Abstract: A transdermal reservoir and a method of the present invention for loading a material into a reservoir includes providing an reservoir including a backing with an interior surface comprising a bibulous reservoir having a patient contact surface with a shape disposed on the interior surface of the backing. The method includes providing a closure sized and shaped to engage the backing for forming a releasable seal to isolate the bibulous reservoir from the ambient environment, the closure is removable from the housing to expose the patient contact surface for use. The provided closure has an inside surface with a section of an absorbent material disposed thereon. The provided section has a first surface so that when the closure is disposed on the backing, the absorbent material first surface is positioned in intimate physical contact with the reservoir. The method includes applying an aliquot of a material to the absorbent material.

Abstract: A transdermal reservoir and method for loading a material into a reservoir includes providing a bibulous reservoir blocking a backing with an interior surface having a patient contact surface with a shape disposed on the interior surface of the backing. A closure is sized and shaped to engage the backing for forming a releasable seal to isolate the bibulous reservoir from the ambient environment. The closure has an inside surface with a section of an absorbent material disposed thereon. When the closure is disposed on the backing, the absorbent material is positioned in intimate physical contact with the reservoir. The method includes applying an aliquot of a material to the absorbent material,. placing the closure on the backing so that the absorbent material is in intimate physical contact with the contact surface of the bibulous reservoir and the closure forms the releasable seal with the backing.

Abstract: An iontophoretic drug delivery system including a plurality of patches, at least one reusable controller and a unit for storing and dispensing the patches. The patches may be secured in a compartment formed in the unit and the controller may be stored in another compartment formed in the unit. In this way, the reusable controller and a new patch can be removed from the unit and fastened to one another for activation and attachment to the skin of a patient.

Abstract: The user activated iontophoretic device of the present invention includes a disposable patch and a reusable controller. The patch contains an electrode assembly, an electrode reservoir and at least one drug reservoir. The patch is divided or otherwise separated into at least two portions, with one portion containing the electrode reservoir and the other containing the drug reservoir, which may include a medication in a dry form. The electrode reservoir and the drug reservoir are sealingly separated by a barrier, which can be manipulated to bring the reservoirs into fluid conducting contact with one another. A method of activating the device includes causing the two portions to rotate about a central axis relative to one another to manipulate the barrier and bring the reservoirs into fluid conducting contact with one another to at least partially hydrate one of the reservoirs. In this way, the device is suitable for use to deliver a drug which has limited stability in an aqueous solution.

Abstract: A user activated iontophoretic device of the present invention includes an electrode assembly, an electrode reservoir and at least one drug reservoir. The device is divided or otherwise separated into at least two portions, with one portion containing the electrode reservoir and the other containing the drug reservoir, which may include a medication in a dry form. The electrode reservoir and the drug reservoir are sealingly separated by a barrier, which can be removed to bring the reservoirs into fluid conducting contact with one another. A method of activating the device includes causing the two portions to come into fluid conducting contact with one another to at least partially hydrate one of the reservoirs. This can be accomplished by removing the barrier dividing the two portions. In this way, the device is suitable for use to deliver a drug which has limited stability in an aqueous solution.

Abstract: An iontophoretic drug delivery system including a patch, a controller and a magazine. The patch may be secured in a compartment formed in the magazine so that upon insertion of the controller along the magazine to fasten the controller to the patch, a dry drug contained in the patch is hydrated and the patch and controller can be removed from the magazine for attachment to the skin of a patient.