Patents by Inventor Michael Franti

Michael Franti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen delivery platforms
    Patent number: 11639370
    Abstract: The invention relates to platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using such platforms permits the generation of broad and potent immune responses useful for vaccine development.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: May 2, 2023
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Michael Franti, Anders Lilja, Rebecca Loomis, Peter W. Mason
  • ANTIGEN DELIVERY PLATFORMS
    Publication number: 20220213149
    Abstract: This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
    Type: Application
    Filed: March 16, 2022
    Publication date: July 7, 2022
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Michael FRANTI, Anders LILJA, Rebecca LOOMIS, Peter W. MASON
  • ANTIGEN DELIVERY PLATFORMS
    Publication number: 20220119455
    Abstract: This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
    Type: Application
    Filed: June 28, 2021
    Publication date: April 21, 2022
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Michael FRANTI, Anders LILJA, Rebecca LOOMIS, Peter W. MASON
  • Antigen delivery platforms
    Patent number: 11078237
    Abstract: This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: August 3, 2021
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Michael Franti, Anders Lilja, Rebecca Loomis, Peter W. Mason
  • Reverse genetics systems
    Patent number: 10610584
    Abstract: The invention provides various reverse genetics systems for producing segmented RNA viruses, wherein the systems do not require bacteria for propagation of all of their expression constructs.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: April 7, 2020
    Assignee: Seqirus UK Limited
    Inventors: Philip Dormitzer, Michael Franti, Peter Mason
  • REVERSE GENETICS USING NON-ENDOGENOUS POL I PROMOTERS
    Publication number: 20190284575
    Abstract: Expression of a transgene is driven in a host cell using a pol I promoter which is not endogenous to an organism from the same taxonomic order from which the host cell is derived.
    Type: Application
    Filed: January 30, 2019
    Publication date: September 19, 2019
    Inventors: Philip Dormitzer, Michael Franti, Pirada Suphaphiphat, Peter Mason, Bjoern Keiner, Stefania Crotta
  • ANTIGEN DELIVERY PLATFORMS
    Publication number: 20190144507
    Abstract: This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
    Type: Application
    Filed: August 28, 2018
    Publication date: May 16, 2019
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: Michael Franti, Anders Lilja, Rebecca Loomis, Peter Mason
  • REVERSE GENETICS SYSTEMS
    Publication number: 20180236058
    Abstract: The invention provides various reverse genetics systems for producing segmented RNA viruses, wherein the systems do not require bacteria for propagation of all of their expression constructs.
    Type: Application
    Filed: October 16, 2017
    Publication date: August 23, 2018
    Inventors: Philip DORMITZER, Michael Franti, Peter Mason
  • Reverse genetics systems
    Patent number: 9821052
    Abstract: The invention provides various reverse genetics systems for producing segmented RNA viruses, wherein the systems do not require bacteria for propagation of all of their expression constructs.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: November 21, 2017
    Assignee: Seqirus UK Limited
    Inventors: Philip Dormitzer, Michael Franti, Peter Mason
  • Influenza virus reassortment method
    Patent number: 9574181
    Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: February 21, 2017
    Assignee: Seqirus UK Limited
    Inventors: Heidi Trusheim, Peter Mason, Michael Franti, Björn Keiner, Melissa Sackal, Juerg Hunziker, David Morrissey, François Jean-Charles Natt
  • REVERSE GENETICS USING NON-ENDOGENOUS POL I PROMOTERS
    Publication number: 20160024525
    Abstract: Expression of a transgene is driven in a host cell using a pol I promoter which is not endogenous to an organism from the same taxonomic order from which the host cell is derived.
