Patents by Inventor Michael FIANDALO

Michael FIANDALO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF CATALYTIC SITE COMMON TO MULTIPLE 3 ALPHA-OXIDOREDUCTASES FOR TREATMENT OF PROSTATE CANCER
    Publication number: 20210252115
    Abstract: A method of inhibiting activity or expression of one or more 3?-oxidoreductase enzymes that share a common catalytic site and convert androstanediol to DHT. The method comprises introducing one or more agents into cells that comprise the one or more 3?-oxidoreductase enzymes, wherein said one or more agents: i) inhibit function of one or more of said enzymes; ii) inhibit translation of mRNA encoding said enzymes; iii) disrupt or delete genes encoding said enzymes; or a combination thereof.
    Type: Application
    Filed: April 23, 2021
    Publication date: August 19, 2021
    Inventors: James L. Mohler, Michael Fiandalo, David Watt, Elizabeth Wilson
  • INHIBITION OF CATALYTIC SITE COMMON TO MULTIPLE 3 ALPHA-OXIDOREDUCTASES FOR TREATMENT OF PROSTATE CANCER
    Publication number: 20200179408
    Abstract: Methods and compositions which are directed against catalytic site common to multiple 3 alpha-oxidoreductases. The compositions can be used for the treatment of prostate cancer.
    Type: Application
    Filed: March 27, 2017
    Publication date: June 11, 2020
    Inventors: James L. MOHLER, Michael FIANDALO, David WATT, Elizabeth WILSON