Patents by Inventor Michael J. Oldham

Michael J. Oldham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040171525
    Abstract: Infectious diseases caused by pathogenic microorganisms resident in the alimentary tract of humans and animals can be prevented and treated by administering to the alimentary tract of the human or animal an effective amount of a composition containing at least one lectin capable of binding to an infective microorganism and diminishing its infective capability of the microorganism. The lectin is administered dispensed in a pharmaceutically acceptable non-toxic vehicle. Peptic ulcer disease caused by infection with H. pylori can be treated by oral administration of lectins that bind to the pathogen. A beneficial ecology of H. pylori! can be maintained in infected patients by chronic oral administration of lectins that bind to the pathogen.
    Type: Application
    Filed: September 3, 2003
    Publication date: September 2, 2004
    Applicant: Legere Pharmaceuticals, Ltd.
    Inventors: Howard C. Krivan, Richard C. Potter, Michael J. Oldham
  • Patent number: 6743773
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: June 1, 2004
    Assignee: Legere Pharmaceuticals, Ltd.
    Inventors: Michael J. Oldham, Bruce F. Rose
  • Publication number: 20030158095
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Application
    Filed: November 22, 2002
    Publication date: August 21, 2003
    Inventors: Michael J. Oldham, Bruce F. Rose, Howard C. Krivan
  • Publication number: 20030060516
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Application
    Filed: September 30, 2002
    Publication date: March 27, 2003
    Inventors: Michael J. Oldham, Bruce F. Rose
  • Publication number: 20030045455
    Abstract: Infectious diseases caused by pathogenic microorganisms resident in the alimentary tract of humans and animals can be prevented and treated by administering to the alimentary tract of the human or animal an effective amount of a composition containing at least one lectin capable of binding to an infective microorganism and diminishing its infective capability of the microorganism. The lectin is administered dispersed in a pharmaceutically acceptable non-toxic vehicle. Peptic ulcer disease caused by infection with H. pylori can be treated by oral administration of lectins that bind to the pathogen. A beneficial ecology of H. pylori can be maintained in infected patients by chronic oral administration of lectins that bind to the pathogen.
    Type: Application
    Filed: March 15, 2002
    Publication date: March 6, 2003
    Inventors: Howard C. Krivan, Richard C. Potter, Michael J. Oldham
  • Publication number: 20020183248
    Abstract: Diseases and disorders of dermal tissue such as the skin, hair and nails are treated or prevented by administering one or more lectins, capable of binding to the surface of pathogenic microorganisms inhabiting the hair, skin, and nails, or of binding to the superficial tissues that comprise hair, skin, and nails. The lectins may be administered topically or subcutaneously to a patient infected with pathogenic microorganisms or in danger of being exposed to such pathogens. Lectins that stimulate cell mitosis may also be administered to accelerate wound healing and restore the appearance of age-wrinkled skin. Lectins that coagulate blood can be administered to assist in stopping bleeding from skin lesions. The lectins may be applied to the skin in a pharmceutically acceptable vehicle.
    Type: Application
    Filed: May 24, 2002
    Publication date: December 5, 2002
    Inventors: Michael J. Oldham, Howard C. Krivan, Richard C. Potter
  • Publication number: 20020137674
    Abstract: Infectious diseases caused by pathogenic microorganisms resident in the alimentary tract of humans and animals can be prevented and treated by administering to the alimentary tract of the human or animal an effective amount of a composition containing at least one lectin capable of binding to an infective microorganism and diminishing its infective capability of the microorganism. The lectin is administered dispersed in a pharmaceutically acceptable non-toxic vehicle.
    Type: Application
    Filed: January 8, 2002
    Publication date: September 26, 2002
    Inventors: Michael J. Oldham, Howard C. Krivan
  • Publication number: 20020111297
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Application
    Filed: January 14, 2002
    Publication date: August 15, 2002
    Inventors: Michael J. Oldham, Bruce F. Rose, Howard C. Krivan
  • Publication number: 20020103263
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Application
    Filed: September 18, 1998
    Publication date: August 1, 2002
    Inventors: MICHAEL J. OLDHAM, BRUCE F. ROSE
  • Publication number: 20020082571
    Abstract: Menstrual discharge is coagulated by contacting with one or more lectins capable of agglutinating blood with the menstrual flow to coagulate the blood at least partially, thereby rendering it easier to control and collect. The lectins may be applied either alone, in neat or formulated form, or in conjunction with an intravaginal or extravaginal device. Toxic shock syndrome is prevented by administering one or more lectins capable of diminishing the infective capability of the microorganism causing toxic shock.
