFICATION AND HOST CELL PROTEIN REMOVAL
    Publication number: 20110184154
    Abstract: The present invention relates to a method for clarification of, and removal of host cell proteins from, a cell broth consisting essentially of viable cells, a culture medium and a secreted desired biological substance having an overall positive charge in the cell broth by contacting the cell broth with a particulate anion exchanger, allowing an adequate incubation time to result in formation of a cell pellet and a supernatant layer, separating the resulting cell pellet from the supernatant layer. The present invention further relates to a method for the recovery of a secreted desired biological substance from the cell broth by extracting the secreted desired biological substance from the supernatant layer.
    Type: Application
    Filed: April 9, 2011
    Publication date: July 28, 2011
    Applicant: PERCIVIA LLC
    Inventors: Grigorios Zarbis-Papastoitsis, Michael Christopher Kuczewski, Emily Belcher Schirmer