Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.

Abstract: A galley cart has a rear wall with an inlet port and an outlet port. A first divider has a first edge, wherein a first distance is defined between the first edge and a front wall. A second divider has a second edge, wherein a second distance is defined between the second edge and the front wall. The second distance is less than the first distance for control of the flow of cooling air.

Abstract: A galley for an aircraft includes a frame having metal structural members having interior surfaces and panels coupled to and supported by the frame. Each panel has a core and a facesheet having an inner surface. The frame and the panels define a cart compartment configured to receive a galley cart. The interior surfaces of the metal structural members are interior of the inner surface of the corresponding facesheet. The galley includes a cooling system having a supply duct and a return duct along one or more of the panels in flow communication with the cart compartment configured to supply cooled airflow from a heat exchanger. The galley includes insulating panels located in the cart compartment covering the interior surfaces of the corresponding metal structural members.

Abstract: A screw actuator, includes: a screw comprising a first helical contact surface and a first helical raceway surface; a nut comprising a second helical contact surface and a second helical raceway surface; and a plurality of ball bearings in a helical raceway formed by the first helical raceway surface and the second helical raceway surface. When the screw is loaded relative to the nut in a first axial direction, the first helical contact surface is compressed against the second helical contact surface. When the screw is loaded relative to the nut in a second axial direction, the plurality of ball bearings are compressed between the first helical raceway surface and the second helical raceway surface.

Abstract: A galley cart has a rear wall with an inlet port and an outlet port. A first divider has a first edge, wherein a first distance is defined between the first edge and a front wall. A second divider has a second edge, wherein a second distance is defined between the second edge and the front wall. The second distance is less than the first distance for control of the flow of cooling air.

Abstract: A system and method for monitoring a passenger requiring assistance during travel, such as an unaccompanied minor, a disabled passenger, or an elderly passenger, on a common carrier. The system includes a machine-readable tag such as a Quick Response code (QR code) or a RFID tag that references passenger information, including itinerary information. A first mobile device of a first agent decodes the QR code to present the unaccompanied minor information. A second mobile device of a second agent decodes the QR code to present the unaccompanied minor information. In one embodiment, the QR code includes a uniform resource locator (URL) for accessing the passenger information and the first and second agents can authorize and accept the transfer of the unaccompanied minor by interfacing with a user interface.

Abstract: A galley for an aircraft includes a frame having metal structural members having interior surfaces and panels coupled to and supported by the frame. Each panel has a core and a facesheet having an inner surface. The frame and the panels define a cart compartment configured to receive a galley cart. The interior surfaces of the metal structural members are interior of the inner surface of the corresponding facesheet. The galley includes a cooling system having a supply duct and a return duct along one or more of the panels in flow communication with the cart compartment configured to supply cooled airflow from a heat exchanger. The galley includes insulating panels located in the cart compartment covering the interior surfaces of the corresponding metal structural members.

Abstract: A screw actuator, includes: a screw comprising a first helical contact surface and a first helical raceway surface; a nut comprising a second helical contact surface and a second helical raceway surface; and a plurality of ball bearings in a helical raceway formed by the first helical raceway surface and the second helical raceway surface. When the screw is loaded relative to the nut in a first axial direction, the first helical contact surface is compressed against the second helical contact surface. When the screw is loaded relative to the nut in a second axial direction, the plurality of ball bearings are compressed between the first helical raceway surface and the second helical raceway surface.

Abstract: A light projection device includes a mixing tube having an open exit end, and a plurality of light sources, each of the plurality of light sources positioned to emit a light stream toward the open exit end of the mixing tube. A diffuser is disposed between the plurality of light sources and the open exit end of the mixing tube, the diffuser configured to diffuse at least one light stream from the plurality of light sources into a diffused light stream. A template is positioned proximate the open exit end of the mixing tube and configured to shape the diffused light stream from the diffuser into a patterned light stream.

Abstract: A light projection device includes a mixing tube having an open exit end, and a plurality of light sources, each of the plurality of light sources positioned to emit a light stream toward the open exit end of the mixing tube. A diffuser is disposed between the plurality of light sources and the open exit end of the mixing tube, the diffuser configured to diffuse at least one light stream from the plurality of light sources into a diffused light stream. A template is positioned proximate the open exit end of the mixing tube and configured to shape the diffused light stream from the diffuser into a patterned light stream.

Abstract: A system for cooling a thermally insulated galley cart in an aircraft incorporates a skin heat exchanger configured to transfer heat to an aircraft skin. A cooling system is in communication with the skin heat exchanger and is configured to be removably coupled with a thermally insulated galley cart.

Abstract: A storage container incorporates a housing defining a cavity therein. At least one support rail extends from the housing within the cavity having a plurality of encoded first moieties. At least one refrigerant brick having mating encoded second moieties configured to be received into the encoded first moieties couples the refrigerant brick within the cavity.

Abstract: A system for cooling a thermally insulated galley cart in an aircraft incorporates a skin heat exchanger configured to transfer heat to an aircraft skin. A cooling system is in communication with the skin heat exchanger and is configured to be removably coupled with a thermally insulated galley cart.

Abstract: A galley cart has a rear wall with an inlet port and an outlet port. A first divider has a first edge, wherein a first distance is defined between the first edge and a front wall. A second divider has a second edge, wherein a second distance is defined between the second edge and the front wall. The second distance is less than the first distance for control of the flow of cooling air.

Abstract: A system and method for monitoring a passenger requiring assistance during travel, such as an unaccompanied minor, a disabled passenger, or an elderly passenger, on a common carrier. The system includes a machine-readable tag such as a Quick Response code (QR code) or a RFID tag that references passenger information, including itinerary information. A first mobile device of a first agent decodes the QR code to present the unaccompanied minor information. A second mobile device of a second agent decodes the QR code to present the unaccompanied minor information. In one embodiment, the QR code includes a uniform resource locator (URL) for accessing the passenger information and the first and second agents can authorize and accept the transfer of the unaccompanied minor by interfacing with a user interface.

Abstract: A storage container incorporates a housing defining a cavity therein. At least one support rail extends from the housing within the cavity having a plurality of encoded first moieties. At least one refrigerant brick having mating encoded second moieties configured to be received into the encoded first moieties couples the refrigerant brick within the cavity.

Abstract: Novel N-phenyl-N'benzoylureas which are useful as insecticides and acaricides.

Abstract: Novel N-phenyl-N'benzoylureas which are useful as insecticides and acaricides.