Patents by Inventor Michael J. Finney
Michael J. Finney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10724084Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: GrantFiled: December 28, 2018Date of Patent: July 28, 2020Assignee: Bio-Rad Laboratories, Inc.Inventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Patent number: 10669576Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: GrantFiled: September 27, 2017Date of Patent: June 2, 2020Assignee: Bio-Rad Laboratories, Inc.Inventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Publication number: 20190136297Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: ApplicationFiled: December 28, 2018Publication date: May 9, 2019Inventors: Igor KORDUNSKY, Jeffrey A. GOLDMAN, Michael J. FINNEY
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Publication number: 20180171387Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: ApplicationFiled: September 27, 2017Publication date: June 21, 2018Applicant: Bio-Rad Laboratories, Inc.Inventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Publication number: 20150152475Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: ApplicationFiled: September 8, 2014Publication date: June 4, 2015Applicant: Bio-Rad LaboratoriesInventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Patent number: 8835118Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: GrantFiled: July 5, 2012Date of Patent: September 16, 2014Assignee: Bio-Rad Laboratories, Inc.Inventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Publication number: 20130143308Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: ApplicationFiled: July 5, 2012Publication date: June 6, 2013Applicant: Bio-Rad LaboratoriesInventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Patent number: 8236504Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: GrantFiled: June 30, 2010Date of Patent: August 7, 2012Assignee: Bio-Rad Laboratories, Inc.Inventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Publication number: 20110160073Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: ApplicationFiled: June 30, 2010Publication date: June 30, 2011Applicant: Bio-Rad LaboratoriesInventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Patent number: 7749736Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: GrantFiled: November 1, 2006Date of Patent: July 6, 2010Assignee: Bio-Rad LabortoriesInventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Patent number: 7148043Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: GrantFiled: May 8, 2003Date of Patent: December 12, 2006Assignee: Bio-Rad Laboratories, Inc.Inventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Publication number: 20040224317Abstract: A fluorescence detection apparatus for analyzing samples located in a plurality of wells in a thermal cycler and methods of use are provided. In one embodiment, the apparatus includes a support structure attachable to the thermal cycler and a detection module movably mountable on the support structure. The detection module includes one or more channels, each having an excitation light generator and an emission light detector both disposed within the detection module. When the support structure is attached to the thermal cycler and the detection module is mounted on the support structure, the detection module is movable so as to be positioned in optical communication with different ones of the plurality of wells. The detection module is removable from the support structure to allow easy replacement.Type: ApplicationFiled: May 8, 2003Publication date: November 11, 2004Applicant: MJ ResearchInventors: Igor Kordunsky, Jeffrey A. Goldman, Michael J. Finney
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Patent number: 6682641Abstract: The invention provides an electrophoresis cassette to cast electrophoresis gels and to separate and analyze molecular components by electrophoresis. The electrophoresis cassette comprises a top plate assembly, a spacer and a bottom plate. The top plate assembly is seated to the bottom plate with the spacer there between to define a thickness of the electrophoresis cassette and to seal an outer perimeter of the assembly. The top plate assembly includes a cathode reservoir connected to a first terminal end of a central plate, and an anode reservoir connected to a second terminal end of the central plate. When the electrophoresis cassette is assembled, the cathode and anode reservoirs are in alignment with the first and second terminal ends of the central plate to facilitate formation of leak-proof seals between the reservoirs and the assembly components.Type: GrantFiled: April 26, 2000Date of Patent: January 27, 2004Assignee: MJ Research, Inc.Inventors: Michael J. Finney, Daniel E. Sullivan, Bruce R. Turner, Alexis Vira, Peter B. Vander Horn, Charles P. Andre, Sean Rubin, Corey Nislow, John R. Linton, William D. Bowers
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Publication number: 20020006619Abstract: A thermal cycler for use in thermal cycling procedures, and more specifically to a thermal cycler and a method for using same which permits the creation of temperature gradients in the thermal cycler in either of two dimensions and which permits optimization of the hold time of a given step in the thermal cycling procedureType: ApplicationFiled: February 23, 2001Publication date: January 17, 2002Inventors: David Cohen, Michael J. Finney, Michael Mortillaro
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Patent number: 6004512Abstract: A sample cartridge block that includes a first plate, a second plate and a third plate. The third plate is thermally connected to the first plate and the second plate. In some embodiments, the block is capable of holding a relatively high density of sample cartridges. In certain embodiments, the block provides good sample temperature stability while the sample temperature is held constant or while the sample temperature is being changed. According to the invention, a sample block may include one material or more than one material. Preferably, a sample cartridge block has a relatively low thermal mass. In some embodiments, the first plate of a sample cartridge block may have a larger surface area than the surface area of the third plate. According to the present invention, the first plate of the sample cartridge block may be thermally connected to a temperature controller. In certain embodiments, a sample cartridge block may have a relatively large surface area in contact with a temperature controller.Type: GrantFiled: December 8, 1995Date of Patent: December 21, 1999Assignee: MJ ResearchInventors: Paul Titcomb, Michael J. Finney, David Cohen
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Patent number: 5721136Abstract: A sheet of material seals vessels for biochemical reactions which undergo thermal cycling, and comprises a multilayer composite sheet which is placed over the openings of one or more reaction vessels. The multilayer composite sheet material has at least two layers, one layer providing strength and integrity to the material and the second layer being relatively thick comprising a deformable substance with a tacky surface to contact and seal vessels for biochemical reactions.Type: GrantFiled: November 9, 1994Date of Patent: February 24, 1998Assignee: MJ Research, Inc.Inventors: Michael J. Finney, Paul Titcomb
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Patent number: 5011586Abstract: A gel electrophoresis apparatus for separating DNA molecules of high molecular weight having means for generating at least two electric fields oriented transversely to each other, and a gel box, shaped, and contoured to simultaneously form both the electric fields into uniform electric fields.Type: GrantFiled: December 23, 1988Date of Patent: April 30, 1991Assignee: MJ Research, Inc.Inventors: John D. Finney, Michael J. Finney