    Type: Application
    Filed: December 13, 2001
    Publication date: June 27, 2002
    Inventors: Howard C. Krivan, Michael J. Oldham, Richard C. Potter
  • Publication number: 20020001600
    Abstract: Diseases and disorders of dermal tissue such as the skin, hair and nails are treated or prevented by administering one or more lectins, capable of binding to the surface of pathogenic microorganisms inhabiting the hair, skin, and nails, or of binding to the superficial tissues that comprise hair, skin, and nails. The lectins may be administered topically or subcutaneously to a patient infected with pathogenic microorganisms or in danger of being exposed to such pathogens. Lectins that stimulate cell mitosis may also be administered to accelerate wound healing and restore the appearance of age-wrinkled skin. Lectins that coagulate blood can be administered to assist in stopping bleeding from skin lesions. The lectins may be applied to the skin in a pharmceutically acceptable vehicle.
    Type: Application
    Filed: May 30, 1995
    Publication date: January 3, 2002
    Inventors: MICHAEL J. OLDHAM, HOWARD C. KRIVAN, RICHARD C. POTTER
  • Patent number: 6159174
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: December 12, 2000
    Assignee: Legere Pharmaceuticals, Ltd.
    Inventors: Michael J. Oldham, Bruce F. Rose, Howard C. Krivan
  • Patent number: 6074671
    Abstract: In order to prevent conception and/or infection by sexually transmitted diseases (STDs) one or more lectins capable of binding sperm or agglutinable components of male ejaculate and/or the pathogenic microorganisms responsible for STDs or the carbohydrate moieties expressed on cell surfaces by which the microorganisms bind to the cells, are administered to the vagina prior to sexual intercourse. The lectins prevent conception by binding to the sperm or agglutinable components of male ejaculate to render the sperm incapable of fertilization. They also bind to the pathogenic microorganisms to render them non-pathogenic or to carbohydrates expressed on cell surfaces to prevent infection by the microorganisms or treat such infections. Lectins can also be administered to treat sexually transmitted vaginal infections. The lectins can also be applied to or contained within a condom.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: June 13, 2000
    Assignee: Legere Pharmaceuticals, Ltd.
    Inventors: Michael J. Oldham, Bruce F. Rose, Howard C. Krivan
  • Patent number: 6066338
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections.The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: May 23, 2000
    Assignee: Legere Pharmaceuticals, Ltd.
    Inventors: Michael J. Oldham, Bruce F. Rose, Howard C. Krivan
  • Patent number: 5840771
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: November 24, 1998
    Assignee: Legere Pharmaceuticals, Ltd.
    Inventors: Michael J. Oldham, Bruce F. Rose
  • Patent number: 5766632
    Abstract: In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins immobilize the sperm to render them incapable of fertilization and also bind to the microorganisms to render them non-pathogenic or to the cells to prevent infection by the microorganisms. Lectins can also be administered to treat sexually transmitted vaginal infections. The invention also encompasses a device for to be placed in the vault of the vagina which comprises a ring which surrounds the cervix and a membrane spanning the central aperture of the ring to prevent the direct contact of ejaculate with the cervical tissues. The device is impregnated or coated with lectins and releases them into the vaginal environment over a period of time.
    Type: Grant
    Filed: February 29, 1996
    Date of Patent: June 16, 1998
    Assignee: Legere Pharmaceuticals, Ltd.
    Inventors: Michael J. Oldham, Bruce F. Rose
  • Patent number: 5489066
    Abstract: A system for thoroughly spraying buildings with a pesticide. A truck carries a tank of liquid pesticide, a hose on a reel and a pump for pumping pesticide into the hose. A cart including a tube having a first end for connection to the hose and a second end carrying one or more spray heads is placed at the far end of a building with the hose extending the length of the building and out a door to the truck. The tube is mounted on at least two wheels, with a sled member supporting the end of the tube adjacent to the hose connection. The spray heads produce a pattern in approximately a vertical plane perpendicular to the length of the tube and hose. As the hose is reeled up, the cart is pulled across the floor of the building, with the fan-like spray pattern fully treating the building interior.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: February 6, 1996
    Inventor: Michael J. Oldham