Abstract: Provided is an antibody composition comprising antibodies that specifically bind to 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol. Also provided is a method of making antibodies that specifically bind to 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol is provided. Further provided is a method of assaying for 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol is provided. Still further provided is a kit for detecting 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol.

Abstract: A system and a method are disclosed for providing recommendations for sets of security operations for improving security of documents created or executed within an online document system. A supplier entity may select sets of security operations to be performed for a request provided to a signing entity. The online document system computes an aggregate measure of security for the selected sets of security operations and compares it to a threshold measure of security. If the aggregate measure is less than the threshold measure, the online document system uses a machine-learned model to identify additional sets of security operations that when added, results in an updated aggregate measure of security greater than the threshold. The additional sets of security operations are presented to the supplier entity for inclusion within a security operation workflow in combination with the selected sets of security operations.

Abstract: A method for evaluating edge quality in an image includes receiving an image from a camera of a vehicle, detecting an edge in the image captured by the camera, fitting a polynomial curve to the edge in the image captured by the camera, executing a numerical optimizer to determine a minimum distance from each pixel in the image of the edge to the polynomial curve, determining a modulation transfer function (MTF) value using the minimum distance, determining whether the MTF value is greater than predetermined threshold, and providing an alert in response to determining that the MTF value is not greater than the predetermined threshold.

Abstract: Small optics (femtooptics) may be made with optical metasurfaces or diffractive surfaces. Baffles may be formed in the femtooptics with through-glass-via techniques or a variety of etching strategies. Femtooptics may in addition be made using wafer stacking techniques. Variations and combinations of these approaches lead to femtooptics manufacturable in vast quantities by semiconductor wafer processing techniques, also referred to as wafer level optics.

Abstract: There is provided a system and method of determining an overlay measurement between a first layer and a second layer of a specimen. The method includes acquiring a first image of a first structure on the first layer and a second image of a second structure on the second layer, obtaining one or more first regions of interest (ROIs) enclosing part of the first structure and one or more second ROIs enclosing part of the second structure, determining one or more first sets of symmetric sub-structures based on the first ROIs and one or more second sets of symmetric sub-structures based on the second ROIs, localizing a first center of symmetry (COS) based on a COS identified for each first set, and localizing a second COS based on a COS identified for each second set, and determining the overlay measurement based on the first COS and the second COS.

Abstract: A system and a method are disclosed for providing recommendations for sets of security operations for improving security of documents created or executed within an online document system. A supplier entity may select sets of security operations to be performed for a request provided to a signing entity. The online document system computes an aggregate measure of security for the selected sets of security operations and compares it to a threshold measure of security. If the aggregate measure is less than the threshold measure, the online document system uses a machine-learned model to identify additional sets of security operations that when added, results in an updated aggregate measure of security greater than the threshold. The additional sets of security operations are presented to the supplier entity for inclusion within a security operation workflow in combination with the selected sets of security operations.

Abstract: In some implementations, a method includes: obtaining first input data while presenting a computer-generated reality (CGR) environment from the perspective of a first character associated with a first time slice within predetermined content; determining whether or not the first input data satisfies first performance criteria associated with the first character for the first time slice within the predetermined content; and, in response to determining that the first input data satisfies the first performance criteria associated with the first character for the first time slice within the predetermined content, updating the CGR environment from the perspective of the first character associated with a second time slice within the predetermined content.

Abstract: Methods, devices, and systems are provided for synchronizing a source device with a sink device. In some examples, the source device plays first audio using, e.g., an electro-acoustic transducer. The source device transmits a stream of packets to the sink device to be used by the sink device for playing second audio, where the playing of the second audio is to be synchronized within a predefined tolerance with the playing of the first audio. In response to determining there is a delay in average packet arrival times of the stream of packets at the sink device, the source device adjusts the playing of the first audio to maintain synchronization with the playing of the second audio within the predefined tolerance.

Abstract: A method is provided for synchronizing a source device with a sink device. The source device transmits a stream of packets to the sink device. The source device receives feedback from the sink device indicating packet arrival times of the packets at the sink device. Based on the feedback, in some aspects, the source device determines an average time shift in the packet arrival times at the sink device, wherein the average time shift is relative to expected packet arrival times of the packets at the sink device. In some such aspects, the source device detects that the average time shift exceeds a threshold, and in response to the detecting, adjusts a streaming time of the stream of packets to synchronize, within a predefined tolerance, the source device with the sink device.

Abstract: A system and a method are disclosed for providing recommendations for sets of security operations for improving security of documents created or executed within an online document system. A supplier entity may select sets of security operations to be performed for a request provided to a signing entity. The online document system computes an aggregate measure of security for the selected sets of security operations and compares it to a threshold measure of security. If the aggregate measure is less than the threshold measure, the online document system uses a machine-learned model to identify additional sets of security operations that when added, results in an updated aggregate measure of security greater than the threshold. The additional sets of security operations are presented to the supplier entity for inclusion within a security operation workflow in combination with the selected sets of security operations.

