Abstract: A medical device is provided that comprises: (i) an expandable capsule that can be swallowed by a patient and positioned to a target tissue within the patient, (ii) an endoscope attached to the capsule for obtaining an image of the target tissue at a wavelength of interest, and (iii) a thin tube or wire configured to position the device to the target tissue. The thin tube or wire is expandable. The capsule can be swallowed in stages to position the device at different locations within the gastrointestinal tract. The thin tube or wire can deliver electromagnetic radiation for visualization of the target tissue. The thin tube or wire can provide a passage of a biopsy device for access to the target tissue. In some instances, the capsule comprises a band which rotates around the capsule to clean the capsule. In some instances, the capsule collects multispectral or hyperspectral information.

Abstract: Disclosed is systems and methods of simulating IEDs and munitions with an SUAV. One embodiment is a simulation of an SUAV that is used to directly deliver an TED. Another embodiment is a simulation of an SUAV that delivers IEDs by placing, dropping, or launching them from the SUAV. Additionally, the SUAV may be used to deliver other simulated hazardous devices such biological or chemical weapons, distraction devices or contraband.

Abstract: The invention comprises devices and methods for carrying quantities of materials preferably fluids. The device of the invention is preferably a wearable garment such as, preferably a vest or poncho, with one or more bladders or compartments adapted to hold a fluid. Preferably the garment comprises fluid connections between the bladders. The connections allow for the distributing the load over the carrier, which is preferably a person. The invention is designed to be inexpensive to manufacture, capable of easy manufacture in large numbers, and, if desired, disposable or repurposed. The device significantly enhances the ability of an individual to provide water or other fluids or materials to individuals or groups such as families. Preferably the invention allows for the transport of potable water from a supply point to the point of end use with minimal or no discomfort to the wearer.

Abstract: The invention comprises devices and methods for carrying quantities of materials preferably fluids. The device of the invention is preferably a wearable garment such as, preferably a vest or poncho, with one or more bladders or compartments adapted to hold a fluid. Preferably the garment comprises fluid connections between the bladders. The connections allow for the distributing the load over the carrier, which is preferably a person. The invention is designed to be inexpensive to manufacture, capable of easy manufacture in large numbers, and, if desired, disposable or repurposed. The device significantly enhances the ability of an individual to provide water or other fluids or materials to individuals or groups such as families. Preferably the invention allows for the transport of potable water from a supply point to the point of end use with minimal or no discomfort to the wearer.

Abstract: The invention comprises devices and methods for carrying quantities of materials preferably fluids. The device of the invention is preferably a wearable garment such as, preferably a vest or poncho, with one or more bladders or compartments adapted to hold a fluid. Preferably the garment comprises fluid connections between the bladders. The connections allow for the distributing the load over the carrier, which is preferably a person. The invention is designed to be inexpensive to manufacture, capable of easy manufacture in large numbers, and, if desired, disposable or repurposed. The device significantly enhances the ability of an individual to provide water or other fluids or materials to individuals or groups such as families. Preferably the invention allows for the transport of potable water from a supply point to the point of end use with minimal or no discomfort to the wearer.

Abstract: The invention comprises devices and methods for carrying quantities of materials preferably fluids. The device of the invention is preferably a wearable garment such as, preferably a vest or poncho, with one or more bladders or compartments adapted to hold a fluid. Preferably the garment comprises fluid connections between the bladders. The connections allow for the distributing the load over the carrier, which is preferably a person. The invention is designed to be inexpensive to manufacture, capable of easy manufacture in large numbers, and, if desired, disposable or repurposed. The device significantly enhances the ability of an individual to provide water or other fluids or materials to individuals or groups such as families. Preferably the invention allows for the transport of potable water from a supply point to the point of end use with minimal or no discomfort to the wearer.

Abstract: The present invention provides a hyperspectral imaging system which demonstrates changes in tissue oxygen delivery, extraction and saturation during shock and resuscitation including an imaging apparatus for performing real-time or near real-time assessment and monitoring of shock, including hemorrhagic, hypovolemic, cardiogenic, neurogenic, septic or burn shock. The information provided by the hyperspectral measurement can deliver physiologic measurements that support early detection of shock and also provide information about likely outcomes.

Abstract: This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction), obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.

Abstract: Balloon probes, adapted for use in endoscopy and other medical procedures, are useful to obtain spectroscopic information reflected or emitted from a tissue of interest in the infrared spectral region. The information collected by the probe is useful in the diagnosis and treatment of disease. The invention also relates to methods utilizing these probes to analyze a surface of interest, in a minimally invasive manner, in connection with the diagnosis and treatment of disease.

Abstract: The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease, that incorporate hyperspectral or multispectral imaging.

Abstract: Balloon probes, adapted for use in endoscopy and other medical procedures, are useful to obtain spectroscopic information reflected or emitted from a tissue of interest in the infrared spectral region. The information collected by the probe is useful in the diagnosis and treatment of disease. The invention also relates to methods utilizing these probes to analyze a surface of interest, in a minimally invasive manner, in connection with the diagnosis and treatment of disease.

Abstract: A non-invasive analyte monitoring instrument has a radiation source for directing excitation radiation to a portion of a surface of a tissue wherein said source emits radiation at a plurality of different wavelengths that excites a target in said tissue causing said target to emit radiation such that the radiation received at the surface provides an analyte level indication of the patient. A radiation detector positioned to receive radiation emitted from the surface wherein said radiation detector is configured to synchronously scan radiation emitted by the target with the excitation radiation.

Abstract: Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

Abstract: Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

Abstract: The invention is directed to imaging apparatus for performing real-time or near real-time assessment and monitoring. Embodiments of the device are useful in a plurality of settings including surgery, clinical procedures, tissue assessment, diagnostic procedures, forensic, health monitoring and medical evaluations.

Abstract: This invention relates to portable imaging devices, such as hyperspectral imaging devices, useful for forensic and other analysis, and methods for using these devices. Devices of the present invention provide images and patterned data arrays representing images in multiple discrete spectra that can then be summed or processed to allow for detection of patterns or anomalies in the data collected.

Abstract: Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

Abstract: Balloon probes, adapted for use in endoscopy and other medical procedures, are useful to obtain spectroscopic information reflected or emitted from a tissue of interest in the infrared spectral region. The information collected by the probe is useful in the diagnosis and treatment of disease. The invention also relates to methods utilizing these probes to analyze a surface of interest, in a minimally invasive manner, in connection with the diagnosis and treatment of disease.

Abstract: Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.