Abstract: Vehicle chassis with interchangeable performance packages and related methods. are disclosed herein. An example vehicle chassis disclosed herein includes a frame including a first chassis portion including a cavity, a battery platform coupled to first chassis portion, and a first subframe couplable within the cavity, the first subframe including a first motor and a first suspension assembly, and a second subframe couplable within the cavity, the second subframe including a second motor and a second suspension assembly, the second motor having a greater power than the first motor, the second suspension assembly having a greater stiffness than the first suspension assembly.

Abstract: A rubber composition comprising 50 phr to 100 phr of a styrene butadiene rubber; 0 phr to 50 phr of at least one diene based rubber; 95 phr to 200 phr of filler comprising i) 50 phr to 100 phr of silica, ii) 40 phr to 70 phr of carbon black and iii) 5 phr to 30 phr of an inorganic metal hydroxide; 40 phr to 80 phr of plasticizer comprising a hydrocarbon resin having a softening point within a range of 80° C. and 130° C.

Abstract: Using a pressure sensor of a mobile device to improve the accuracy of determined contexts. Particular embodiments described herein include machines that determine a context of a mobile device, and determine if the determined context is accurate using multiple measurements of pressure from a pressure sensor of the mobile device.

Abstract: A lock core includes a shell, a plug within and rotatable relative to the shell between a first position and a second position about a longitudinal axis of the plug, and a lock. The lock has a first locked position preventing rotation of the plug relative to the shell, an unlocked position allowing rotation of the plug relative to the shell and a second locked position different from the first locked position preventing rotation of the plug relative to the shell.

Abstract: Extending the spatial coverage of a reference pressure network. Particular embodiments described herein include machines that initially determine that an estimated position of a mobile device resides outside a coverage area of a network of reference pressure sensors. Reference-level pressures are determined using measurements of pressure from the network of reference pressure sensors. A time interval and a plurality of wind speeds and corresponding wind directions are used to determine an adjusted location for each reference pressure sensor of the network. The adjusted location and the reference-level pressure for each reference pressure sensor are used to determine a pressure pattern, which is used to determine a reference-level pressure value for the estimated position of the mobile device. The reference-level pressure value is used for calibrating a pressure sensor of the mobile device, or for estimating an altitude of the mobile device for emergency response or navigation.

Abstract: Systems and methods for pairing a payment object reader with a computing device are described. An example method includes detecting, by a computing device and while in a pairing mode, a plurality of payment object readers. Each of the plurality of payment object readers is configurable to be paired wirelessly with the computing device. Each of the plurality of payment object readers outputs a signal strength representative of a location of the payment object reader relative to the computing device. The computing device tracks respective signal strengths of the plurality of payment object readers over time. Based on a determination that a change in a signal strength of a particular payment object reader of the plurality of payment object readers represents movement of the particular payment object reader relative to the computing device, a wireless communication channel is established between the particular payment object reader and the computing device.

Abstract: Described is an apparatus of a User Equipment (UE) operable to communicate with an Evolved Node-B (eNB) on a wireless network. The apparatus may comprise a first circuitry, a second circuitry, and a third circuitry. The first circuitry may be operable to process a configuration transmission carrying a half-tone shifting indicator. The second circuitry may be operable to select one or more subcarrier frequencies for Uplink (UL) transmission based on the half-tone shifting indicator. The third circuitry may be operable to generate a UL transmission for the one or more subcarrier frequencies. The half-tone shifting indicator may have a first value indicating application of a half-subcarrier offset, and a second value indicating no application of the half-subcarrier offset.

Abstract: A method to identify a problematic 2D position of a mobile device can include: determining a reported 2D position of the mobile device; determining a piece of information about the mobile device; and comparing the reported 2D position and the piece of information about the mobile device. Upon determining that the reported 2D position and the piece of information about the mobile device are consistent with each other, the reported 2D position of the mobile device is used as an estimate of the actual 2D position of the mobile device, or upon determining that the reported 2D position and the piece of information about the mobile device are not consistent with each other, the reported 2D position is determined to be problematic, and the reported 2D position of the mobile device is removed from a list of reported 2D positions of the mobile device.

