Abstract: A system may include a vehicle. The vehicle may include an array of haptic devices. The system may further include at least one processor configured to: determine a location of an object or occurrence relative to the user; based at least on the location of the object or occurrence relative to the user, select at least one haptic device of the array of haptic devices to be driven and function as a directional haptic alert to the user, wherein the directional haptic alert is indicative of a direction from the user toward the object or occurrence; and output at least one command to cause a driving of the selected at least one haptic device, wherein the driving of the selected at least one haptic device is perceivable by the user as the directional haptic alert.

Abstract: The present disclosure provides antibodies to V-domain Ig-containing Suppressor of T cell Activation (VISTA) and compositions comprising such antibodies. Also provided are methods of using antibodies that specifically binds to VISTA to treat diseases, e.g., to treat cancer.

Abstract: A wire termination system includes a heat applicator device to apply resistive heating to a specific connector pin of an electrical connector for the soldering of a wire to the connector pin. In operation, a wire of a cable is inserted into an interior cavity of the connector pin and resistive heating is applied to the connector pin resulting in the melting of solder contained within the interior cavity. Upon stoppage of the resistive heating by the heat applicator device, the solder within the interior cavity of the connector pin solidifies about the wire to form an electrical connection between the wire and the connector pin. The heat applicator device may then be repositioned to apply resistive heating to each additional connector pin of the electrical connector until all wires of the cable are soldered to their corresponding connector pins on the electrical connector.

Abstract: A method includes transmitting a request for a computer-readable routing diagram, such as a wiring diagram, a pneumatic or hydraulic line diagram, or an optical cable diagram. The method also includes receiving, in response to the request, a routing diagram including a connectable component and at least a portion of a routing set. The connectable component is associated with both a connectable component identifier and the routing set. The routing set contains one or more routable components, such as electrical circuits, pneumatic or hydraulic lines, or optical cables. Further, the method includes displaying, on a display, the routing diagram and at least the portion of the routing set highlighted. Displaying at least the portion of the routing set highlighted occurs in response to an occurrence of the connectable component being selected from the routing diagram displayed on the display or in response to the request including the connectable component identifier.

Abstract: A plunger lift system, as well as a method for monitoring plunger parameters within a wellbore using such a plunger lift system, are provided. The plunger lift system includes a lubricator attached to a wellhead at the surface and a plunger dimensioned to travel through the production tubing upon being released from the lubricator. The plunger lift system also includes magnetic sensor systems installed along the production tubing, where each magnetic sensor system includes a magnetic sensor for detecting the passage of the plunger as it travels through the production tubing, as well a communication device for transmitting communication signals between the magnetic sensor systems and a computing system located at the surface, where the computing system includes a processor and a non-transitory, computer-readable storage medium including computer-executable instructions that direct the processor to dynamically determine the plunger position and/or velocity based on the received communication signals.

Abstract: Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.

Abstract: The present disclosure includes an automotive battery system that uses switching devices to increase operational performance and reliability. The battery system includes a battery cell, a primary switching device electrically coupled to a terminal of the battery cell, and a secondary switching device electrically coupled to the terminal of the battery cell and in parallel with the primary switching device. The primary switching device includes an electromechanical switching device that enables charging or discharging of the battery and generates a boosted voltage. A secondary switching device includes a solid-state switching device and a diode, electrically coupled in series, which detect short circuit conditions in a power-efficient manner and remove the short circuit condition by using the boosted voltage to actuate the armature.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A method of validating a regulated application by generating, on a local data processing system, an automated agent to oversee a validation process of the regulated application on the local data processing system regardless of a local or web-based nature of the regulated application.

Abstract: One aspect of the application can provide a system and method for replacing a failing node with a spare node in a non-uniform memory access (NUMA) system. During operation, in response to determining that a node-migration condition is met, the system can initialize a node controller of the spare node such that accesses to a memory local to the spare node are to be processed by the node controller, quiesce the failing node and the spare node to allow state information of processors on the failing node to be migrated to processors on the spare node, and subsequent to unquiescing the failing node and the spare node, migrate data from the failing node to the spare node while maintaining cache coherence in the NUMA system and while the NUMA system remains in operation, thereby facilitating continuous execution of processes previously executed on the failing node.

