Abstract: Devices and methods for minimally invasive suturing are disclosed. One suturing device for minimally invasive suturing includes a proximal section a distal end, and an intermediate region therebetween. The device includes a suture head assembly having a suturing needle with a pointed end and a second end. The suturing needle is capable of rotating about an axis approximately perpendicular to a longitudinal axis of the device, wherein the pointed end of the suturing needle is positioned within the suture head assembly prior to deployment of guides that are adapted and configured to guide the needle around a circular path when advanced by a drive mechanism having a needle driver for engaging and rotating the suturing needle.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: The invention provides methods and devices for repairing a ruptured ligament, meniscus, cartilage, tendon, and bone. Methods and products for delivering nucleic acids to damaged tissue are also disclosed.

Abstract: Chronic infection with retroviruses, such as HIV, induce a number of metabolic derangements. The present invention relates to a method for treating retrovirus-infected subjects with niacin compounds to reverse infection induced metabolic derangements.

Abstract: The invention provides compositions and methods for repairing intra-articular and extra-articular tissue including ligament, meniscus, cartilage, tendon, and bone. The method includes contacting the ends of an injured tissue from a patient with a composition. The repair composition includes soluble type 1 collagen, a platelet, and at least one of an extracellular protein and a neutralizing agent.

Abstract: The present invention provides siRNA methods and compositions for inhibiting HIV infection and/or replication, as well as systems for identifying effective siRNAs for inhibiting HIV and systems for studying HIV infective mechanisms. The invention also provides methods and compositions for inhibiting infection, pathogenicity and/or replication of an infectious agent; for example, by using siRNAs to inhibit host cell gene expression.

Abstract: The invention provides methods and devices for repairing a ruptured ligament, meniscus, cartilage, tendon, and bone.

Abstract: The invention provides composition and methods for repairing a ruptured anterior cruciate ligament.

Abstract: An apparatus for removing dust from a fiber sample for subsequent analysis is disclosed. A first upper cylindrical chamber containing a fiber sample has a tangential air jet and a radial air jet installed to swirl and tumble the fiber sample in a cyclonic fashion, thus liberating the dust from the sample when either a positive or a negative pressure is applied through the air jets. The liberated dust particles are then screened out through a 100 mesh screen filter and exhausted through a funnel. The device can be equipped with a second stage chamber containing a plurality of step-stage filters and a third stage plurality of microfilters to selectively screen the dust particles. A blow bottle containing an aqueous medium to absorb even the finest dust particles or gas can also be added as a fourth stage.

Abstract: An inertia actuated warning signal device for vehicles has an inertia member supported for limited reciprocating movement in a path extending along a direction of motion of an associated accelerating and decelerating vehicle, and for rotating movement about the path of reciprocating movement simultaneously with movement along the latter mentioned path.