Patents by Inventor Michael D. Tennant

Michael D. Tennant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adiponectin gene therapy
    Patent number: 6967018
    Abstract: Adiponectin cDNA was cloned into AAV serotypes 1, 2, and 5-based expression vectors. Virions containing these vectors were administered to the livers of rat subjects via portal vein injection. A single injection of 6×1011 virions of the vector caused a sustained and statistically significant reduction in body weight of the treated animals compared to the control animals. This occurred in the absence of side effects. Compared to control animals, the subject rats also exhibited reduced adipose tissue mass, reduced appetite, improved insulin sensitivity, and improved glucose tolerance.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: November 22, 2005
    Assignee: Applied Genetic Technologies Corporation
    Inventors: Sergei Zolotukhin, Michael D. Tennant
  • Adiponectin gene therapy
    Publication number: 20030147855
    Abstract: Adiponectin cDNA was cloned into AAV serotypes 1, 2, and 5-based expression vectors. Virions containing these vectors were administered to the livers of rat subjects via portal vein injection. A single injection of 6×1011 virions of the vector caused a sustained and statistically significant reduction in body weight of the treated animals compared to the control animals. This occurred in the absence of side effects. Compared to control animals, the subject rats also exhibited reduced adipose tissue mass, reduced appetite, improved insulin sensitivity, and improved glucose tolerance.
    Type: Application
    Filed: January 13, 2003
    Publication date: August 7, 2003
    Inventors: Sergei Zolotukhin, Michael D. Tennant