Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; a delivery passageway (34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 ?m=<10%.

Abstract: The present invention provides a dry powder inhaler comprising: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; and a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, wherein the formulation comprises an inhalable ?2-agonist having a particle size distribution of d1O<1 ???=1-3 ???, d90=3.5-6 ?m and NLT 99% 10 ?m and a lactose carrier.

Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; a delivery passageway (34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 ?m=<10%.

Abstract: Described herein is a dry powder inhaler which includes: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, and an inhalable ?2-agonist having a particle size distribution of d10<1 ?m, d50=1-3 ?m, d90=3.5-6 ?m and NLT 99% 10 ?m and a lactose carrier.

Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; a delivery passageway (34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 um=<10%.

Abstract: A deflecting prism for electromagnetic radiation, in particular for refractometer- and/or ATR-measurements, is part of a measuring configuration. The deflecting prism has a body produced in one piece from a mono-crystal. The body has at least two beam conductive surfaces on a side of the body opposite each other or circumferentially about the body and a measuring surface lying between the beam conductive surfaces or surrounded by the latter. The body further has at least one beam entry surface or a beam exit surface. Accordingly, the measuring surface lies on an elevation formed on the body, which crosses over via a ledge surrounding the elevation into the remaining part of the body. On the remaining part, the beam conductive surfaces and/or the beam entry surface or exit surface lie.

Abstract: The present invention provides a dry powder inhaler comprising: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; and a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, wherein the formulation comprises an inhalable ?2-agonist having a particle size distribution of d10<1 ?m, d50=1-3 ?m, d90=3.5-6 ?m and NLT 99% 10 ?m and a lactose carrier.

Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: •a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; •a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; •a delivery passageway/34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, •wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 um=<10%.

Abstract: A deflecting prism for electromagnetic radiation, in particular for refractometer- and/or ATR-measurements, is part of a measuring configuration. The deflecting prism has a body produced in one piece from a mono-crystal. The body has at least two beam conductive surfaces on a side of the body opposite each other or circumferentially about the body and a measuring surface lying between the beam conductive surfaces or surrounded by the latter. The body further has at least one beam entry surface or a beam exit surface. Accordingly, the measuring surface lies on an elevation formed on the body, which crosses over via a ledge surrounding the elevation into the remaining part of the body. On the remaining part, the beam conductive surfaces and/or the beam entry surface or exit surface lie.

Abstract: An ATR sensor has a housing and sensor components in the housing including an electromagnetic radiation source for emitting a predefined wavelength range, a reflection body permeable for radiation and contactable with a fluid to be evaluated, and a detector for the reflected radiation as well as other members for conducting the measurement and for operation. The sensor is particularly suited for measuring a CO2 content of a fluid. Before sealing the housing in a gas-tight manner, in particular for avoiding a measurement value drift and for keeping the radiation paths free of CO2, a CO2 getter material is introduced into the housing and/or into a receiving space of an additional housing that communicates with the interior space of the housing before sealing the interior space and/or the receiving space.