Abstract: A method of treating increased non-LTR retrotransposition in a cell. The method includes exposing a neural cell to a retrotransposition inhibitor in an amount sufficient to decrease the non-LTR retrotransposition in the neural cell or a progeny of the neural cell. In various embodiments, the non-LTR retrotransposition involves at least one L1 retrotransposon. Also provided is a method of assaying retrotransposition in neural cells. The method includes sorting synchronized neural cells of the same genetic background into single neural cells, and subjecting one or more of the sorted single neural cells to quantitative polymerase chain reaction amplification of at least one retrotransposon. In addition, a method of identifying an inhibitor of retrotransposition and a identifying a neural condition associated with non-LTR retrotransposition are provided.

Abstract: A hand grip device that is easily attached to and removed from the carrying handle of an article such as a plastic merchandise bag, bucket, pail or the like, to provide a relatively wide support surface for improved comfort to the hand of the user, and to prevent separation of the carrying handles of a plastic merchandise bag when the bag is set down. The device comprises a flexible, normally flat body that is easily stored and carried when not in use, and which may be folded about the carrying handle of an article and adjusted along the handle for proper balance. The hand grip device has a longitudinal slit formed in each end, terminating at an enlarged opening for receiving and retaining the carrying handle, and a plurality of flexible fingers or teeth are formed along the slit to facilitate application of the device to a handle, and to securely grip the handle when the device is released, as when the article is set down.