Patents by Inventor Michael D. Dake
Michael D. Dake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9180081Abstract: Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.Type: GrantFiled: March 3, 2006Date of Patent: November 10, 2015Assignee: REVANCE THERAPEUTICS, INC.Inventors: Michael D. Dake, Jacob M. Waugh
-
Publication number: 20150313626Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.Type: ApplicationFiled: July 13, 2015Publication date: November 5, 2015Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu J. Patel, David M. Williams, William P. Witort
-
Patent number: 9107681Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.Type: GrantFiled: September 10, 2013Date of Patent: August 18, 2015Assignee: W. L. Gore Associates, Inc.Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu J. Patel, David M. Williams, William P. Witort
-
Publication number: 20150196593Abstract: Methods of altering properties of tissues, by providing an effective modifying amount of zinc, which may be in the form of zinc ions. This is accomplished through the use of topical compositions containing one or more zinc-containing components such as salts and/or other zinc compounds or complexes, particularly zinc acetate. Altering properties of tissues includes increasing or decreasing fatty tissue, increasing or decreasing epidermal thickness, increasing elastin content, and preventing or treating gum regression or atrophy. Also disclosed is the provision of a contact lens coated with a zinc-containing material, to improve vision by increasing elastin content of the lens of the eye through release of zinc ions.Type: ApplicationFiled: January 23, 2015Publication date: July 16, 2015Inventors: Pamela Cifra, Michael D. Dake, Christopher Elkins, Jacob M. Waugh
-
Patent number: 8974774Abstract: Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non-protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternately, the compositions can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.Type: GrantFiled: March 3, 2005Date of Patent: March 10, 2015Assignee: Revance Therapeutics, Inc.Inventors: Michael D. Dake, Jacob M. Waugh
-
Patent number: 8962548Abstract: Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, including nucleic acids and therapeutic proteins including insulin, larger therapeutic proteins such as botulinum toxin and other biologically active agents such as a therapeutic protein which does not therapeutically alter blood glucose levels, a therapeutic nucleic acid-based agent, a non-protein non-nucleic acid therapeutic agent such as an antifungal agent or alternately an agent for immunization. The compositions can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.Type: GrantFiled: March 3, 2005Date of Patent: February 24, 2015Assignee: Revance Therapeutics, Inc.Inventors: Jacob M. Waugh, Michael D. Dake
-
Patent number: 8709067Abstract: The present invention provides, in a first aspect a bifurcated stent for use in juxtaposition with an angelogical bifurcation. The bifurcated stent comprises a proximal portion adapted to be disposed within a blood vessel in juxtaposition with a bifurcation, a first distal stent portion adapted to extend across the bifurcation into one of the branched blood vessels, and a second distal stent portion adapted to allow blood to flow from the proximal portion into the other branch blood vessel. The invention also embraces a bifurcated prosthesis including such a bifurcated stent and a tubular graft layer formed from a biocompatible fabric in juxtaposition with the stent. In a second aspect of the invention there is provided a stent connection for joining two stents one to the other to define a continuous lumen through the two stents. Said stent connection comprises a first stent including a male engaging portion which can be compressed radially inwardly and a second stent including a female cooperating portion.Type: GrantFiled: August 31, 2012Date of Patent: April 29, 2014Assignee: Lifeshield Sciences, LLCInventors: Andrew H. Cragg, Claude Mialhe, George Goicoechea, John Hudson, Michael D. Dake
-
Publication number: 20140012252Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.Type: ApplicationFiled: September 10, 2013Publication date: January 9, 2014Applicant: W. L. Gore & Associates, Inc.Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu J. Patel, David M. Williams, William P. Witort
-
Patent number: 8556921Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.Type: GrantFiled: November 11, 2010Date of Patent: October 15, 2013Assignee: W. L. Gore & Associates, Inc.Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu Jagdish Patel, David M. Williams, William P. Witort
