Patents by Inventor Michael E. Cobb
Michael E. Cobb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5413939Abstract: A solid-phase binding assay that measures interferometrically either antibodies or binding pair antigens bound to a spinning disc on which the complementary antigen or antibody has previously been coated in an alternating pattern of immunologically active and inactive spots. The spinning disc is inserted into one arm of a Mach-Zehnder interferometer and as the disc spins the bound and unbound spots pass one after another through the two light beams causing a periodic phase shift in the light. These phase modulated light beams are then recombined at a beam-splitter converting the phase modulation into an amplitude modulation. The two recombined beams then fall on a photodetector which converts the periodically varying optical power into a periodically varying electrical current whose amplitude is proportional to the amount of bound protein on the surface of the disc and whose modulation frequency is equal to the frequency with which the spots pass through the light beam.Type: GrantFiled: June 29, 1993Date of Patent: May 9, 1995Assignee: First Medical, Inc.Inventors: Eric K. Gustafson, Jimmy D. Allen, Michael E. Cobb
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Patent number: 5300779Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: August 18, 1992Date of Patent: April 5, 1994Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5204525Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: July 19, 1991Date of Patent: April 20, 1993Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5164598Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: February 5, 1991Date of Patent: November 17, 1992Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5144139Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: July 19, 1991Date of Patent: September 1, 1992Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5140161Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastics devices is also described along with various control devices for use with the basic device.Type: GrantFiled: July 23, 1991Date of Patent: August 18, 1992Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5077017Abstract: A dilution and mixing cartridge comprising a sample application site, a mixing chamber in fluid receiving relationship to the sample application site, a diluent application site in fluid donating relationship to the mixing chamber, a first valve means selectively preventing flow from the diluent application site to the mixing chamber, and a mixture isolating chamber hydrostatically connected to the mixing chamber is provided along with a method for using this cartridge to sequentially dilute a sample with the same or different diluents.Type: GrantFiled: November 5, 1987Date of Patent: December 31, 1991Assignee: Biotrack, Inc.Inventors: Michael M. Gorin, Robert S. Hillman, Ian Gibbons, Michael E. Cobb
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Patent number: 5004923Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: January 30, 1990Date of Patent: April 2, 1991Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 4963498Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the device.Type: GrantFiled: January 15, 1988Date of Patent: October 16, 1990Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 4948961Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutiniation particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: April 5, 1988Date of Patent: August 14, 1990Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 4797283Abstract: An automatic drug tape dispensing and metering device and a roll of drug tape housed in a small portable dispenser unit. The dispenser contains a measurement device for carefully measuring the length of tape as it is dispensed from the dispenser. A counter monitors the remaining doses of drug tape remaining within the dispenser. A timer device may be provided to alert the patient that it is time for the medicament to be dispensed. As the lid of the dispenser unit is opened, the measured length of drug tape is severed from the roll by a cutter blade incorporated into the lid. The device permits a physician to accurately customize the dosage and administration of the medicament to be given a patient by adjusting the tape length released for each single dose and selecting the time intervals between dosages.Type: GrantFiled: September 23, 1987Date of Patent: January 10, 1989Assignee: Biotrack, IncorporatedInventors: Jimmy D. Allen, Michael E. Cobb, Robert S. Hillman, Dennis R. Mungall, Vladimir E. Ostoich, Gary H. Stroy
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Patent number: 4756884Abstract: Methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the device.Type: GrantFiled: July 1, 1986Date of Patent: July 12, 1988Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jim Allen, Ian Gibbons, Vladimir Ostoich, Laura J. Winfrey
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Patent number: 4712460Abstract: An automatic drug tape dispensing and metering device and a roll of drug tape housed in a small portable dispenser unit. The dispenser contains a measurement device for carefully measuring the length of tape as it is dispensed from the dispenser. A counter monitors the remaining doses of drug tape remaining within the dispenser. A timer device may be provided to alert the patient that it is time for the medicament to be dispensed. As the lid of the dispenser unit is opened, the measured length of drug tape is severed from the roll by a cutter blade incorporated into the lid. The device permits a physician to accurately customize the dosage and administration of the medicament to be givne a patient by adjusting the tape length released for each single dose and selecting the time intervals between dosages.Type: GrantFiled: November 18, 1985Date of Patent: December 15, 1987Assignee: Biotrack, Inc.Inventors: Jimmy D. Allen, Michael E. Cobb, Robert S. Hillman, Dennis R. Mungall, Vladimir E. Ostoich, Gary H. Stroy