Patents by Inventor Michael H. Luethy

Michael H. Luethy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced zein reduction in transgenic corn seed
    Patent number: 10772276
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: September 15, 2020
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • ENHANCED ZEIN REDUCTION IN TRANSGENIC CORN SEED
    Publication number: 20180263205
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Application
    Filed: March 9, 2018
    Publication date: September 20, 2018
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Recombinant DNA for gene suppression
    Patent number: 9976139
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: May 22, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • Enhanced zein reduction in transgenic corn seed
    Patent number: 9913487
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: March 13, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • ENHANCED ZEIN REDUCTION IN TRANSGENIC CORN SEED
    Publication number: 20180007856
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Application
    Filed: June 10, 2013
    Publication date: January 11, 2018
    Applicant: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Enhanced zein reduction in transgenic corn seed
    Patent number: 9119408
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: September 1, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • RECOMBINANT DNA FOR GENE SUPPRESSION
    Publication number: 20150191728
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Application
    Filed: March 20, 2015
    Publication date: July 9, 2015
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • Recombinant DNA for gene suppression
    Patent number: 9006414
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: April 14, 2015
    Assignee: Monsanto Technology LLC
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • ENHANCED ZEIN REDUCTION IN TRANSGENIC CORN SEED
    Publication number: 20140173778
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Application
    Filed: June 10, 2013
    Publication date: June 19, 2014
    Applicant: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • Enhanced zein reduction in transgenic corn seed
    Patent number: 8461418
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct that comprises in 5? to 3? order a promoter element operably linked to more than one anti-sense-oriented DNA element and one or more complementary DNA elements.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: June 11, 2013
    Assignee: Monsanto Technology LLC
    Inventors: Michael H. Luethy, Thomas M. Malvar, Shihshieh Huang
  • GENE SEQUENCES AND USES THEREOF IN PLANTS
    Publication number: 20130074202
    Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
    Type: Application
    Filed: May 14, 2012
    Publication date: March 21, 2013
    Applicant: Monsanto Technology LLC
    Inventors: Thomas Adams, Ameeta K. Agarwa, Jeffrey Ahrens, James A. Ball, Amarjit Basra, Erin Bell, Terry L. Bradshaw, Paul S. Chomet, James H. Crowley, Jill Deikman, Molian Deng, Meghan Donnarummo, Kimberly Faye Zobrist Duff, Stephen Duff, Michael D. Edgerton, Banu Gopalan, Xiaoping He, Mackenzie Heal, Brendan S. Hinchey, Shihshieh Huang, Richard G. Johnson, Vincent Jung, Keith Kretzmer, Lucille B. Laccetti, Chao Qiang Lai, Garrett J. Lee, Michael H. Luethy, Timothy J. Leland, Jingdong Liu, Bin Lu, Adrian A. Lund, Linda L. Madson, Kathleen P. Malloy, Marcus Paul McNabnay, Manchikanti Padmavati, Thomas Ruff, William Start, Daniel Tennessen, Carl P. Urwin, Gabriela Vaduva, K. R. Vidya, Steven Thomas Voss, Christine Voyles, Zhango Xin, Nanfei Xu, Qingzhang Xu, Qiang Zhang, Yajuan Zhao, Li Zhou
  • GENE SEQUENCES AND USES THEREOF IN PLANTS
    Publication number: 20110258734
    Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
    Type: Application
    Filed: March 11, 2011
    Publication date: October 20, 2011
    Applicant: Monsanto Technology LLC
    Inventors: Thomas Adams, Ameeta K. Agarwa, Jeffrey Ahrens, James A. Ball, Amarjit Basra, Erin Bell, Terry L. Bradshaw, Paul S. Chomet, James H. Crowley, Jill Deikman, Molian Deng, Meghan Donnarummo, Kimberly Faye Zobrist Duff, Stephen Duff, Michael D. Edgerton, Banu Gopalan, Xiaoping He, Mackenzie Heal, Brendan S. Hinchey, Shihshieh Huang, Richard G. Johnson, Vincent Jung, Keith Kretzmer, Lucille B. Laccetti, Chao Qiang Lai, Garrett J. Lee, Michael H. Luethy, Timothy J. Leland, Jingdong Liu, Bin Lu, Adrian A. Lund, Linda L. Madson, Kathleen P. Malloy, Marcus Paul McNabnay, Manchikanti Padmavati, Thomas Ruff, William Start, Daniel Tennessen, Carl P. Urwin, Gabriela Vaduva, K.R. Vidya, Steven Thomas Voss, Christine Voyles, Zhango Xin, Nanfei Xu, Qingzhang Xu, Qiang Zhang, Yajuan Zhao, Li Zhou
  • RECOMBINANT DNA FOR GENE SUPPRESSION
    Publication number: 20110126321
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Application
    Filed: December 20, 2010
    Publication date: May 26, 2011
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • TRANSGENIC PLANT SEED WITH INCREASED LYSINE
    Publication number: 20110113514
    Abstract: Disclosed herein are transgenic plants having a novel exogenous DNA construct that expresses a dihydrodipicolinic acid synthase and a gene suppression molecule for lysine ketoglutarate reductase, the activity of which results in increased lysine in a plant seed.
