Patents by Inventor Michael Dalgaard Mikkelsen

Michael Dalgaard Mikkelsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant Production of Steviol Glycosides
    Publication number: 20240110215
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: September 20, 2023
    Publication date: April 4, 2024
    Inventors: Ganesh M. Kishore, Michael Motion, Paula M. Hicks, Jorgen Hansen, Jens Houghton Larsen, Esben Halkjaer Hansen, Michael Dalgaard Mikkelsen, Sabina Tavares, Charlotte Blom
  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20240026409
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: August 16, 2023
    Publication date: January 25, 2024
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Production of steviol glycoside in recombinant hosts
    Patent number: 11807888
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: November 7, 2023
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • METHODS FOR IMPROVED PRODUCTION OF REBAUDIOSIDE D AND REBAUDIOSIDE M
    Publication number: 20230279459
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Application
    Filed: November 3, 2022
    Publication date: September 7, 2023
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20230212630
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: August 30, 2022
    Publication date: July 6, 2023
    Inventors: Helene Lunde Robertson, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20230033436
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: April 29, 2021
    Publication date: February 2, 2023
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Methods for improved production of Rebaudioside D and Rebaudioside M
    Patent number: 11530431
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: December 20, 2022
    Assignee: EVOLVA SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11466302
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: October 11, 2022
    Assignee: EVOLVA SA
    Inventors: Helene Lunde Robertsen, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20220127655
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: September 1, 2021
    Publication date: April 28, 2022
    Inventors: Veronique Douchin, Michael Dalgaard Mikkelsen, Iben Møller-Hansen
  • Recombinant Production of Steviol Glycosides
    Publication number: 20220073960
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: July 12, 2021
    Publication date: March 10, 2022
    Inventors: Ganesh M. Kishore, Michael Motion, Paula M. Hicks, Jorgen Hansen, Jens Hougton-Larsen, Esben Halkjaer Hansen, Michael Dalgaard Mikkelsen, Sabina Tavares, Charlotte Blom, Sr.
  • Efficient Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20220017932
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.
    Type: Application
    Filed: April 29, 2021
    Publication date: January 20, 2022
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS
    Publication number: 20210198711
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: October 12, 2020
    Publication date: July 1, 2021
    Inventors: Veronique DOUCHIN, Michael DALGAARD MIKKELSEN, Iben MØLLER-HANSEN
  • Production of steviol glycoside in recombinant hosts
    Patent number: 11041183
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: June 22, 2021
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Efficient production of steviol glycosides in recombinant hosts
    Patent number: 11021727
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: June 1, 2021
    Assignee: EVOLVA SA
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20200392552
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: February 26, 2020
    Publication date: December 17, 2020
    Inventors: Helene Lunde Robertsen, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • Production of steviol glycosides in recombinant hosts
    Patent number: 10837041
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: November 17, 2020
    Assignee: EVOLVA SA
    Inventors: Veronique Douchin, Michael Dalgaard Mikkelsen, Iben Møller-Hansen
  • METHODS FOR IMPROVED PRODUCTION OF REBAUDIOSIDE D AND REBAUDIOSIDE M
    Publication number: 20200308617
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Application
    Filed: February 24, 2020
    Publication date: October 1, 2020
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Production of Steviol Glycosides in Microorganisms
    Publication number: 20200140912
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express novel recombinant genes encoding steviol biosynthetic enzymes and UDP-glycosyltransferases (UGTs). Such microorganisms plants, or plant cells can produce steviol or steviol glycosides, e.g., rubusoside or Rebaudioside A, which can be used as natural sweeteners in food products and dietary supplements.
    Type: Application
    Filed: July 2, 2019
    Publication date: May 7, 2020
    Inventors: Ganesh M. Kishore, Michael Motion, Paula M. Hicks, Jorgen Hansen, Jens Houghton-Larsen, Esben Halkjaer Hansen, Michael Dalgaard Mikkelsen, Sabina Tavares, Charlotte Blom
  • Production of steviol glycosides in recombinant hosts
    Patent number: 10612064
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: April 7, 2020
    Assignee: Evolva SA
    Inventors: Helene Lunde Robertson, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • Methods for improved production of rebaudioside D and rebaudioside M
    Patent number: 10612066
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 7, 2020
    Assignee: Evolva SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks