Patents by Inventor Michael G. Garwood
Michael G. Garwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11241296Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: November 30, 2017Date of Patent: February 8, 2022Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 10564241Abstract: A method for generating a magnetic resonance image includes applying a radio frequency (RF) pulse to a specimen. The method includes modulating a spatially varying magnetic field to impart an angular velocity to a trajectory of a region of resonance relative to the specimen. The method includes acquiring data corresponding to the region of resonance and reconstructing a representation of the specimen based on the data.Type: GrantFiled: January 17, 2013Date of Patent: February 18, 2020Assignee: Regents of the University of MinnesotaInventors: Angela Lynn Styczynski Snyder, Curtis A. Corum, Djaudat S. Idiyatullin, Steen Moeller, Michael G. Garwood
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Patent number: 10537265Abstract: A system includes a data receiver, a sinogram generator, a processor, a filter module, and an output module. The data receiver is configured to receive radial ordered magnetic resonance data. The sinogram generator is configured to generate a first sinogram corresponding to a view angle as a function of a readout direction for the magnetic resonance data. The processor is configured to generate an oscillogram having an angular frequency axis. The oscillogram corresponds to a Fourier transform of the first sinogram. The filter module is configured to selectively filter a peak in a projection formed along a selected axis of the oscillogram, the peak being related to an interference signal such as an RF interference. The selected axis is orthogonal to the angular frequency axis. The output module is configured to form a second sinogram corresponding to a transform of the filtered projection.Type: GrantFiled: March 31, 2011Date of Patent: January 21, 2020Assignee: Regents of the University of MinnesotaInventors: Curtis A. Corum, Djaudat S. Idiyatullin, Steen Moeller, Michael G. Garwood
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Publication number: 20180085184Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: November 30, 2017Publication date: March 29, 2018Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 9903928Abstract: A method for generating a magnetic resonance image includes configuring a magnetic field to correspond to a trajectory within a region of interest. The method includes applying RF excitation to spatially control a region of magnetic resonance corresponding to the trajectory. The method includes modulating the magnetic field coincident with the spatially controlled region of magnetic resonance. The method includes acquiring data corresponding to the region of magnetic resonance and generating an image based on the data.Type: GrantFiled: February 6, 2014Date of Patent: February 27, 2018Assignee: Regents of the University of MinnesotaInventors: Angela Lynn Styczynski Snyder, Carl J. Snyder, Michael G. Garwood, J. Thomas Vaughan, Jr.
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Patent number: 9880243Abstract: A method includes applying a pulse train to a spin system in a scanner. The pulse train has a plurality of discontinuities in a time domain. The method includes receiving a response from the spin system. The response corresponds to a gated signal. The method includes accessing a correction factor corresponding to the scanner. The method includes calculating a correction to the response based on the correction factor. The method includes generating an output based on the correction.Type: GrantFiled: June 19, 2012Date of Patent: January 30, 2018Assignee: Regents of the University of MinnesotaInventors: Curtis A. Corum, Steen Moeller, Djaudat S. Idiyatullin, Ryan Chamberlain, Michael G. Garwood
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Patent number: 9861450Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: December 11, 2015Date of Patent: January 9, 2018Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 9841480Abstract: Positive contrast localization of magnetic (e.g. superparamagnetic) particles in vivo or in vitro by means of SWIFT-MRI using the imaginary component of MR image data in combination with an anatomic reference image derived from the real or magnitude component.Type: GrantFiled: April 1, 2010Date of Patent: December 12, 2017Assignee: Regents of the University of MinnesotaInventors: Curtis A. Corum, Djaudat S. Idiyatullin, Steen Moeller, Michael G. Garwood
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Patent number: 9714997Abstract: Positive contrast localization of magnetic (e.g. superparamagnetic) particles in vivo or in vitro by means of SWIFT-MRI using the imaginary component of MR image data in combination with an anatomic reference image derived from the real or magnitude component.Type: GrantFiled: April 1, 2010Date of Patent: July 25, 2017Assignee: Regents of the University of MinnesotaInventors: Curtis A. Corum, Djaudat S. Idiyatullin, Steen Moeller, Michael G. Garwood