    Type: Application
    Filed: October 21, 2010
    Publication date: May 12, 2011
    Inventors: Thomas M. Malvar, Shihshieh Huang, Michael H. Luethy
  • Recombinant DNA Constructs and Methods for Controlling Gene Expression
    Publication number: 20110035838
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Application
    Filed: July 8, 2010
    Publication date: February 10, 2011
    Inventors: Linda Lutfiyya, Liang Guo, Philip W. Miller, Michael H. Luethy, Sara E. Heisel, Yuanji Zhang, Edwards Allen, Larry A. Gilbertson, David K. Kovalic, James K. Roberts, Shihshieh Huang, Alessandra Frizzi, Nancy Houmard, Thomas Malvar
  • Recombinant DNA for gene suppression
    Patent number: 7855323
    Abstract: Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5? to 3? order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: December 21, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Shihshieh Huang, Thomas M. Malvar, Michael H. Luethy
  • Methods and compositions for expression of transgenes in plants
    Patent number: 7803928
    Abstract: Methods and compositions for the expression of transgenes in monocot plants including maize are disclosed. In the invention, gene silencing is avoided by use of monocot-homeologous sequences from plants of the genus Coix for transformation. Included in these transgene sequences are Coix promoters, enhancers, coding sequences and terminators. Suitable alternatives to maize-derived transgenes are desirable for expression in maize in that homology-based gene silencing can limit or effectively eliminate transgene expression.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: September 28, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Alan L. Kriz, Michael H. Luethy, Dale A. Voyles
  • Methods and compositions for expression of transgenes in plants
    Patent number: 7803927
    Abstract: Methods and compositions for the expression of transgenes in monocot plants including maize are disclosed. In the invention, gene silencing is avoided by use of monocot-homeologous sequences from plants of the genus Coix for transformation. Included in these transgene sequences are Coix promoters, enhancers, coding sequences and terminators. Suitable alternatives to maize-derived transgenes are desirable for expression in maize in that homology-based gene silencing can limit or effectively eliminate transgene expression.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: September 28, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Alan L. Kriz, Michael H. Luethy, Dale A. Voyles
  • Recombinant DNA Constructs and Methods for Controlling Gene Expression
    Publication number: 20100223694
    Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
    Type: Application
    Filed: March 18, 2010
    Publication date: September 2, 2010
    Inventors: Linda Lutfiyya, Liang Guo, Philip W. Miller, Michael H. Luethy, Sara E. Heisel, Yanji Zhang, Edwards Allen, Larry A. Gilbertson, David K. Kovalic, James K. Roberts, Shihshieh Huang, Alessandra Frizzi, Nancy Houmard, Thomas Malvar
  • Methods and compositions for expression of transgenes in plants
    Patent number: 7741538
    Abstract: Methods and compositions for the expression of transgenes in monocot plants including maize are disclosed. In the invention, gene silencing is avoided by use of monocot-homeologous sequences from plants of the genus Coix for transformation. Included in these transgene sequences are Coix promoters, enhancers, coding sequences and terminators. Suitable alternatives to maize-derived transgenes are desirable for expression in maize in that homology-based gene silencing can limit or effectively eliminate transgene expression.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: June 22, 2010
    Assignee: Dekalb Genetics Corporation
    Inventors: Alan L. Kriz, Michael H. Luethy, Dale A. Voyles