-
Publication number: 20130211506Abstract: A device for treating disease along a main vessel and at least one branch vessel extending from the main vessel includes a branch member for deployment in the branch vessel, the branch member having a branch lumen; and a main body for deployment in the main vessel. The main body has a generally tubular wall extending generally longitudinally between opposite first and second ends. The wall has an internal surface defining a main lumen and an opposite outer surface. The wall has a recessed portion that is recessed relative to the outer surface of the wall and positioned between the first and second ends of the main body. The main body has an opening formed in the recessed portion of the wall for receiving the branch member therethrough such that the branch lumen is in fluid communication with the main lumen.Type: ApplicationFiled: August 13, 2012Publication date: August 15, 2013Inventors: Michael D. Dake, Joshua J. Lovekamp, Michael C. Nilson, Edward E. Shaw
-
Publication number: 20130123904Abstract: The present disclosure provides a bifurcated stent for use in juxtaposition with an angiological bifurcation. The disclosure provides a bifurcated stent that includes a proximal portion adapted to be disposed within a blood vessel in juxtaposition with a bifurcation, a first distal stent portion adapted to extend across the bifurcation into one of the branched blood vessels, and a second distal stent portion adapted to allow blood to flow from the proximal portion into the other branch blood vessel. The disclosure also provides a bifurcated prosthesis including such a bifurcated stent and a tubular graft layer formed from a biocompatible fabric in juxtaposition with the stent. The disclosure also provides a stent joining means for joining two stents one to the other to define a continuous lumen through the two stents.Type: ApplicationFiled: August 31, 2012Publication date: May 16, 2013Applicant: Scimed Life Systems, Inc.Inventors: Andrew H. Cragg, Claude Mialhe, George Goicoechea, John Hudson, Michael D. Dake
-
Patent number: 8404249Abstract: A composition for topical application of a botulinum toxin (including botulinum toxin derivatives) comprises a botulinum toxin and a carrier comprising a polymeric backbone comprising a long-chain polypeptide or nonpeptidyl polymer having attached positively charged branching or “efficiency” groups. The invention also relates to methods for reducing muscle paralysis and other conditions that may be treated with a botulinum toxin, particularly paralysis of subcutaneous, and most particularly, facial, muscles, by topically applying an effective amount of the botulinum toxin and carrier, in conjunction, to the subject's skin or epithelium. Kits for administration are also described.Type: GrantFiled: March 3, 2005Date of Patent: March 26, 2013Assignee: Revance Therapeutics, Inc.Inventors: Michael D. Dake, Jacob M. Waugh
-
Patent number: 8398997Abstract: A composition for topical application of a botulinum toxin (including botulinum toxin derivatives) comprises a botulinum toxin and a carrier comprising a polymeric backbone comprising a long-chain polypeptide or nonpeptidyl polymer having attached positively charged branching or “efficiency” groups. The invention also relates to methods for reducing muscle paralysis and other conditions that may be treated with a botulinum toxin, particularly paralysis of subcutaneous, and most particularly, facial, muscles, by topically applying an effective amount of the botulinum toxin and carrier, in conjunction, to the subject's skin or epithelium. Kits for administration are also described.Type: GrantFiled: March 3, 2005Date of Patent: March 19, 2013Assignee: Revance Therapeutics, Inc.Inventors: Michael D. Dake, Jacob M. Waugh
-
Patent number: 8192482Abstract: A stent is provided comprising a plurality of hoops aligned along a common axis, wherein each of the hoops is oriented in a plane substantially perpendicular to the longitudinal axis of the stent. Each of the hoops includes a plurality of elongate elements joined to one another and forming apices that point in a direction along the axis of the stent. The stent also comprises means for securing an apex of one hoop to a juxtaposed apex of a neighboring hoop.Type: GrantFiled: October 15, 2001Date of Patent: June 5, 2012Assignee: Scimed Life Systems, Inc.Inventors: George Goicoechea, John Hudson, Andrew H. Cragg, Claude Mialhe, Michael D. Dake
