Patents by Inventor MIchael DZIEGELEWSKI

MIchael DZIEGELEWSKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-TrkB antibodies
    Patent number: 11866501
    Abstract: The present invention relates to novel agonistic anti-TrkB antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: January 9, 2024
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rolf Herrmann, Remko Alexander Bakker, Sebastian Bandholtz, Peter Michael Benz, Michael Dziegelewski, Lore Katharina Florin, Cynthia Hess Kenny, Sarah Kathleen Low, Holger Rosenbrock, Sanjaya Singh, Heiko Friedrich Stahl, Sathyadevi Venkataramani, Vladimir H. Voynov, Haiguang Xiao
  • MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT
    Publication number: 20230340130
    Abstract: The present invention relates to novel B7H6/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: June 20, 2023
    Publication date: October 26, 2023
    Inventors: Susanne HIPP, Paul ADAM, Michael DZIEGELEWSKI, Rajukumar GANESAN, Phillip Nicholas GORMAN, Pankaj GUPTA, Priyanka GUPTA, Marcio LASARO, Justin M. SCHEER, Vladimir H. VOYNOV
  • MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT
    Publication number: 20230295337
    Abstract: The present invention relates to novel DLL3/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: June 1, 2023
    Publication date: September 21, 2023
    Inventors: Susanne HIPP, Paul ADAM, Michael DZIEGELEWSKI, Rajkumar GANESAN, Philip Nicholas GORMAN, Pankaj GUPTA, Priyanka GUPTA, Justin SCHEER, Vladimir H. VOYNOV
  • Multi-specific binding proteins for cancer treatment
    Patent number: 11732045
    Abstract: The present invention relates to novel B7H6/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: August 22, 2023
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Susanne Hipp, Paul Adam, Michael Dziegelewski, Rajkumar Ganesan, Philip Nicholas Gorman, Pankaj Gupta, Priyanka Gupta, Marcio Lasaro, Justin M. Scheer, Vladimir H. Voynov
  • ANTI-ANGPT2 ANTIBODIES
    Publication number: 20220363743
    Abstract: The present invention relates to new anti-angiopoietin 2 (ANGPT2) neutralizing antibodies for therapeutic and diagnostic methods and composition using them.
    Type: Application
    Filed: June 17, 2022
    Publication date: November 17, 2022
    Inventors: Ryan Michael FRYER, Chao ZHENG, Michael DZIEGELEWSKI, Pankaj GUPTA
  • MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT
    Publication number: 20220251236
    Abstract: The present invention relates to novel DLL3/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: March 4, 2022
    Publication date: August 11, 2022
    Inventors: Susanne Hipp, Paul Adam, Michael Dziegelewski, Rajkumar Ganesan, Philip Nicholas Gorman, Priyanka Gupta, Justin Scheer, Vladimir H. Voynov, Pankaj GUPTA
  • Anti-ANGPT2 antibodies
    Patent number: 11396539
    Abstract: The present invention relates to new anti-angiopoietin 2 (ANGPT2) neutralizing antibodies for therapeutic and diagnostic methods and composition using them.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: July 26, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Ryan Michael Fryer, Chao Zheng, Michael Dziegelewski, Pankaj Gupta
  • Anti-BAFF antibodies
    Patent number: 11370818
    Abstract: The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: June 28, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Scott Ronald Brodeur, Keith A. Canada, Michael Dziegelewski, Philip Nicholas Gorman, Pankaj Gupta, Ashraf Khalil, John J. Miglietta, Amy Marie Nicoletti, Qi Pan, David Presky, Sanjaya Singh, Tao Wu, Haiguang Xiao
  • Multi-specific binding proteins for cancer treatment
    Patent number: 11332541
    Abstract: The present invention relates to novel DLL3/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: May 17, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Susanne Hipp, Paul Adam, Michael Dziegelewski, Rajkumar Ganesan, Philip Nicholas Gorman, Priyanka Gupta, Justin Scheer, Vladimir H. Voynov, Pankaj Gupta
  • MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT
    Publication number: 20210107983
    Abstract: The present invention relates to novel B7H6/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: October 1, 2020
    Publication date: April 15, 2021
    Inventors: Susanne HIPP, Paul ADAM, Michael DZIEGELEWSKI, Rajkumar GANESAN, Philip Nicholas GORMAN, Pankaj GUPTA, Priyanka GUPTA, Marcio LASARO, Justin M. SCHEER, Vladimir M. VOYNOV
  • ANTI-ANGPT2 ANTIBODIES
