Abstract: The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

Abstract: Systems and methods for activating a remote device may include receiving, at a computing device, an authorization request regarding the transaction. The authorization request may be received from a user mobile device. Once the authorization request is received, the translation information may be translated into a data structure that corresponds to a payment processor. The data structure may be transmitted to the payment processor. An authorization message may be transmitted to a point-of sale device.

Abstract: At least one of a measure of trust or a measure of spoofing risk associated with a sender of a message is determined. A measure of similarity between an identifier of the sender of the message and an identifier of at least one trusted contact of a recipient of the message is determined. The measure of similarity is combined with at least one of the measure of trust or the measure of spoofing risk to at least in part determine a combined measure of risk associated with the message. The sender of the message is not included in the at least one trusted contact of the recipient of the message. Based at least in part on the combined measure of risk associated with the message, the message is modified to alter content of a data field that includes an identification of the sender of the message.

Abstract: A measure of similarity between an identifier of a sender of the message and each identifier of one or more identifiers of each trusted contact of a plurality of trusted contacts of a recipient of the message is determined. In the event the sender of the message is not any of the trusted contacts but at least one of the measure of similarity between the identifier of the sender of the message and a selected identifier of a selected trusted contact of the plurality of trusted contacts meets a threshold, the message is modified, if applicable, to alter content of a data field that includes an identification of the sender of the message. The data field is one of a plurality of data fields included in a header of the message.

Abstract: An immunoassay-multiplexing apparatus includes a microplate having an array of cells. Each cell may have the same configuration, or different configurations. In at least one cell, there is a container within the cell. Within the container is a loading well and at least one satellite well. Each satellite well is connected to the loading well by a unique and independent interconnect channel. Each interconnect channel can taper inwardly transitioning from the associated satellite well to the loading well. Further, a sealing member is used to seal the cell.

Abstract: A solution for forming a marker or filler mass for an intracorporeal site. The solution contains a polar, water soluble non-aqueous solvent such as dimethyl sulfoxide and a bioabsorbable, essentially water insoluble polymer such as polylactic acid, or copolymers of lactic acid and glycolic acid. The solution may be delivered to the biopsy site by a suitable syringe and delivery tube. The delivery tube is preferably provided with a releasable radiopaque element on the distal tip which can be released within the polymeric marker mass formed in the biopsy cavity.

Abstract: A method and system for treating restless leg syndrome. The system includes a vibration generator and a controller operable to provide counter-stimulation vibration to a patient suffering from restless leg syndrome. The counter-stimulation may be provided at a frequency of between 1 cycle/minute to 1000 cycles per second and at an amplitude and duration sufficient to act as a counter-stimulation vibration to restless leg syndrome but low enough to allow the patient to sleep.

Abstract: Systems and methods for providing a payment messaging interface may include receiving, at a computing device comprising a processor, transaction information regarding the transaction. Once the transaction information is received, the transaction information may be translated into a data structure that corresponds to a payment processor. Once the transaction information has been translated, the data structure may be transmitted to the payment processor.

Abstract: An endoluminal needle or punch is describes wherein the distal end of the endoluminal needle is able to articulate laterally out of the longitudinal axis of the steerable endoluminal needle. The endoluminal needle further comprise a blunted distal end configuration that is minimally traumatic. Under control by the user, at the proximal end of the endoluminal needle, a sharp stylet can be advanced to punch tissue and then be retracted to maximize safety. The endoluminal needle is configured for use within an introducer.

Abstract: An intracorporeal marker system includes a tissue marker pellet comprised of a polysaccharide material. The intracorporeal marker system may also include a fibrous marker of bioabsorbable fibers. In one embodiment, for example, an outer layer of bioabsorbable fibers is disposed around at least part of an inner core of bioabsorbable fibers.

Abstract: A tissue marker delivery device includes an elongated marker insertion tube having a closed distal end. The closed distal end has a plurality of connected slits that form a plurality of openable petals. A piston is slidably disposed within the elongated marker insertion tube. At least one tissue marker is slidably disposed within the elongated marker insertion tube at a location distal to the piston and proximal to the closed distal end of the elongated marker insertion tube.