Abstract: Systems, methods, and computer program products identify arrhythmias experienced by a patient. A system includes an external wearable heart monitoring device for continuous and long-term monitoring of a patient that includes electrocardiogram (ECG) electrodes and circuitry to sense surface ECG activity and provide ECG channel(s) producing ECG signal(s), a non-transitory computer-readable medium including an arrhythmia classifier including neural network(s), and processor(s). The neural network(s) are trained based on a historical collection of ECG signal portions with annotation data including at least one annotation for each ECG signal portion and based on weight data including a weight for each annotation based on the annotator thereof. The processor(s) receive the ECG signal(s), monitor the ECG signal(s) to detect at least one arrhythmia event based on the arrhythmia classifier, and transmit at least one communication based on the arrhythmia event(s) to a remote computer system.

Abstract: Provided herein are immune cells and methods of use, wherein the immune cells include a chimeric antigen receptor (CAR), wherein the CAR comprises an extracellular antigen binding domain that binds specifically to a first epitope; and an inhibitory chimeric antigen receptor (iCAR), wherein the iCAR comprises an extracellular antigen binding domain that binds specifically to a second epitope, wherein the immune cell is activated when the immune cells binds to the first epitope and does not bind to the second epitope; and wherein the immune cell is inactivated when the immune cell binds to the first and second epitopes.

Abstract: A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 ?m to approximately 0.5 ?m, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.

Abstract: A windshield wiper system for a vehicle. In one example, the windshield wiper system includes a drive, a wiper, and a control device, which is connectable to a continuous power supply of the vehicle. The control device is configured to communicate with at least one control unit of the vehicle via a predefined data transfer system, and to control the drive to move the wiper arm based on specifications from the control unit. Another example relates to a method for controlling a windshield wiper system of a vehicle, where the system is configured to clean a windshield of the vehicle by means of at least one wiper. The method includes monitoring an environment of the vehicle, establishing a wiper mode for detected conditions in the environment of the vehicle, and controlling a drive of the windshield wiper system to move the wiper according to the wiper mode.

Abstract: A computer-implemented method according to one embodiment includes performing object detection on a frame to identify a set of objects within the frame, and determining a location of each object of the set of objects within the frame. The method further includes constructing a code tree structure for the frame. The code tree structure defines the determined locations. A rule defining modifications to make to at least some of the objects is received and the code tree structure is crawled. The rule is applied to the objects during the crawling. The method further includes layering the modifications defined in the rule on the set of objects within the frame. A computer program product according to another embodiment includes a computer readable storage medium having program instructions embodied therewith. The program instructions are readable and/or executable by a computer to cause the computer to perform the foregoing method.

Abstract: Provided are bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof, and methods for identifying such bivalent compounds.

Abstract: Computer-implemented methods, computer-readable storage media storing instructions and computer systems for labeling significant locations based on contextual data can be implemented to perform operations that include determining a location of a computing device, and determining a label for the determined location based on contextual data associated with the significant location. The location can be a significant location that has meaning to a user of the device.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed for electric motorized wheel assemblies. An example wheel assembly for use with an electric vehicle disclosed herein includes an electric motor, a suspension assembly, and a frame mounting interface to attach the wheel assembly to a frame of the electric vehicle.

Abstract: The present application is directed to a polymer comprising a moiety of formula: wherein X, Y, i, j, s, and k are as described herein and salts thereof and to a process of preparing such a polymer.

Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

Abstract: Extending the spatial coverage of a reference pressure network. Particular embodiments described herein include machines that initially determine that an estimated position of a mobile device resides outside a coverage area of a network of reference pressure sensors. Reference-level pressures corresponding to reference pressure sensors of the network are determined using measurements of pressure from the network of reference pressure sensors. A pressure pattern for a region that includes the estimated position and an area not included in the coverage area of the network is determined using reference-level pressures that were not determined using measurements of pressure from the network of reference pressure sensors. The reference-level pressures corresponding to reference pressure sensors of the network and the pressure pattern are used to determine a reference-level pressure value for use in calibrating a pressure sensor of the mobile device or for use in estimating an altitude of the mobile device.

Abstract: In a first aspect, the present invention is directed to a tire comprising a belt portion and a tread portion radially outward of the belt portion, wherein the tread portion comprises a radially outer tread layer for contacting the road when driving and a radially inner tread layer arranged between the radially outer tread layer and the belt portion, wherein the radially outer tread layer comprises a first rubber composition having a first shear storage modulus G?1 and the radially inner tread layer comprises a second rubber composition having a second shear storage modulus G?2, wherein the second shear storage modulus G?2 is between 3 MPa and 9 MPa higher than the first shear storage modulus G?1, and wherein the first shear storage modulus G?1 ranges from 1 MPa to 3 MPa and the second shear storage modulus G?2 ranges from 4 MPa to 12 MPa.