    Publication number: 20200407435
    Abstract: The present invention relates to new anti-angiopoietin 2 (ANGPT2) neutralizing antibodies for therapeutic and diagnostic methods and composition using them.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 31, 2020
    Inventors: Ryan Michael FRYER, Chao ZHENG, Michael DZIEGELEWSKI, Pankaj GUPTA, Thierry BOUYSSOU, Paul NICKLIN
  • ANTI-TRKB ANTIBODIES
    Publication number: 20200399378
    Abstract: The present invention relates to novel agonistic anti-TrkB antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 24, 2020
    Inventors: Rolf HERRMANN, Remko Alexander BAKKER, Sebastian BANDHOLTZ, Peter Michael BENZ, Michael DZIEGELEWSKI, Lore Katharina FLORIN, Cynthia Hess KENNY, Sarah Kathleen LOW, Holger ROSENBROCK, Sanjaya SINGH, Heiko Friedrich STAHL, Sathyadevi VENKATARAMANI, Vladimir H. VOYNOV, Haiguang XIAO
  • Anti-TrkB antibodies
    Patent number: 10793634
    Abstract: The present invention relates to novel agonistic anti-TrkB antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: October 6, 2020
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rolf Herrmann, Remko Alexander Bakker, Sebastian Bandholtz, Peter Michael Benz, Michael Dziegelewski, Lore Florin, Cynthia Hess Kenny, Sarah Low, Holger Rosenbrock, Sanjaya Singh, Heiko Friedrich Stahl, Sathyadevi Venkataramani, Vladimir Voynov, Haiguang Xiao
  • MULTI-SPECIFIC BINDING PROTEINS FOR CANCER TREATMENT
    Publication number: 20190375849
    Abstract: The present invention relates to novel DLL3/CD3 binding proteins. The invention also relates to nucleic acids encoding such proteins; to methods for preparing such proteins; to host cells expressing or capable of expressing such proteins; to compositions comprising such proteins; and to uses of such proteins or such compositions, in particular for therapeutic purposes in the field of cancer diseases.
    Type: Application
    Filed: June 7, 2019
    Publication date: December 12, 2019
    Inventors: Susanne Hipp, Paul Adam, Michael Dziegelewski, Rajkumar Ganesan, Nicholas Gorman, Priyanka Gupta, Justin Scheer, Vladimir H. Voynov
  • NOVEL ANTI-BAFF ANTIBODIES
    Publication number: 20190309034
    Abstract: The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: June 25, 2019
    Publication date: October 10, 2019
    Inventors: Scott Ronald BRODEUR, Keith A. CANADA, Michael DZIEGELEWSKI, Philip Nicholas GORMAN, Pankaj GUPTA, Ashraf KHALIL, John J. MIGLIETTA, Amy Marie NICOLETTI, Qi PAN, David PRESKY, Sanjaya SINGH, Tao WU, Haiguang XIAO
  • Anti-BAFF antibodies
    Patent number: 10377804
    Abstract: The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: August 13, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Scott Ronald Brodeur, Keith A. Canada, Michael Dziegelewski, Philip Nicholas Gorman, Pankaj Gupta, Ashraf Khalil, John J. Miglietta, Amy Marie Nicoletti, Qi Pan, David Presky, Sanjaya Singh, Tao Wu, Haiguang Xiao
  • ANTI-TRKB ANTIBODIES
    Publication number: 20180355046
    Abstract: The present invention relates to novel agonistic anti-TrkB antibodies and therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: June 7, 2018
    Publication date: December 13, 2018
    Inventors: Rolf Herrmann, Remko Alexander Bakker, Sebastian Bandholtz, Peter Michael Benz, Michael Dziegelewski, Lore Florin, Cynthia Hess Kenny, Sarah Low, Holger Rosenbrock, Sanjaya Singh, Heiko Friedrich Stahl, Sathyadevi Venkataramani, Vladimir Voynov, Haiguang Xiao
  • NOVEL ANTI-BAFF ANTIBODIES
    Publication number: 20180127474
    Abstract: The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: November 6, 2017
    Publication date: May 10, 2018
    Inventors: Scott Ronald BRODEUR, Keith A. CANADA, Michael DZIEGELEWSKI, Philip Nicholas GORMAN, Pankaj GUPTA, Ashraf KHALIL, John J. MIGLIETTA, Amy Marie NICOLETTI, Qi PAN, David PRESKY, Sanjaya SINGH, Tao WU, Haiguang XIAO
  • NOVEL ANTI-BAFF ANTIBODIES
    Publication number: 20150218267
    Abstract: The present invention relates to anti-BAFF antibody molecules, including novel humanized anti-BAFF antibodies, therapeutic and diagnostic methods and compositions for using the same.
    Type: Application
    Filed: January 30, 2015
    Publication date: August 6, 2015
    Inventors: Scott Ronald BRODEUR, Keith CANADA, MIchael DZIEGELEWSKI, Philip Nicholas GORMAN, Pankaj GUPTA, Ashraf KHALIL, John James MIGLIETTA, Amy Marie NICOLETTI, Qi PAN, David PRESKY, Sanjaya SINGH, Tao WU, Haiguang Xiao