Abstract: Disclosed herein are compounds that inhibit cullin-RING E3 ubiquitin ligase 4, a method of inhibiting the catalytic activity of a Cullin-RING E3 Ubiquitin (Ub) Ligase (CRL) in a cell, compositions comprising the inhibitor compounds, a method of treating a tumor, and a method of treating a subject for cancer.

Abstract: Devices, systems, and methods for making and using highly sustainable circuit assemblies are disclosed herein. In various aspects, the highly sustainable circuit assembly includes a substrate layer; and a pattern of contact points supported by the substrate layer. The pattern of contact points can be configured to correspond to at least one terminal of an electrical component. The pattern of contact points can include a deformable conductive material. The deformable conductive material can be a non-hazardous, readily reclaimable, readily recyclable material.

Abstract: An absorbent article can have a topsheet layer, a liquid impermeable layer, and an absorbent core positioned between the topsheet layer and the liquid impermeable layer. The absorbent article can further include an exudate management layer in fluid communication with the topsheet layer. In various embodiments, the exudate management layer can be positioned on a body facing surface of the topsheet layer. In various embodiments, the exudate management layer can be positioned between the topsheet layer and the absorbent core. The exudate management layer has a first component which defines an opening for direct passage of body exudates into the absorbent core. The exudate management layer has a second component which at least partially overlaps the first component of the exudate management layer and further extends in the longitudinal direction of the absorbent article in a direction towards the posterior region of the absorbent article.

Abstract: A method used in forming a memory array comprising strings of memory cells comprises forming a stack comprising vertically-alternating first tiers and second tiers. A channel-material string is in individual channel openings in the vertically-alternating first tiers and second tiers. A conductor-material contact is in the individual channel openings directly against the channel material of individual of the channel-material strings. The conductor-material contacts are vertically recessed in the individual channel openings. A conductive via is formed in the individual channel openings directly against the vertically-recessed conductor-material contact in that individual channel opening. Other aspects, including structure independent of method, are disclosed.

Abstract: A circuit assembly may include a substrate and a pattern of contact points formed from deformable conductive material supported by the substrate. The assembly may further include an electric component supported by the substrate and having terminals arranged in a pattern corresponding to the pattern of contacts points. The one or more of the terminals of the electric component may contact one or more of the corresponding contact points to form one or more electrical connections between the electric component and the contact points.

Abstract: A headlamp includes a strap, a bracket coupled to the strap, and a light assembly including a housing enclosing a light source and a battery for providing power to the light source. A magnetic interface is configured to removably couple the light assembly to the bracket. The magnetic interface includes a first magnetic element fixed to the bracket, and a second magnetic element fixed to the light assembly. The first magnetic element and the second magnetic element are configured to produce a magnetic attractive force to retain the light assembly relative to the bracket.

Abstract: A headlamp includes a strap, a bracket coupled to the strap, and a light assembly including a housing enclosing a light source and a battery for providing power to the light source. A magnetic interface is configured to removably couple the light assembly to the bracket. The magnetic interface includes a first magnetic element fixed to the bracket, and a second magnetic element fixed to the light assembly. The first magnetic element and the second magnetic element are configured to produce a magnetic attractive force to retain the light assembly relative to the bracket.

Abstract: A portable light including an elongated housing having a first end and a second end opposite the first end, and a light-emitting head pivotably coupled to the second end of the elongated housing. The light-emitting head having a housing portion defining a first end and a second end opposite the first end. A first light source is coupled to a first side of the light-emitting head and is positioned between the first end and the second end of the housing portion. A second light source coupled to the second end of the housing portion. A battery cell is removably coupled to the elongated housing to power the first and second light sources.

Abstract: A portable light including an elongated housing having a first end and a second end opposite the first end, and a light-emitting head pivotably coupled to the second end of the elongated housing. The light-emitting head having a housing portion defining a first end and a second end opposite the first end. A first light source is coupled to a first side of the light-emitting head and is positioned between the first end and the second end of the housing portion. A second light source coupled to the second end of the housing portion. A battery cell is removably coupled to the elongated housing to power the first and second light sources.

Abstract: A headlamp includes a strap, a bracket coupled to the strap, and a light assembly including a housing enclosing a light source and a battery for providing power to the light source. A magnetic interface is configured to removably couple the light assembly to the bracket. The magnetic interface includes a first magnetic element fixed to the bracket, and a second magnetic element fixed to the light assembly. The first magnetic element and the second magnetic element are configured to produce a magnetic attractive force to retain the light assembly relative to the bracket.

Abstract: A hygienic toothpaste dispenser comprises a main body member having a plurality of tubular spouts (27, 28, and 29), from which an individual can dispense toothpaste from his or her own personally assigned tubular spout permanently marked by indicia (30), thereby providing a sanitary delivery system. This dispenser has a main body with a base (23) for connection to a toothpaste container (20), either directly or via an adapter (FIG. 10), and tubular spouts with caps (31) for delivery of the paste. Additional dispenser embodiments (FIGS. 8A, 8B, and 9) are shown. Also additional adapter embodiments (FIGS. 11A, 11B, 11C, 12, 13, 14, 15, 16, and 17) show various means of connection between various types of toothpaste container tubular spouts and the various types of bases of the main body of the dispenser. Several dispensers may be connected together (FIG. 4), providing almost an unlimited number of assignable tubular spouts, limited only by a reasonable length and a reasonable width.