Patents by Inventor Michael John Bennett
Michael John Bennett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220404062Abstract: The present disclosure relates to an air-diffusion system, a computer-implemented method of designing an air-diffusion system, an apparatus for additive manufacturing an air-diffusion system, and a method of additive manufacturing an air-diffusion system.Type: ApplicationFiled: May 10, 2022Publication date: December 22, 2022Inventors: Ninotschka Anna Titchkosky, Tim Schork, Christopher James Bickerton, Michael John Bennett, Mitchell Robert Page, David Anthony Pigram, Tran Tuan Anh Dang
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Patent number: 10807982Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: GrantFiled: November 4, 2019Date of Patent: October 20, 2020Assignee: Celgene Quanticel Research, Inc.Inventors: Michael John Bennett, Juan Manual Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James M. Veal
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Publication number: 20200071332Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: ApplicationFiled: November 4, 2019Publication date: March 5, 2020Applicant: CELGENE QUANTICEL RESEARCH, INC.Inventors: Michael John Bennett, Juan Manual Betancort, Amogh Boioor, Stephen W. Kaidor, Jeffrey Alan Stafford, James M. Veal
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Patent number: 10494371Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: GrantFiled: January 12, 2018Date of Patent: December 3, 2019Assignee: CELGENE QUANTICEL RESEARCH, INC.Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James Marvin Veal
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Patent number: 10202360Abstract: The present disclosure relates to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease.Type: GrantFiled: April 17, 2017Date of Patent: February 12, 2019Assignee: CELGENE QUANTICEL RESEARCH, INC.Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Toufike Kanouni, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
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Publication number: 20180134710Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: ApplicationFiled: January 12, 2018Publication date: May 17, 2018Applicant: CELGENE QUANTICEL RESEARCH, INC.Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James Marvin Veal
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Patent number: 9908885Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: GrantFiled: April 15, 2016Date of Patent: March 6, 2018Assignee: CELGENE QUANTICEL RESEARCH, INC.Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James Marvin Veal
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Publication number: 20170298040Abstract: The present disclosure relates to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease.Type: ApplicationFiled: April 17, 2017Publication date: October 19, 2017Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Toufike Kanouni, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
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Publication number: 20170050968Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: ApplicationFiled: April 15, 2016Publication date: February 23, 2017Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James Marvin Veal
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Publication number: 20160115134Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: ApplicationFiled: July 1, 2015Publication date: April 28, 2016Inventors: Michael John Bennett, Jeffrey Alan Stafford
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Patent number: 9115114Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: GrantFiled: March 13, 2015Date of Patent: August 25, 2015Assignee: QUANTICEL PHARMACEUTICALS, INC.Inventors: Michael John Bennett, Jeffrey Alan Stafford
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Publication number: 20150183784Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: ApplicationFiled: March 13, 2015Publication date: July 2, 2015Inventors: Michael John Bennett, Jeffrey Alan Stafford
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Patent number: 9034900Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: GrantFiled: October 17, 2014Date of Patent: May 19, 2015Assignee: Quanticel Pharmaceuticals, Inc.Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James Marvin Veal
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Publication number: 20150111885Abstract: The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.Type: ApplicationFiled: October 17, 2014Publication date: April 23, 2015Inventors: Michael John Bennett, Juan Manuel Betancort, Amogh Boloor, Stephen W. Kaldor, Jeffrey Alan Stafford, James Marvin Veal
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Patent number: 8956484Abstract: Disclosed herein are methods for bonding refractory substrates, such as zircon substrates, without the use of a bonding agent. Exemplary methods include (a) providing a plurality of refractory components, each component having at least one surface to be bonded, (b) polishing each surface to be bonded to a surface roughness (Ra) of 200 nm or finer, (c) contacting the surfaces to be bonded to form an unbonded refractory substrate, (d) firing the unbonded refractory substrate, and (e) subjecting the surfaces to be bonded to a compressive force during firing. Methods for making refractory forming bodies are also disclosed herein.Type: GrantFiled: November 26, 2012Date of Patent: February 17, 2015Assignee: Corning IncorporatedInventors: William Peter Addiego, Michael John Bennett, Michael Patrick Carson, Jeffrey Scott Davis, Martin Herbert Goller, Benjamin Zain Hanson, Tracey Lynn Timmons
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Patent number: 8801834Abstract: An article having a flow-through substrate having open channels defined by porous walls, wherein the flow-through substrate includes alumina; and a CO2 sorbent disposed on the flow-through substrate, wherein the CO2 sorbent impregnates the porous walls of the flow-through substrate. Methods of making the article, its use for CO2 capture, and methods for regenerating the article for further use are also disclosed.Type: GrantFiled: February 15, 2012Date of Patent: August 12, 2014Assignee: Corning IncorporatedInventors: William Peter Addiego, Michael John Bennett
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Publication number: 20140144571Abstract: Disclosed herein are methods for bonding refractory substrates, such as zircon substrates, without the use of a bonding agent. Exemplary methods include (a) providing a plurality of refractory components, each component having at least one surface to be bonded, (b) polishing each surface to be bonded to a surface roughness (Ra) of 200 nm or finer, (c) contacting the surfaces to be bonded to form an unbonded refractory substrate, (d) firing the unbonded refractory substrate, and (e) subjecting the surfaces to be bonded to a compressive force during firing.Type: ApplicationFiled: November 26, 2012Publication date: May 29, 2014Inventors: William Peter Addiego, Michael John Bennett, Michael Patrick Carson, Jeffrey Scott Davis, Martin Herbert Goller, Benjamin Zain Hanson, Tracey Lynn Timmons
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Publication number: 20120216676Abstract: An article having a flow-through substrate having open channels defined by porous walls, wherein the flow-through substrate includes alumina; and a CO2 sorbent disposed on the flow-through substrate, wherein the CO2 sorbent impregnates the porous walls of the flow-through substrate. Methods of making the article, its use for CO2 capture, and methods for regenerating the article for further use are also disclosed.Type: ApplicationFiled: February 15, 2012Publication date: August 30, 2012Inventors: William Peter Addiego, Michael John Bennett
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Publication number: 20120220450Abstract: A method of coating a substrate with a catalytically active material using a polymer latex is disclosed. A slurry of catalytically active material and water is prepared, the catalytically active material containing activated carbon, and a binder is prepared that contains a polymer latex having a glass transition temperature of 10 C to 30 C. The slurry is combined with the binder to form a mixture, which can then be applied to the substrate to achieve a mixture loading of 20 to 30 weight percent on the substrate. The latex polymer binders can bind a catalytically active platinum on activated carbon powder to a cordierite honeycomb while not interfering with its catalytic activity, such as for hydrogenation.Type: ApplicationFiled: February 17, 2012Publication date: August 30, 2012Inventors: William Peter Addiego, Michael John Bennett
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Patent number: 4079198Abstract: An electro-acoustic impedance bridge for measuring the acoustic impedance of the human ear over a predetermined frequency range compares the magnitude and phase of the variable-frequency sound driving both the human ear and the artificial ear (acoustic coupler).Type: GrantFiled: July 21, 1976Date of Patent: March 14, 1978Inventor: Michael John Bennett