Patents by Inventor Michael Edward Pacold

Michael Edward Pacold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA REPAIR ENZYME INHIBITOR NANOPARTICLES AND USES THEREOF
    Publication number: 20140017165
    Abstract: This invention relates generally to the discovery of novel nanoparticles for delivery of DNA double-stranded break (DSB) repair enzyme inhibitors such as wortmannin or wortmannin analogues. In one embodiment, these nanoparticles comprise a polylactide polyglycolide (PLGA) copolymer and a polyethylene glycol (PEG). In addition methods of treatment and methods of enhancing radiation treatments are also provided.
    Type: Application
    Filed: January 11, 2012
    Publication date: January 16, 2014
    Inventors: Zhuang Wang, Michael Edward Pacold, Michael Edward Werner, Shrirang Karve