Patents by Inventor Michael J. Joyner
Michael J. Joyner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220062637Abstract: This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.Type: ApplicationFiled: November 19, 2021Publication date: March 3, 2022Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Joyner, Bruce D. Johnson, Thomas P. Olson
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Patent number: 11207519Abstract: This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.Type: GrantFiled: May 21, 2019Date of Patent: December 28, 2021Assignee: Mayo Foundation for Medical Education and ResearchInventors: Michael j. Joyner, Bruce D. Johnson, Thomas P. Olson
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Publication number: 20210022620Abstract: In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.Type: ApplicationFiled: July 21, 2020Publication date: January 28, 2021Inventors: Robert W. Techentin, Timothy B. Curry, Michael J. Joyner, David R. Holmes, III, Clifton R. Haider, Christopher L. Felton, Barry K. Gilbert, Charlotte Sue Van Dorn, William A. Carey
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Publication number: 20190269923Abstract: This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.Type: ApplicationFiled: May 21, 2019Publication date: September 5, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael j. Joyner, Bruce D. Johnson, Thomas P. Olson
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Patent number: 10300281Abstract: This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.Type: GrantFiled: March 8, 2013Date of Patent: May 28, 2019Assignee: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Joyner, Bruce D. Johnson, Thomas P. Olson
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Publication number: 20180242655Abstract: Compressive garments described herein include an inner layer, a middle layer coupled to the inner layer, the middle layer comprising a plurality of circuits, each circuit of the plurality of circuits comprising a superelastic cable and a circuit breaker, and a outer layer removably coupled to at least one of the inner layer and the middle layer.Type: ApplicationFiled: February 26, 2018Publication date: August 30, 2018Inventors: Bradley Thomas Holschuh, Lucy Elizabeth Dunne, Robert Michael Theodore Pettys-Baker, Nicholas Edward Schleif, Joonwoo Walter Lee, Mary Ellen Margaret Berglund, Sophia Utset-Ward, Michael J. Joyner, Bruce David Johnson, Kevin Lawrence Kelly, Christopher P. Johnson, Julia Claire Duvall, Rachael Granberry
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Publication number: 20170112564Abstract: This document provides methods and materials involved in treating hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension). For example, methods and materials involved in administering one or more sympatholytic agents to a patient to identify the patient as having an elevated baseline level of sympathetic nerve activity and performing renal denervation on the identified patient to reduce a symptom of hypertension (e.g., resistant hypertension) are provided.Type: ApplicationFiled: April 1, 2015Publication date: April 27, 2017Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Joyner, Timothy B. Curry, Jill N. Barnes
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Publication number: 20170065327Abstract: This document provides methods and materials involved in treating hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), heart failure (e.g., congestive heart failure), or kidney disease (e.g., chronic kidney disease). For example, methods and materials involved in administering one or more sympatholytic agents to a patient to identify the patient as having an elevated baseline level of sympathetic nerve activity and treating the identified patient with a sympatholytic therapy to reduce the symptoms of hypertension (e.g., resistant hypertension), heart failure (e.g., congestive heart failure), or kidney disease (e.g., chronic kidney disease) are provided.Type: ApplicationFiled: April 1, 2015Publication date: March 9, 2017Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael J. Joyner, Timothy B. Curry, Jill N. Barnes
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Patent number: 9315775Abstract: This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided.Type: GrantFiled: June 18, 2014Date of Patent: April 19, 2016Assignees: Mayo Foundation for Medical Education and Research, Dynasil Biomedical CorporationInventors: Michael J. Joyner, Daniel G. Ericson
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Publication number: 20150057313Abstract: This document provides methods and materials for modulating afferent nerve signals to treat medical conditions such as CHF, CHF respiration, dyspnea, peripheral vascular disease (e.g., peripheral arterial disease or venous insufficiency), hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension), COPD, sleep apnea, and chronic forms of lung disease where muscle dysfunction is a part of the disease pathophysiology. For example, methods and materials involved in using electrical and/or chemical techniques to block or reduce afferent nerve signals (e.g., nerve signals of group III and/or IV afferents coming from skeletal muscle and/or the kidneys) are provided.Type: ApplicationFiled: March 8, 2013Publication date: February 26, 2015Inventors: Michael J. Joyner, Bruce D. Johnson, Thomas P. Olson
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Publication number: 20140295402Abstract: This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided.Type: ApplicationFiled: June 18, 2014Publication date: October 2, 2014Inventors: Michael J. Joyner, Daniel G. Ericson
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Publication number: 20130143196Abstract: This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided.Type: ApplicationFiled: March 16, 2012Publication date: June 6, 2013Applicants: Dynasil Biomedical Corporation, Mayo Foundation for Medical Education and ResearchInventors: Michael J. Joyner, Daniel G. Ericson