Patents by Inventor Michael E. Le Tourneau

Michael E. Le Tourneau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dipyrazoles and their use as bronchodilators
    Patent number: 4734430
    Abstract: A group of variously methyl-substituted[1,2-c:3,4-c']dipyrazoles, cyclohepta[1,2-c:3,4-c']dipyrazoles, and cyclopenta[1,2-c:3,4-c']dipyrazoles useful as bronchodilators are described herein. The compounds are prepared by reacting a 1,3-diketone with hydrazine or methylhydrazine to give tricyclic products optionally followed by catalytic dehydrogenation and/or alkylation with a strong base and methyl iodide to give various other compounds within the scope of the invention.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: March 29, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael E. Le Tourneau, Norton P. Peet
  • Thiopyranodipyrazoles and their use as bronchodilators
    Patent number: 4734431
    Abstract: The present invention is directed to a group of compounds which are variously methylated thiopyranodipyrazoles and to the S-oxides and S-dioxides of such compounds. The compounds are useful as bronchodilators and are prepared by the reaction of appropriately 5-substituted thiopyrano[3,4-c]pyrazol-4-(1H)-one with a hydrazine.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: March 29, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael E. Le Tourneau, Norton P. Peet
  • Cycloalkane[1,2-c:4,3-c']dipyrazoles and their use as bronchodilators
    Patent number: 4734429
    Abstract: The present invention is directed to a group of methylated tetrahydro cyclohepta[1,2-c:4,3-c']dipyrazoles and benzo[1,2-c:4,3-c']dipyrazoles useful as bronchodilators. The compounds are prepared by the reaction of an appropriate hydrazine with an appropriate 1,3-diketone or with a compound that is chemically equivalent to a 1,3-diketone.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: March 29, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael E. Le Tourneau, Norton P. Peet