Patents by Inventor Michael H. Kogut

Michael H. Kogut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immune lymphokine-mediated control of Salmonellosis in swine
    Patent number: 6221348
    Abstract: A method and composition for treating swine to increase their resistance to pathogenic microorganisms are disclosed. Microbial infections may be prevented or reduced in swine populations by administration of immune lymphokines which have been produced by the splenic T cells of immunized swine. The process and compositions are particularly useful for the control of Salmonella in swine.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: April 24, 2001
    Assignees: The United States of America as represented by the Secretary of Agriculture, The Texas A&M University System
    Inventors: Michael H. Kogut, Kenneth J. Genovese, Larry H. Stanker
  • Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes to produce immortalized cells
    Patent number: 5891443
    Abstract: Immortal avian T lymphocyte cell lines which produce and secrete immune lymphokines are disclosed. These cell lines may be produced from T cells recovered from fowl which have been hyperimmunized in vivo. The activated T cells are first exposed in vitro to a mitogen effective for secondary stimulation thereof, and then virally transformed to produce an immortal cell line. When cultured in vitro, the cell lines produce and secrete immune lymphokines which may be administered to fowl to increase their resistance to infections.
    Type: Grant
    Filed: September 15, 1997
    Date of Patent: April 6, 1999
    Assignees: The United States of America as represented by the Secretary of Agriculture, The Texas & M University System College
    Inventors: Michael H. Kogut, John R. DeLoach, Larry H. Stanker, Rita B. Moyes, Billy M. Hargis
  • Method of treating birds
    Patent number: 5698193
    Abstract: A method of combatting microbial infections, including Escherichia coli and Salmonella infections, in immature birds by in ovo administration of an immune lymphokine (ILK) containing preparation in an amount effective to combat microbial infections in immature birds. A method of combatting microbial infections in immature birds by upregulating the production of endogenous Interleukin-8 (IL-8) in the bird. A method of combatting microbial infections in immature birds by in ovo administration of immune lymphokine (ILK).
    Type: Grant
    Filed: December 27, 1994
    Date of Patent: December 16, 1997
    Assignees: The United States of America as represented by the Department of Agriculture, The Texas A&M University System
    Inventors: Michael H. Kogut, John R. DeLoach, Billy M. Hargis, Edward D. McGruder
  • Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes and method to produce immortalized cells
    Patent number: 5691200
    Abstract: Immortal avian T lymphocyte cell lines which produce and secrete immune lymphokines are disclosed. These cell lines may be produced from T cells recovered from fowl which have been hyperimmunized in vivo. The activated T cells are first exposed in vitro to a mitogen effective for secondary stimulation thereof, and then virally transformed to produce an immortal cell line. When cultured in vitro, the cell lines produce and secrete immune lymphokines which may be administered to fowl to increase their resistance to infections.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: November 25, 1997
    Assignees: The United States of America as represented by the Secretary of Agriculture, The Texas A&M University System
    Inventors: Michael H. Kogut, John R. DeLoach, Larry H. Stanker, Rita B. Moyes, Billy M. Hargis