Abstract: A system for at least partially filling and marking a cavity within a patient includes a delivery device. A quantity of marker forming fluid is located within the delivery device. The quantity of marker forming fluid is configured to at least partially fill the cavity and form therein a bioabsorbable body after delivery into the cavity from the delivery device. A radiopaque marker, separate from the quantity of marker forming fluid and releasably attached to a portion of the delivery device, is configured to be delivered into the quantity of marker forming fluid in the cavity from the delivery device and configured to remain in the bioabsorbable body upon the formation of the bioabsorbable body in the cavity.

Abstract: An endoluminal needle or punch is describes wherein the distal end of the endoluminal needle is able to articulate laterally out of the longitudinal axis of the steerable endoluminal needle. The endoluminal needle further comprise a blunted distal end configuration that is minimally traumatic. Under control by the user, at the proximal end of the endoluminal needle, a sharp stylet can be advanced to punch tissue and then be retracted to maximize safety. The endoluminal needle is configured for use within an introducer.

Abstract: A tissue marker delivery device includes a hollow cannula and a fibrous marker. The hollow cannula has a distal region. The fibrous marker is disposed within the distal region. The fibrous marker includes a plurality of bioabsorbable strands, and a binding agent. Optionally, the tissue marker delivery device may include a short-term marker that includes an imagable agent that does not interfere with imaging adjacent tissue.

Abstract: A first risk analysis of a message is performed. In the event the first risk analysis results in a determination that the message meets a first criteria, at least a portion of the message is modified prior to sending a modified version of the message to a specified recipient of the message, and a second risk analysis of the message is performed. The first risk analysis is performed before sending the modified version of the message and the modified version of the message is sent to the specified recipient of the message prior to a conclusion of the second risk analysis. In the event the second risk analysis results in a determination that the message meets a second criteria, content of the message that was previously prevented from being accessed by the specified recipient is provided to the specified recipient of the message.

Abstract: A measure of similarity between an identifier of a sender of the message and each identifier of one or more identifiers of each trusted contact of a plurality of trusted contacts of a recipient of the message is determined. In the event the sender of the message is not any of the trusted contacts but at least one of the measure of similarity between the identifier of the sender of the message and a selected identifier of a selected trusted contact of the plurality of trusted contacts meets a threshold, the message is modified, if applicable, to alter content of a data field that includes an identification of the sender of the message. The data field is one of a plurality of data fields included in a header of the message.

Abstract: A tissue marker and tissue marking system is provided for treating and/or marking a site within a patient from which tissue has been removed. The tissue marker includes a press-formed marker body of 65% (by wt.) powder of corn starch or potato starch and 35% (by wt.) methylcellulose binder.

Abstract: A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. A plunger is slidably disposed within the inner lumen of the elongated delivery cannula. The plunger has a distal end. At least one elongated fibrous marker body is pre-formed prior to being inserted into the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula at a location distal to the distal end of the plunger. The pre-formed at least one elongated fibrous marker body includes a fibrous material compressed and impregnated with a binding agent and freeze dried in the compressed condition. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body.

Abstract: A measure of similarity between an identifier of a sender of the message and each identifier of one or more identifiers of each trusted contact of a plurality of trusted contacts of a recipient of the message is determined. In the event the sender of the message is not any of the trusted contacts but at least one of the measure of similarity between the identifier of the sender of the message and a selected identifier of a selected trusted contact of the plurality of trusted contacts meets a threshold, the message is modified, if applicable, to alter content of a data field that includes an identification of the sender of the message. The data field is one of a plurality of data fields included in a header of the message.

Abstract: A method for treating a site within a patient from which tissue has been removed includes providing at least one press-formed marker body formed of polysaccharide and a suitable binder; and placing the at least one of the press-formed marker body within the site where tissue has been removed so as to provide hemostasis therein.