Abstract: Embodiments disclosed herein include needle-free syringe and cap assemblies and filling tub systems. One embodiment of filling tub system includes a filling tub having exterior walls and a floor. The floor is formed into a plurality of sockets configured to receive and support a plurality of cap and syringe body assemblies, with each cap and syringe assembly received in a separate socket. Furthermore, each socket is configured to receive and support a syringe and cap assembly with contact only between one or more surfaces of the socket and selected outer surfaces of the cap. Methods of pre-filling a quantity of needle-free syringes are also disclosed.

Abstract: The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria comprising contacting the one or more bacteria with a Mitrecin A polypeptide. The target bacteria can be selected from the group consisting of a Gram-positive bacterium, a Gram-negative bacterium, or both. In one embodiment, the present invention is drawn to a polynucleotide encoding a Mitrecin A polypeptide, a vector comprising the polynucleotide, a host cell comprising the polynucleotide, or a composition comprising the Mitrecin A polypeptide, the polynucleotide, the vector, or the host cell.

Abstract: CRISPR/Cas-related compositions and methods which provide for efficient gene editing of eukaryotic cells using modified gRNAs.

Abstract: Techniques are provided for locating and validating single-nucleotide polymorphism (SNP) islands by scanning a reference genome. A system scans a reference genome to locate a high-variance region containing at least a minimum number of known impactful SNP locations in less than a maximum length, wherein the high-variance region is flanked by low-variance regions of at least minimum length and each having fewer than a maximum number of known relevant SNP locations. The system allows for tuning maximum and minimum region lengths, maximum and minimum SNP-location quantities, and rate-of-occurrence thresholds that define relevant and/or impactful SNP locations. Primers are designed for portions of the low-variance regions that are unique within the reference genome, wherein the primers amplify for the high-variance region.

Abstract: Embodiments disclosed herein include needle-free syringe and cap assemblies and filling tub systems. One embodiment of filling tub system includes a filling tub having exterior walls and a floor. The floor is formed into a plurality of sockets configured to receive and support a plurality of cap and syringe body assemblies, with each cap and syringe assembly received in a separate socket. Furthermore, each socket is configured to receive and support a syringe and cap assembly with contact only between one or more surfaces of the socket and selected outer surfaces of the cap. Methods of pre-filling a quantity of needle-free syringes are also disclosed.

Abstract: The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria comprising contacting the one or more bacteria with a Mitrecin A polypeptide. The target bacteria can be selected from the group consisting of a Gram-positive bacterium, a Gram-negative bacterium, or both. In one embodiment, the present invention is drawn to a polynucleotide encoding a Mitrecin A polypeptide, a vector comprising the polynucleotide, a host cell comprising the polynucleotide, or a composition comprising the Mitrecin A polypeptide, the polynucleotide, the vector, or the host cell.

Abstract: A microscopic collection device, method for collecting a microscopic sample from a target surface, and the work stand for holding the microscopic collection device are provided. The microscopic collection device includes a holding element comprising a handle at one end and a collection platform connected to the holding element at a second end. The collection platform includes a collection surface on which the microscopic sample is deposited when the microscopic collection device comes into contact with the target surface. A tape is inserted through a slit and wrapped around the collection platform. The work stand includes a slit capable of holding the microscopic collection device such that the collection platform is perpendicular to the top surface of the work stand. A microscopic sample, collected using the microscopic collection device, is not only collected from the target surface but is also concentrated onto the collection face of the tape.

Abstract: Removable fiber management sections for fiber optic housings, and related components and methods are disclosed. In one embodiment, a fiber optic system is provided. The fiber optic system comprises a fiber optic housing defining at least one interior chamber configured to support fiber optic equipment. The fiber optic system also comprises a removable front section connected to the fiber optic housing and defining at least one front section interior chamber coupled to the at least one interior chamber of the fiber optic housing. The removable front section is configured to support at least one fiber management device to manage one or more fibers connected to fiber optic equipment disposed in the enclosure. In another embodiment, a method of managing optical fiber in a fiber optic system is provided.

Abstract: The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria comprising contacting the one or more bacteria with a Mitrecin A polypeptide. The target bacteria can be selected from the group consisting of a Gram-positive bacterium, a Gram-negative bacterium, or both. In one embodiment, the present invention is drawn to a polynucleotide encoding a Mitrecin A polypeptide, a vector comprising the polynucleotide, a host cell comprising the polynucleotide, or a composition comprising the Mitrecin A polypeptide, the polynucleotide, the vector, or the host cell.

Abstract: A vial adapter for a needle-free injection syringe and methods of filling a needle-free syringe from a vial of injectable fluid. One vial adapter embodiment includes a housing and a compliant valve. The housing includes a central divider located between a vial opening and a needle-free syringe opening. The housing also includes a hollow center post extending from the central divider toward the needle-free syringe opening and a hollow filling needle extending from the central divider toward the vial opening. Together, the filling needle and center post provide for fluid communication between the vial opening and the needle-free syringe opening. The compliant valve includes a surface forming a fluid tight seal with the central divider and an inner passageway. In addition, a syringe sealing surface provides for a fluid tight seal with a needle-free syringe placed into contact with the compliant valve.