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Patent number: 9341691Abstract: A method for magnetic resonance imaging includes providing a radio frequency excitation pulse to a specimen. The pulse has a duration. The method includes, concurrent with providing the radio frequency excitation pulse, applying a first gradient having a first polarity. The method includes applying a readout gradient at a time after the duration. The readout gradient has inverse polarity relative to the first polarity. The method includes, concurrent with applying the readout gradient, acquiring magnetic resonance data from the specimen. The method includes generating an image based on the magnetic resonance data.Type: GrantFiled: November 11, 2009Date of Patent: May 17, 2016Assignee: Regents of the University of MinnesotaInventors: Jang-Yeon Park, Steen Moeller, Ryan Chamberlain, Michael G. Garwood
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Patent number: 9341692Abstract: A method includes acquiring a signal intensity from a spin system after applying the radio frequency preparation pulses prior to the imaging readout or spectroscopic localization, and acquiring signal intensity starting with magnetization initially rotated to a certain angle by applying an initial pulse before the preparation scheme, and processing the data to generate an image or spectra corresponding to the spin system. The imaging or spectroscopy sequence is configured to provide data based on magnetization transfer or an off-resonance effect.Type: GrantFiled: April 14, 2011Date of Patent: May 17, 2016Assignee: Regents of the University of MinnesotaInventors: Silvia Mangia, Shalom Michaeli, Michael G. Garwood
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Patent number: 9320452Abstract: Amyloid plaque in the brain of a subject is imaged in an MRI system with or without the use of a contrast agent. Contrast is achieved using a spin-echo pulse sequence that is both respiratory gated and cardiac gated to reduce motion artifacts at the very high image resolution required to see plaque. A preparatory pulse sequence is used to insure longitudinal magnetization remains constant for all the acquired views even if the effective TR changes during the scan due to irregular breathing.Type: GrantFiled: June 28, 2005Date of Patent: April 26, 2016Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Michael G. Garwood, Clifford R. Jack, Jr., Joseph F Poduslo, Thomas M. Wengenack
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Publication number: 20160100910Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: December 11, 2015Publication date: April 14, 2016Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 9241773Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: March 2, 2015Date of Patent: January 26, 2016Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 9222999Abstract: A system includes a driving module, a processor, and a readout module. The driving module is configured to apply a perturbation to a sample. The processor is configured to define a plurality of different rotating frames relative to the perturbation, wherein each frame has a corresponding fictitious field. The readout module is coupled to the processor and is configured to generate an output based on relaxation of the sample as a function of the perturbation.Type: GrantFiled: April 9, 2012Date of Patent: December 29, 2015Assignee: Regents of the University of MinnesotaInventors: Shalom Michaeli, Silvia Mangia, Dennis J. Sorce, Michael G. Garwood, Timo Liimatainen
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Publication number: 20150173848Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: March 2, 2015Publication date: June 25, 2015Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 8966735Abstract: An implantable tissue marker incorporates a contrast agent scaled within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: September 10, 2013Date of Patent: March 3, 2015Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 8933698Abstract: A magnetic resonance image is produced by shifting a gap during acquisition of spin data for a specimen. The spin data is generated by a gapped excitation sequence.Type: GrantFiled: August 7, 2013Date of Patent: January 13, 2015Assignee: Regents of the University of MinnesotaInventors: Curtis A. Corum, Djaudat S. Idiyatullin, Steen Moeller, Michael G. Garwood
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Publication number: 20140218028Abstract: A method for generating a magnetic resonance image includes configuring a magnetic field to correspond to a trajectory within a region of interest. The method includes applying RF excitation to spatially control a region of magnetic resonance corresponding to the trajectory. The method includes modulating the magnetic field coincident with the spatially controlled region of magnetic resonance. The method includes acquiring data corresponding to the region of magnetic resonance and generating an image based on the data.Type: ApplicationFiled: February 6, 2014Publication date: August 7, 2014Applicant: Regents of the University of MinnesotaInventors: Angela Lynn Styczynski Snyder, Carl J. Snyder, Michael G. Garwood, J. Thomas Vaughan, JR.
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Patent number: 8798340Abstract: A method includes receiving k-space data corresponding to magnetic resonance data for a subject and selecting a template for analysis. In addition, the method includes generating an image using the k-space data and using the template.Type: GrantFiled: November 9, 2010Date of Patent: August 5, 2014Assignee: Regents of the University of MinnesotaInventors: Curtis A. Corum, Michael G. Garwood, Steen Moeller, Djaudat S. Idiyatullin, Ryan Chamberlain