Patents by Inventor Michael G. Natchus

Michael G. Natchus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N4-hydroxycytidine and derivatives and anti-viral uses related thereto
    Patent number: 11903959
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: February 20, 2024
    Assignee: Emory University
    Inventors: George R. Painter, Gregory R. Bluemling, Michael G. Natchus, David Guthrie
  • PROGESTERONE PHOSPHATE ANALOGS AND USES RELATED THERETO
    Publication number: 20230357309
    Abstract: This disclosure relates to progesterone phosphate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: June 20, 2023
    Publication date: November 9, 2023
    Inventors: DAVID BRIAN GUTHRIE, MARK ANDREW LOOKWOOD, MICHAEL G. NATCHUS, DENNIS C. LIOTTA, DONALD G. STEIN, IQBAL SAYEED
  • Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction
    Patent number: 11779583
    Abstract: The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: October 10, 2023
    Assignee: EMORY UNIVERSITY
    Inventors: Michael G. Natchus, Richard Arrendale, Dennis C. Liotta, Ketan Desai, Hyunsuk Shim
  • N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto
    Publication number: 20230293566
    Abstract: This disclosure related to N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment and prophylaxis of viral infections.
    Type: Application
    Filed: March 15, 2023
    Publication date: September 21, 2023
    Inventors: George R. Painter, David Guthrie, Gregory R. Bluemling, Michael G. Natchus
  • Progesterone phosphate analogs and uses related thereto
    Patent number: 11725025
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: August 15, 2023
    Assignee: Emory University
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • N4-hydroxycytidine and derivatives and anti-viral uses related thereto
    Patent number: 11628181
    Abstract: This disclosure relates to N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment and prophylaxis of viral infections.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: April 18, 2023
    Assignee: Emory University
    Inventors: George R. Painter, David Guthrie, Gregory R. Bluemling, Michael G. Natchus
  • PROGESTERONE ANALOGS AND USES RELATED THERETO
    Publication number: 20220235092
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: February 4, 2022
    Publication date: July 28, 2022
    Applicant: EMORY UNIVERSITY
    Inventors: David B. Guthrie, Mark A. Lockwood, Dennis C. Liotta, Michael G. Natchus, Donald G. Stein, Iqbal Sayeed
  • N4-hydroxycytidine and derivatives and anti-viral uses related thereto
    Patent number: 11331331
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: May 17, 2022
    Assignee: Emory University
    Inventors: George R. Painter, Gregory R. Bluemling, Michael G. Natchus, David Guthrie
  • Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction
    Patent number: 11285151
    Abstract: The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: March 29, 2022
    Assignee: EMORY UNIVERSITY
    Inventors: Michael G. Natchus, Richard Arrendale, Dennis Liotta, Ketan Desai, Hyunsuk Shim
  • Progesterone analogs and uses related thereto
    Patent number: 11274118
    Abstract: This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: March 15, 2022
    Assignee: EMORY UNIVERSITY
    Inventors: David B Guthrie, Mark A Lockwood, Dennis C. Liotta, Michael G Natchus, Donald G. Stein, Iqbal Sayeed
  • Tricyclic Amino Containing Compounds for Treatment or Prevention of Symptoms Associated with Endocrine Dysfunction
    Publication number: 20220040174
    Abstract: The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
    Type: Application
    Filed: August 23, 2019
    Publication date: February 10, 2022
    Inventors: Michael G. Natchus, Richard Arrendale, Dennis Liotta, Ketan Desai, Hyunsuk Shim
  • N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO
    Publication number: 20220016153
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
    Type: Application
    Filed: September 2, 2021
    Publication date: January 20, 2022
    Inventors: George R. PAINTER, Gregory R. Bluemling, Michael G. Natchus, David Guthrie
  • TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION
    Publication number: 20210401836
    Abstract: The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
    Type: Application
    Filed: August 31, 2021
    Publication date: December 30, 2021
    Applicant: EMORY UNIVERSITY
    Inventors: Michael G. Natchus, Richard Arrendale, Dennis C. Liotta, Ketan Desai, Hyunsuk Shim
  • PROGESTERONE PHOSPHATE ANALOGS AND USES RELATED THERETO
    Publication number: 20210395294
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 23, 2021
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • N4-hydroxycytidine and derivatives and anti-viral uses related thereto
    Patent number: 11197882
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: December 14, 2021
    Assignee: Emory University
    Inventors: George R. Painter, Gregory R. Bluemling, Michael G. Natchus, David Guthrie
  • N4-hydroxycytidine and derivatives and anti-viral uses related thereto
    Patent number: 11147826
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: October 19, 2021
    Assignee: Emory University
    Inventors: George R. Painter, Gregory R. Bluemling, Michael G. Natchus, David Guthrie
  • Progesterone phosphate analogs and uses related thereto
    Patent number: 11053276
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: July 6, 2021
    Assignee: EMORY UNIVERSITY
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed
  • N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto
    Publication number: 20210060050
    Abstract: This disclosure relates to N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment and prophylaxis of viral infections.
    Type: Application
    Filed: July 6, 2020
    Publication date: March 4, 2021
    Inventors: George R. Painter, David Guthrie, Gregory R. Bluemling, Michael G. Natchus
  • N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO
    Publication number: 20200276219
    Abstract: This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.
    Type: Application
    Filed: December 7, 2018
    Publication date: September 3, 2020
    Inventors: George R. PAINTER, Gregory R. BLUEMLING, Michael G. NATCHUS, David GUTHRIE
  • PROGESTERONE PHOSPHATE ANALOGS AND USES RELATED THERETO
    Publication number: 20200255470
    Abstract: This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.
    Type: Application
    Filed: October 11, 2019
    Publication date: August 13, 2020
    Inventors: David Brian Guthrie, Mark Andrew Lockwood, Michael G. Natchus, Dennis C. Liotta, Donald G. Stein, Iqbal Sayeed