Patents by Inventor Michael John Tisdale

Michael John Tisdale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment of muscle loss
    Patent number: 8329646
    Abstract: The invention provides methods for treating muscle loss in an individual. In one embodiment, the invention includes administering to an individual an effective amount of a branched chain amino acid (BCAA), a BCAA precursor, a BCAA metabolite, a BCAA-rich protein, a protein manipulated to enrich the BCAA content or any combination thereof. The invention further provides nutritional products for such administration, including orally-administrable nutritional products.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: December 11, 2012
    Assignee: Nestec S.A.
    Inventors: Michael John Tisdale, Norman Alan Greenberg, Helen Laura Eley, Kevin Burke Miller
  • TREATMENT OF CACHEXIA
    Publication number: 20120301404
    Abstract: The invention characterizes and provides a receptor for Proteolysis Inducing Factor (PIF) and associated methods and materials employing the same. These have utility, for example, in the provision of treatments for cachexia.
    Type: Application
    Filed: June 25, 2012
    Publication date: November 29, 2012
    Inventors: Michael John Tisdale, Penio Todorov, Stacey Marie Wyke
  • Antibodies to proteolysis inducing factor (PIF) receptor and methods of use thereof
    Patent number: 8207310
    Abstract: The invention characterises and provides a receptor for Proteolysis Inducing Factor (PIF) and associated methods and materials employing the same. These have utility, for example, in the provision of treatments for cachexia.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: June 26, 2012
    Assignee: Ashton University
    Inventors: Michael John Tisdale, Penio Todorov, Stacey Marie Wyke
  • COMPOSITIONS AND METHODS FOR INHIBITING THE ACTIVATION OF DSRNA-DEPENDENT PROTEIN KINASE AND TUMOR GROWTH INHIBITION
    Publication number: 20110077198
    Abstract: The present invention relates to compositions and methods for preventing and treating a condition in a mammalian subject that include at least one inhibitor of double stranded RNA dependent protein kinase (PKR-I) prior to or concurrently with the treatment, wherein the treatment results to an inhibition of activation of dsRNA-dependent protein kinase. The compositions and methods of the present invention further include at least one potentiator that further enhances the inhibition of phosphorylation by PKR-I.
    Type: Application
    Filed: October 3, 2008
    Publication date: March 31, 2011
    Inventors: Michael John Tisdale, Helen Laura Eley, Steve Thomas Russell, Kevin Burke Miller
  • Antiproliferative agents
    Patent number: 7750181
    Abstract: This invention relates to certain dioxodihydropyridine derivatives and certain methacrylic acid and furan derivative precursors thereof, processes for their preparation, pharmaceutical compositions containing such compounds and their use as anti-proliferative agents, especially tumour growth inhibitors and anti-cancer agents, antibiotics and/or antiviral agents.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: July 6, 2010
    Assignee: EPX Research Limited
    Inventors: Washington Odur Ayuko, Michael John Tisdale, Eric Lattmann
  • Treatment of Cachexia
    Publication number: 20100111974
    Abstract: The invention characterises and provides a receptor for Proteolysis Inducing Factor (PIF) and associated methods and materials employing the same. These have utility, for example, in the provision of treatments for cachexia.
    Type: Application
    Filed: December 11, 2007
    Publication date: May 6, 2010
    Inventors: Michael John Tisdale, Penio Todorov, Stacey Marie Wyke
  • METHODS FOR THE TREATMENT OF MUSCLE LOSS
    Publication number: 20090105123
    Abstract: The invention provides methods for treating muscle loss in an individual. In one embodiment, the invention includes administering to an individual an effective amount of a branched chain amino acid (BCAA), a BCAA precursor, a BCAA metabolite, a BCAA-rich protein, a protein manipulated to enrich the BCAA content or any combination thereof.
    Type: Application
    Filed: November 28, 2006
    Publication date: April 23, 2009
    Inventors: Michael John Tisdale, Norman Alan Greenberg, Helen Laura Eley, Kevin Burke Miller
  • Antiproliferative agents
    Patent number: 7049338
    Abstract: This invention relates to certain dioxodihydropyridine derivatives and certain methacrylic acid and furan derivative precursors thereof, processes for their preparation, pharmaceutical compositions containing such compounds and their use as anti-proliferative agents, especially tumor growth inhibitors and anti-cancer agents, antibiotics and/or antiviral agents.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: May 23, 2006
    Inventors: Washington Odur Ayuko, Michael John Tisdale, Eric Lattmann
  • Antiproliferative agents
    Patent number: 6881846
    Abstract: This invention relates to certain dioxodihydropyridine derivatives and certain methacrylic acid and furan derivative precursors thereof, processes for their preparation, pharmaceutical compositions containing such compounds and their use as anti-proliferative agents, especially tumour growth inhibitors and anti-cancer agents, antibiotics and/or antiviral agents.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: April 19, 2005
    Assignee: EPX Research Limited
    Inventors: Washington Odur Ayuko, Michael John Tisdale, Eric Lattmann
  • Antiproliferative agents
    Publication number: 20040106648
    Abstract: This invention relates to certain dioxodihydropyridine derivatives and certain methacrylic acid and furan derivative precursors thereof, processes for their preparation, pharmaceutical compositions containing such compounds and their use as anti-proliferative agents, especially tumour growth inhibitors and anti-cancer agents, antibiotics and/or antiviral agents.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 3, 2004
    Applicant: EPX Research Limited
    Inventors: Washington Odur Ayuko, Michael John Tisdale, Eric Lattmann
  • Use of quinone and hydroquinone derivatives for the treatment of cachexia
    Patent number: 6133278
    Abstract: A pharmaceutical composition for treating cachexia which containing a compound (I) ##STR1## wherein R.sup.1, R.sup.2 is H, alkyl, alkoxy, may form --CH.dbd.CH--CH.dbd.CH--; R.sup.3 is H, alkyl; R.sup.4 is N-containing heterocyclic; R.sup.5 is H, alkyl, hydroxyalkyl, carboxyl; Z is ##STR2## (R.sup.0 is H, alkyl); n is 0-12; m is 0-3; k is 0-7, or a salt thereof.
    Type: Grant
    Filed: September 14, 1995
    Date of Patent: October 17, 2000
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Shinji Terao, Michael John Tisdale