-
Publication number: 20120065131Abstract: The invention relates to the transdermal application of oligopeptides for reducing synaptic transmission in tissues of an animal. In one aspect, this invention relates to compositions comprising an oligopeptide and optionally a carrier comprising a positively charged “backbone” having positively charged branching or “efficiency” groups, as described herein. Most preferably the positively charged carrier is a long-chain positively charged polypeptide or a positively charged nonpeptidyl polymer, for example, a polyalkyleneimine. The invention further relates methods for producing a biologic effect of reducing synaptic transmission in a tissue by topically applying an effective amount of such a composition, preferably to the skin, of a subject or patient in need of such treatment.Type: ApplicationFiled: August 29, 2011Publication date: March 15, 2012Applicant: Revance Therapeutics, Inc.Inventors: Michael D. Dake, Jacob M. Waugh
-
Patent number: 8092788Abstract: Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non-protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternately, the compositions can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.Type: GrantFiled: March 3, 2005Date of Patent: January 10, 2012Assignee: Revance Therapeutics, Inc.Inventors: Michael D. Dake, Jacob M. Waugh
-
Patent number: 8022179Abstract: The invention relates to the transdermal application of oligopeptides for reducing synaptic transmission in tissues of an animal. In one aspect, this invention relates to compositions comprising an oligopeptide and optionally a carrier comprising a positively charged “backbone” having positively charged branching or “efficiency” groups, as described herein. Most preferably the positively charged carrier is a long-chain positively charged polypeptide or a positively charged nonpeptidyl polymer, for example, a polyalkyleneimine. The invention further relates methods for producing a biologic effect of reducing synaptic transmission in a tissue by topically applying an effective amount of such a composition, preferably to the skin, of a subject or patient in need of such treatment.Type: GrantFiled: March 3, 2006Date of Patent: September 20, 2011Assignee: Revance Therapeutics, Inc.Inventors: Michael D. Dake, Jacob M. Waugh
-
Publication number: 20110144672Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.Type: ApplicationFiled: November 11, 2010Publication date: June 16, 2011Inventors: Cody L. Bliss, Edward H. Cully, Michael D. Dake, Joel M. Greene, Joshua J. Lovekamp, Michael C. Nilson, Himanshu Jagdis Patel, David M. Williams, William P. Witort
-
Patent number: 7942919Abstract: The invention comprises: An introducer for delivering into the vasculature a straight or bifurcated stent or prosthesis; a method for delivering into the vasculature a straight or bifurcated stent or prosthesis; a method of treating and angeological disease using a bifurcated stent; an endoluminal stent having perpendicular hoop members, each hoop member formed of wire in a sinuous configuration, at least some of juxtaposed apices in neighboring hoops being secured to one another, such stents also forming axially aligned segments in straight stents, and segments of bifurcated stents in particular embodiments. Certain embodiments of such stents also include barbs, fabric covering and radiopaque markers.Type: GrantFiled: February 23, 2004Date of Patent: May 17, 2011Assignee: Scimed Life Systems, Inc.Inventors: George Goicoechea, Claude Mialhe, John Hudson, Andrew H. Cragg, Michael D. Dake
-
Patent number: 7905914Abstract: The invention comprises: An introducer for delivering into the vasculature a straight or bifurcated stent or prosthesis; a method for delivering into the vasculature a straight or bifurcated stent or prosthesis; a method of treating and angeological disease using a bifurcated stent; an endoluminal stent having perpendicular hoop members, each hoop member formed of wire in a sinuous configuration, at least some of juxtaposed apices in neighboring hoops being secured to one another, such stents also forming axially aligned segments in straight stents, and segments of bifurcated stents in particular embodiments. Certain embodiments of such stents also include barbs, fabric covering and radiopaque markers.Type: GrantFiled: February 23, 2004Date of Patent: March 15, 2011Assignee: Scimed Life Systems, Inc.Inventors: George Goicoechea, Claude Mialhe, John Hudson, Andrew H. Cragg, Michael D. Dake