Abstract: Provided are processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate, or a salt, solvate, hydrate, enantiomer, mixture of enantiomers, or isotopologue thereof. Also provided are solid forms of various intermediates and products obtained from the processes.

Abstract: The disclosure describes techniques for erecting cases, and particularly example structures and example methods for use in a case erecting system using a robotic arm. A tool for use in robotic case erecting may be used in conjunction with a robotic arm. Use of the tool assists in keeping a case level as the case moves along a conveyor, where a plow closes the major flaps and a tape head tapes edges of the flaps together, thereby sealing the bottom of the case. The tool also assists in regulating the gap between the major flaps, so that the gap and/or any overlap of the flaps is minimized. Accordingly, the tool assists the robotic arm to close the case in a more precise manner.

Abstract: Apparatus and method for decontaminating both contaminated waters and sorbent filter media, either separately or simultaneously, in a single system. Contaminants in a liquid flowing through a reaction chamber are removed by first generating a plasma within the liquid in the chamber, with the contaminants being broken into smaller particles at the interfaces between the generated plasma and the liquid. The combined plasma-liquid solution is then passed through a solid filter, which captures the smaller contaminant particles to decontaminate the liquid. To decontaminate the filter media, plasma flows through the filter material without the presence of liquid, the plasma reacting with the filter material to remove contaminants previously adsorbed by the filter.

Abstract: A tape head assembly—which tapes flaps of boxes on a conveyor—includes power-assist functionality to stretch a first spring used to power a trailing roller to press tape against a trailing case sidewall of a case. A force by the case moving on the conveyor acting upon a leading roller may provide some of the energy to stretch the first spring. However, a roller-assist air cylinder uses compressed air to assist or fully stretch the first spring. A knife assembly may be used to cut the tape applied to a case. A second spring may be stretched by the force of the moving case acting upon a knife arm. The second spring may be used later operate the knife blade. However, a knife-assist air cylinder uses compressed air to assist or fully stretch the second spring. Both assist assemblies may be turned off to operate the tape head in a conventional manner.

Abstract: An exemplary method and system are disclosed to flexibly and adaptably manufacture and assemble a workpiece by using recordings of a user in machine learning/artificial intelligence algorithms to train a robot for subsequent automated manufacture. Machine learning and artificial intelligence learning can generate libraries of generalized dynamic motion primitives that can be subsequently combined for any type of manufacturing or assembling activity. The exemplary method and system can flexibly generate a model of an existing workpiece as a template or primer workpiece that can then be used in conjunction with the DMP operations to fabricate subsequent workpieces.

Abstract: An end-of-arm tool and an associated robotic arm are configured to place items (e.g., soft-sided merchandise) into a case. In an example, an end-of-arm tool is configured to grasp a surface (e.g., the top surface) of an item of merchandise and deposit the item into the case. Accordingly, as an item is deposited, the tool uses contact with that item to move previously placed items back into their preferred locations. After the penultimate item in a row of items is put in place, it may move out of position. As a final item is added to a row, the tool pivots the final item so that a side surface of the final item pushes the penultimate item into its correct position. The tool then pivots the final item to orient the top surface of the item horizontally, and places it in a predetermined position.

Abstract: Techniques for facilitating reservations between a first creative entity and a first venue. Digital audio data for a first creative entity is analyzed to determine acoustic attributes. A plurality of potential venues are determined. A machine learning model is used to calculate an estimated demand metric for the first creative entity for each of the plurality of potential venues, based on a venue profile for the respective venue and acoustic attributes for the first creative entity. Two or more venues are selected and a proposed itinerary is created. A digital order is generated based on the proposed itinerary. User profile data for the first creative entity is updated, upon successful completion of the digital order, and a digital transaction is generated to automatically charge a determined first amount to an account for the first venue and to transfer a determined second amount to an account for the first creative entity.

Abstract: Various apparatus and methods for the atomization of fluid are disclosed herein. In one aspect, an apparatus for atomization of fluid includes a piezoelectric transformer comprising an electrode which is in communication a source of alternating current (AC) voltage at a proximate end of the piezoelectric transformer. A wick which is capable of absorbing a liquid is in contact with the piezoelectric transformer at the distal end, and the piezoelectric transformer is capable of inducing an electrospray of the liquid at the distal end.