Abstract: The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria comprising contacting the one or more bacteria with a Mitrecin A polypeptide. The target bacteria can be selected from the group consisting of a Gram-positive bacterium, a Gram-negative bacterium, or both. In one embodiment, the present invention is drawn to a polynucleotide encoding a Mitrecin A polypeptide, a vector comprising the polynucleotide, a host cell comprising the polynucleotide, or a composition comprising the Mitrecin A polypeptide, the polynucleotide, the vector, or the host cell.

Abstract: A fiber optic apparatus including a retainer assembly having at least one retainer configured to toollessly, releasably retain a fiber body and or one or more optical fibers is disclosed. An attachment feature may toollessly, removably attach the retainer assembly to a mounting surface. The at least one retainer is configured to releasably retain the fiber body via mounting bosses on the fiber body. A stacking feature may be configured to removably attach a second retainer assembly to the retainer assembly. The at least one retainer may be configured to releasably retain the one or more optical fibers to strain relief the one of more optical fibers. The mounting surface may be fiber optic equipment. The fiber optic equipment may be a shelf mounted to a chassis in a fiber optic equipment rack.

Abstract: The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria comprising contacting the one or more bacteria with a Mitrecin A polypeptide. The target bacteria can be selected from the group consisting of a Gram-positive bacterium, a Gram-negative bacterium, or both. In one embodiment, the present invention is drawn to a polynucleotide encoding a Mitrecin A polypeptide, a vector comprising the polynucleotide, a host cell comprising the polynucleotide, or a composition comprising the Mitrecin A polypeptide, the polynucleotide, the vector, or the host cell.

Abstract: An adapter housing for receiving a plurality of multi-fiber connectors includes a rectangular, box-like housing structure having opposing side walls and a back wall that to adapted to mount in a 2-U space in an equipment rack, wherein the housing structure has a width of no greater than about 17.75 inches and a height of no greater than about 3.50 inches. A bank of adapters is provided for receiving multi-fiber connectors. The bank of adapters includes individual connector-adapter-connector locations that together receive at least 200 multi-fiber connector pairs within the housing structure.

Abstract: Removable strain relief brackets for securing fiber optic cables and/or optical fiber to fiber optic equipment, and related assemblies and methods are disclosed. The removable strain relief brackets may be employed to secure fiber optic cable and/or optical fibers routed to fiber optic equipment. The removable strain relief brackets may also be employed to provide strain relief for fiber optic cable and/or optical fibers routed and secure to fiber optic equipment. Fiber optic cable discussed herein includes optical fiber whether disposed in a common cable jacket or disposed freely of each other outside a cable jacket.

Abstract: A vial adapter for a needle-free injection syringe and methods of filling a needle-free syringe from a vial of injectable fluid. One vial adapter embodiment includes a housing and a compliant valve. The housing includes a central divider located between a vial opening and a needle-free syringe opening. The housing also includes a hollow center post extending from the central divider toward the needle-free syringe opening and a hollow filling needle extending from the central divider toward the vial opening. Together, the filling needle and center post provide for fluid communication between the vial opening and the needle-free syringe opening. The compliant valve includes a surface forming a fluid tight seal with the central divider and an inner passageway. In addition, a syringe sealing surface provides for a fluid tight seal with a needle-free syringe placed into contact with the compliant valve.

Abstract: An adapter housing for receiving a plurality of multi-fiber connectors includes a rectangular, box-like housing structure having opposing side walls and a back wall that to adapted to mount in a 2-U space in an equipment rack, wherein the housing structure has a width of no greater than about 17.75 inches and a height of no greater than about 3.50 inches. A bank of adapters is provided for receiving multi-fiber connectors. The bank of adapters includes individual connector-adapter-connector locations that together receive at least 200 multi-fiber connector pairs within the housing structure.

Abstract: There is provided fiber drop terminal (“FDT”) assemblies for providing selective connections between optical fibers of distribution cables and optical fibers of drop cables, such as in multiple dwelling units. The FDT assemblies include a base and a cover that define a tongue and groove that selectively engage to seal the base and cover. The FDT assemblies also include a mounting plate for mounting of the base and cover, as well as a mounting plate extension for mounting of a skirt. The skirt provides slack storage for drop cables exiting the FDT. The components of the FDT assembly are selectively interlockable to prevent unauthorized access to the interior cavity of the base and cover and to the slack storage area of the skirt.

Abstract: The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent growth of one or more bacteria comprising contacting the one or more bacteria with a Mitrecin A polypeptide. The target bacteria can be selected from the group consisting of a Gram-positive bacterium, a Gram-negative bacterium, or both. In one embodiment, the present invention is drawn to a polynucleotide encoding a Mitrecin A polypeptide, a vector comprising the polynucleotide, a host cell comprising the polynucleotide, or a composition comprising the Mitrecin A polypeptide, the polynucleotide, the vector, or the host cell.