Abstract: In some implementations, a method includes: obtaining first input data while presenting a computer-generated reality (CGR) environment from the perspective of a first character associated with a first time slice within predetermined content; determining whether or not the first input data satisfies first performance criteria associated with the first character for the first time slice within the predetermined content; and, in response to determining that the first input data satisfies the first performance criteria associated with the first character for the first time slice within the predetermined content, updating the CGR environment from the perspective of the first character associated with a second time slice within the predetermined content.

Abstract: The present invention relates to a method to produce a homogenized tobacco material for use in a heat-not-burn aerosol-generating article, comprising the steps of: selecting a first target value for a first tobacco characteristic, said first tobacco characteristic being reducing sugars and the first target value being comprised between about 8 percent and about 18 percent in dry weight basis of a total amount of tobacco present within the homogenized tobacco material; selecting a second target value of a second tobacco characteristic, wherein the second tobacco characteristic is one of total ammonia and total alkaloids; blending graded tobacco types so as to form the tobacco blend, each graded tobacco type comprising a predetermined amount of the first and second tobacco characteristics, so that the first and second target values of said first and second tobacco characteristics are obtained in said blend within a predetermined tolerance range; grinding said tobacco blend into a blended tobacco powder; form

Abstract: In some implementations, a method includes: obtaining first input data while presenting a computer-generated reality (CGR) environment from the perspective of a first character associated with a first time slice within predetermined content; determining whether or not the first input data satisfies first performance criteria associated with the first character for the first time slice within the predetermined content; and, in response to determining that the first input data satisfies the first performance criteria associated with the first character for the first time slice within the predetermined content, updating the CGR environment from the perspective of the first character associated with a second time slice within the predetermined content.

Abstract: A method is provided for synchronizing a source device with a sink device. The source device transmits a stream of packets to the sink device. The source device receives feedback from the sink device indicating packet arrival times of the packets at the sink device. Based on the feedback, in some aspects, the source device determines an average time shift in the packet arrival times at the sink device, wherein the average time shift is relative to expected packet arrival times of the packets at the sink device. In some such aspects, the source device detects that the average time shift exceeds a threshold, and in response to the detecting, adjusts a streaming time of the stream of packets to synchronize, within a predefined tolerance, the source device with the sink device.

Abstract: A method is provided for synchronizing a source device with a sink device. The source device transmits a stream of packets to the sink device. The source device receives feedback from the sink device indicating packet arrival times of the packets at the sink device. Based on the feedback, in some aspects, the source device determines an average time shift in the packet arrival times at the sink device, wherein the average time shift is relative to expected packet arrival times of the packets at the sink device. In some such aspects, the source device detects that the average time shift exceeds a threshold, and in response to the detecting, adjusts a streaming time of the stream of packets to synchronize, within a predefined tolerance, the source device with the sink device.

Abstract: A method is provided for synchronizing a source device with a sink device. The source device transmits a stream of packets to the sink device. The source device receives feedback from the sink device indicating packet arrival times of the packets at the sink device. Based on the feedback, in some aspects, the source device determines an average time shift in the packet arrival times at the sink device, wherein the average time shift is relative to expected packet arrival times of the packets at the sink device. In some such aspects, the source device detects that the average time shift exceeds a threshold, and in response to the detecting, adjusts a streaming time of the stream of packets to synchronize, within a predefined tolerance, the source device with the sink device.

Abstract: A method is provided that can be performed by an audio source for negotiating latency in an audio network. The audio source receives information regarding an audio processing latency associated with each of a set of two or more audio output devices connected to the audio network. The audio source determines, based at least on the received information, a maximum delay for outputting audio samples streamed by the audio source from the audio output devices in the set. The audio source determines, based on the maximum delay, timing for outputting the audio samples from the audio output devices in the set. The audio source then communicates the determined timing to the set of audio output devices for processing the audio samples in accordance with the timing.

Abstract: Embodiments generally relate to systems, apparatus and methods concerned with autonomous preparation of brewed beverages, such as coffee beverages. Some embodiments make use of at least one robotic arm in the brewed beverage preparation. Various embodiments use two robotic arms. Various embodiments have multiple separately controlled components with which the at least one robotic arm can interact as part of the coffee preparation process.

Abstract: A method is provided that can be performed by an audio source for negotiating latency in an audio network. The audio source receives information regarding an audio processing latency associated with each of a set of two or more audio output devices connected to the audio network. The audio source determines, based at least on the received information, a maximum delay for outputting audio samples streamed by the audio source from the audio output devices in the set. The audio source determines, based on the maximum delay, timing for outputting the audio samples from the audio output devices in the set. The audio source then communicates the determined timing to the set of audio output devices for processing the audio samples in accordance with the timing.

Abstract: A method of synchronizing playback of audio data sent over a first wireless network from an audio source to a wireless speaker package that is adapted to play the audio data. The method includes comparing a first time period over which audio data was sent over the first wireless network to a second time period over which the audio data was received by the wireless speaker package, and playing the received audio data on the wireless speaker package over a third time period that is related to the comparison of the first and second time periods.