Abstract: The mice of this invention heritably carry alpha-1-acid glycoprotein (AGP) genes which may be introduced by the transgenic methodology. These animal models are useful for various purposes including 1) assessment of the in vivo role of AGP in the clearance of individual drugs; 2) assessment of the influence of AGP on the pharmacological activity of individual drugs; 3) testing of hypotheses concerning the function of AGP; and 4) identification of the AGP gene cis-acting regulatory features.

Abstract: The distinguishing feature of so-called no break or non-interrupting power supplies over ordinary standby or emergency power systems is that no supply interruption (even momentary) occurs when the commercial power source fails or when commercial power again becomes available. This invention comprises a non-interrupting modular power supply system which can be configured for loads of from 15 to 100, watts or for 75 to 500 watts, respectively. The system combination supplies single or multiple regulated DC outputs meeting the requirements of the equipment being operated. A source of AC power is converted to DC for utilization by a load and for charging a back-up battery. When the source of AC power fails, the battery supplies power to the load. Means are provided to monitor the battery voltage to control its charging.

Abstract: Apparatus for controlling the intensity of a display on a cathode ray tube wherein the control signals are DC through several megahertz and a control loop maintains the average value of the control signal on the grid of a cathode ray tube relatively constant. Low frequency and high frequency signals are applied to the tube through separate circuits which are coupled together to provide coincident high pass and low pass -3 db crossover points so that all control signals applied to the tube are substantially equal over the entire bandwidth.