    Type: Application
    Filed: May 7, 2015
    Publication date: January 28, 2016
    Applicant: NOVARTIS AG
    Inventors: Philip DORMITZER, Michael FRANTI, Pirada SUPHAPHIPHAT, Peter MASON, Bjoern KEINER, Stefania CROTTA
  • Reverse genetics using non-endogenous pol I promoters
    Patent number: 9072702
    Abstract: Expression of a transgene is driven in a host cell using a pol I promoter which is not endogenous to an organism from the same taxonomic order from which the host cell is derived.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: July 7, 2015
    Assignee: Novartis AG
    Inventors: Philip Dormitzer, Michael Franti, Peter Mason, Pirada Suphaphiphat, Bjoern Keiner, Stefania Crotta
  • REVERSE GENETICS METHODS FOR VIRUS RESCUE
    Publication number: 20150166966
    Abstract: A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
    Type: Application
    Filed: October 1, 2014
    Publication date: June 18, 2015
    Inventors: Philip Dormitzer, Björn Keiner, Pirada Suphaphiphat, Michael Franti, Peter Mason, Jennifer Uhlendorff, Mikhail Matrosovich
  • INFLUENZA VIRUS REASSORTMENT METHOD
    Publication number: 20150118746
    Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.
    Type: Application
    Filed: October 24, 2014
    Publication date: April 30, 2015
    Inventors: Heidi TRUSHEIM, Peter MASON, Michael FRANTI, Björn KEINER, Melissa SACKAL, Juerg HUNZIKER, David MORRISSEY, François Jean-Charles NATT
  • Influenza virus reassortment
    Patent number: 8945904
    Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: February 3, 2015
    Assignee: Novartis AG
    Inventors: Heidi Trusheim, Peter Mason, Michael Franti, Bjoern Keiner, Melissa Sackal, Juerg Hunziker, Francois Natt, David Morrissey
  • Reverse genetics methods for virus rescue
    Patent number: 8883481
    Abstract: A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: November 11, 2014
    Assignee: Novartis AG
    Inventors: Philip Dormitzer, Björn Keiner, Pirada Suphaphiphat, Michael Franti, Peter Mason, Jennifer Uhlendorff, Mikhail Matrosovich
  • ANTIGEN DELIVERY PLATFORMS
    Publication number: 20140030292
    Abstract: This disclosure provides platforms for delivery of herpes virus proteins to cells, particularly proteins that form complexes in vivo. In some embodiments these proteins and the complexes they form elicit potent neutralizing antibodies. Thus, presentation of herpes virus proteins using the disclosed platforms permits the generation of broad and potent immune responses useful for vaccine development.
    Type: Application
    Filed: October 11, 2011
    Publication date: January 30, 2014
    Applicant: Novartis AG
    Inventors: Michael Franti, Anders Lilja, Rebecca Loomis, Peter Mason
  • INFLUENZA VIRUS REASSORTMENT
    Publication number: 20130216573
    Abstract: Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.
    Type: Application
    Filed: May 20, 2011
    Publication date: August 22, 2013
    Applicant: NOVARTIS AG
    Inventors: Heidi Trusheim, Peter Mason, Michael Franti, Bjoern Keiner, Melissa Sackal, Juerg Hunziker, Francois Natt, David Morrissey
  • REVERSE GENETICS METHODS FOR VIRUS RESCUE
    Publication number: 20130034582
    Abstract: A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
    Type: Application
    Filed: October 20, 2010
    Publication date: February 7, 2013
    Applicant: NOVARTIS AG
    Inventors: Philip Dormitzer, Björn Keiner, Pirada Suphaphiphat, Michael Franti, Peter Mason, Jennifer Uhlendorff, Mikhail Matrosovich
  • REVERSE GENETICS SYSTEMS
    Publication number: 20120270321
    Abstract: The invention provides various reverse genetics systems for producing segmented RNA viruses, wherein the systems do not require bacteria for propagation of all of their expression constructs.
    Type: Application
    Filed: July 30, 2010
    Publication date: October 25, 2012
    Applicant: NOVARTIS AG
    Inventors: Philip Dormitzer, Michael Franti, Peter Mason