Patents by Inventor Michael Donnenberg

Michael Donnenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered type IV pilin of
    Patent number: 9802988
    Abstract: The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: October 31, 2017
    Assignee: University of Maryland, Baltimore
    Inventor: Michael Donnenberg
  • Engineered type IV pilin of
    Patent number: 9310381
    Abstract: The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: April 12, 2016
    Assignee: University of Maryland, Baltimore
    Inventor: Michael Donnenberg
  • Engineered Type IV Pilin of Clostridium difficile
    Publication number: 20140227314
    Abstract: The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
    Type: Application
    Filed: April 23, 2014
    Publication date: August 14, 2014
    Applicant: University of Maryland, Baltimore
    Inventor: Michael Donnenberg
  • Engineered Type IV Pilin of Clostridium difficile
    Publication number: 20130337003
    Abstract: The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
    Type: Application
    Filed: August 23, 2013
    Publication date: December 19, 2013
    Applicant: University of Maryland, Baltimore
    Inventor: Michael Donnenberg
  • Engineered type IV pilin of
    Patent number: 8518415
    Abstract: The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: August 27, 2013
    Assignee: University of Maryland, Baltimore
    Inventor: Michael Donnenberg
  • Engineered Type IV Pilin of Clostridium difficile
    Publication number: 20120064105
    Abstract: The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
    Type: Application
    Filed: May 20, 2010
    Publication date: March 15, 2012
    Applicant: University of Maryland, Baltimore
    Inventor: Michael Donnenberg
  • Pathogenic Escherichia coli associated protein
    Publication number: 20060292180
    Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.
    Type: Application
    Filed: April 25, 2006
    Publication date: December 28, 2006
    Applicant: The University of British Columbia
    Inventors: B. Finlay, Brendan Kenny, Markus Stein, Michael Donnenberg, Li-Ching Lai